Gene Page: MAP1A

Summary
GeneID  4130
Symbol  MAP1A
Synonyms  FLJ77111|MAP1L|MTAP1A
Description  microtubule-associated protein 1A
See related  HGNC:6835|MIM:600178|Ensembl:ENSG00000166963|HPRD:02549|
Locus tag  -
Gene type  protein-coding
Map location  15q13-qter
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.7246 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
BCAS10.960.97
MOBP0.930.94
KIF1C0.910.89
PAQR60.900.93
SEPT40.890.90
TP53INP20.870.86
FOXO40.860.81
PLEKHB10.850.93
ZFP570.850.87
DAAM20.820.87
Top 10 negatively co-expressed genes
PARP6-0.67-0.78
GSTA4-0.67-0.81
PPP3CC-0.66-0.79
SUPV3L1-0.66-0.78
DUSP12-0.66-0.79
UBE2E3-0.66-0.77
MED19-0.66-0.78
STMN1-0.65-0.80
MLLT11-0.65-0.78
CDC42-0.65-0.78
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI12812986 
GO:0005198structural molecule activityNAS8812494 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005874microtubuleIEA-
GO:0005875microtubule associated complexTAS8812494 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP1G1ADTG | CLAPG1 | MGC18255adaptor-related protein complex 1, gamma 1 subunit-HPRD10747088 |11418592 
DISC1C1orf136 | FLJ13381 | FLJ21640 | FLJ25311 | FLJ41105 | KIAA0457 | SCZD9disrupted in schizophrenia 1-HPRD,BioGRID12812986 
DISC-1 interacts with MAP1A.BIND12812986 
DLG1DKFZp761P0818 | DKFZp781B0426 | DLGH1 | SAP97 | dJ1061C18.1.1 | hdlgdiscs, large homolog 1 (Drosophila)-HPRD9786987 
DLG2DKFZp781D1854 | DKFZp781E0954 | FLJ37266 | MGC131811 | PSD-93discs, large homolog 2, chapsyn-110 (Drosophila)-HPRD9786987 
DLG4FLJ97752 | FLJ98574 | PSD95 | SAP90discs, large homolog 4 (Drosophila)-HPRD,BioGRID9786987 |11925566 
MAP1BDKFZp686E1099 | DKFZp686F1345 | FLJ38954 | FUTSCH | MAP5microtubule-associated protein 1B-HPRD,BioGRID2470876 |11002287 
MAP1LC3ALC3 | LC3A | MAP1ALC3 | MAP1BLC3microtubule-associated protein 1 light chain 3 alpha-HPRD2470876 |7908909 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2A-HPRD11278895 
UPF2DKFZp434D222 | HUPF2 | KIAA1408 | MGC138834 | MGC138835 | RENT2 | smg-3UPF2 regulator of nonsense transcripts homolog (yeast)-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_UP 4429All SZGR genes in this pathway
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN 3520All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B 392251All SZGR genes in this pathway
PETRETTO_BLOOD_PRESSURE_UP 128All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
ROSS_AML_WITH_PML_RARA_FUSION 7762All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR 532309All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C2 5439All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_DN 178121All SZGR genes in this pathway
LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES 3726All SZGR genes in this pathway
VALK_AML_WITH_FLT3_ITD 4022All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_30MIN_DN 15099All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_UP 217131All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_GROUP1 13676All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_EARLY_LATE 317190All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/2069279341A,m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-181582588m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-199962968m8hsa-miR-199aCCCAGUGUUCAGACUACCUGUUC
hsa-miR-199bCCCAGUGUUUAGACUAUCUGUUC
miR-2186997051Ahsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-266006061Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-34/449876882m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-34b877883m8hsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
miR-377912918m8hsa-miR-377AUCACACAAAGGCAACUUUUGU
miR-409-3p926932m8hsa-miR-409-3pCGAAUGUUGCUCGGUGAACCCCU
miR-49113081314m8hsa-miR-491brainAGUGGGGAACCCUUCCAUGAGGA
miR-9193199m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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