Gene Page: MAP2

Summary
GeneID  4133
Symbol  MAP2
Synonyms  DKFZp686I2148|MAP2A|MAP2B|MAP2C
Description  microtubule-associated protein 2
See related  HGNC:6839|MIM:157130|Ensembl:ENSG00000078018|HPRD:01140|
Locus tag  -
Gene type  protein-coding
Map location  2q34-q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 1.2138 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND-
GO:0005516calmodulin bindingIEA-
GO:0005198structural molecule activityNAS9588626 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007026negative regulation of microtubule depolymerizationIEA-
GO:0008150biological_processND-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIEA-
GO:0005874microtubuleIEA-
GO:0005875microtubule associated complexNAS7854050 
GO:0005875microtubule associated complexTAS9588626 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APOEAD2 | LPG | MGC1571 | apoproteinapolipoprotein E-HPRD8624078 
CPEB1CEBP | CPE-BP1 | CPEB | FLJ13203 | MGC34136 | MGC60106cytoplasmic polyadenylation element binding protein 1-HPRD12629046 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YESAffinity Capture-WesternBioGRID11546790 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2-HPRD,BioGRID10781592 |11546790|11546790 
GRIN1NMDA1 | NMDAR1 | NR1glutamate receptor, ionotropic, N-methyl D-aspartate 1-HPRD10862698 
GRIN2DEB11 | NMDAR2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2D-HPRD10862698 
MAP2DKFZp686I2148 | MAP2A | MAP2B | MAP2Cmicrotubule-associated protein 2-HPRD,BioGRID10527895 
MARK4FLJ90097 | KIAA1860 | MARKL1 | Nbla00650MAP/microtubule affinity-regulating kinase 4-HPRD,BioGRID14594945 
MYO7ADFNA11 | DFNB2 | MYOVIIA | MYU7A | NSRD2 | USH1Bmyosin VIIA-HPRD,BioGRID11171103 
NEFLCMT1F | CMT2E | FLJ53642 | NF-L | NF68 | NFLneurofilament, light polypeptideReconstituted ComplexBioGRID1902666 
PLEC1EBS1 | EBSO | HD1 | PCN | PLEC1b | PLTNplectin 1, intermediate filament binding protein 500kDa-HPRD,BioGRID3027087 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)Reconstituted ComplexBioGRID10781592 
TTBK1BDTK | KIAA1855 | RP3-330M21.4tau tubulin kinase 1-HPRD7556643 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_AKAPCENTROSOME_PATHWAY 1514All SZGR genes in this pathway
PID_LKB1_PATHWAY 4737All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN 198110All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_DN 7752All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_UP 2115All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_10HR_UP 10169All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_UP 8152All SZGR genes in this pathway
LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES 3726All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
MASSARWEH_RESPONSE_TO_ESTRADIOL 6147All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN 353226All SZGR genes in this pathway
HUANG_FOXA2_TARGETS_UP 4528All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP 11170All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN 6845All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_PR_DN 4434All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_EARLY_LATE 317190All SZGR genes in this pathway
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN 229135All SZGR genes in this pathway
TERAO_AOX4_TARGETS_SKIN_UP 3827All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP 279155All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_UP 266142All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p34773483m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-139121127m8hsa-miR-139brainUCUACAGUGCACGUGUCU
miR-141/200a4814871Ahsa-miR-141UAACACUGUCUGGUAAAGAUGG
hsa-miR-200aUAACACUGUCUGGUAACGAUGU
miR-17-5p/20/93.mr/106/519.d658664m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-18682891A,m8hsa-miR-186CAAAGAAUUCUCCUUUUGGGCUU
miR-19435893595m8hsa-miR-194UGUAACAGCAACUCCAUGUGGA
hsa-miR-194UGUAACAGCAACUCCAUGUGGA
miR-200bc/4292642701Ahsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-214292229291A,m8hsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-238938991Ahsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-268228291A,m8hsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-30-5p111511211Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-3354349m8hsa-miR-335brainUCAAGAGCAAUAACGAAAAAUGU
miR-33835153521m8hsa-miR-338brainUCCAGCAUCAGUGAUUUUGUUGA
miR-361357235791A,m8hsa-miR-361brainUUAUCAGAAUCUCCAGGGGUAC
miR-369-3p265271m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374764770m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-3814904961Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-450347734831Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
miR-496457463m8hsa-miR-496AUUACAUGGCCAAUCUC
miR-539788794m8hsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
miR-5441671741A,m8hsa-miR-544AUUCUGCAUUUUUAGCAAGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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