Gene Page: MDM2

Summary
GeneID  4193
Symbol  MDM2
Synonyms  HDMX|MGC71221|hdm2
Description  Mdm2 p53 binding protein homolog (mouse)
See related  HGNC:6973|MIM:164785|Ensembl:ENSG00000135679|HPRD:01272|
Locus tag  -
Gene type  protein-coding
Map location  12q14.3-q15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0316 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRA2B0.940.93
DKC10.930.92
TSR10.930.92
TARDBP0.930.92
UBE2I0.930.90
SSRP10.920.93
DHX90.920.92
NUP2050.920.94
HNRNPK0.920.92
DDX230.920.93
Top 10 negatively co-expressed genes
MT-CO2-0.75-0.85
AF347015.31-0.75-0.85
FXYD1-0.74-0.85
C5orf53-0.74-0.77
IFI27-0.74-0.85
AF347015.33-0.72-0.83
AF347015.27-0.71-0.83
HIGD1B-0.71-0.84
MT-CYB-0.70-0.81
HLA-F-0.70-0.75
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0002039p53 bindingIEA-
GO:0005515protein bindingIEA-
GO:0004842ubiquitin-protein ligase activityIDA9450543 
GO:0004842ubiquitin-protein ligase activityIEA-
GO:0016874ligase activityIEA-
GO:0008270zinc ion bindingIDA10722742 
GO:0008270zinc ion bindingIEA-
GO:0042802identical protein bindingIPI17936559 
GO:0019899enzyme bindingIPI15577914 
GO:0017163negative regulator of basal transcription activityIDA9271120 
GO:0017163negative regulator of basal transcription activityISS-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000122negative regulation of transcription from RNA polymerase II promoterIDA9271120 
GO:0000122negative regulation of transcription from RNA polymerase II promoterISS-
GO:0006461protein complex assemblyIDA10608892 |12915590 
GO:0006511ubiquitin-dependent protein catabolic processIEA-
GO:0007089traversing start control point of mitotic cell cycleIEA-
GO:0008285negative regulation of cell proliferationTAS7791904 
GO:0016567protein ubiquitinationIDA9450543 
GO:0016567protein ubiquitinationIEA-
GO:0042176regulation of protein catabolic processIDA9153395 
GO:0030163protein catabolic processIEA-
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP11715018 
GO:0005622intracellularIEA-
GO:0005626insoluble fractionIDA12915590 
GO:0005634nucleusIEA-
GO:0005654nucleoplasmEXP11331603 
GO:0005654nucleoplasmIDA10707090 |12915590 
GO:0005730nucleolusIDA10707090 
GO:0005730nucleolusIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ABL1ABL | JTK7 | bcr/abl | c-ABL | p150 | v-ablc-abl oncogene 1, receptor tyrosine kinase-HPRD,BioGRID12110584 
AKT1AKT | MGC99656 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHAv-akt murine thymoma viral oncogene homolog 1HDM2 interacts with and is phosphorylated by Akt.BIND11960368 
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptor-HPRD12145204 
ARRB1ARB1 | ARR1arrestin, beta 1Affinity Capture-WesternBioGRID12538596 
ARRB2ARB2 | ARR2 | BARR2 | DKFZp686L0365arrestin, beta 2-HPRD,BioGRID12488444 |12538596 
-HPRD11588219 |12488444 
|12538596|12488444 |12538596 
CCNG1CCNGcyclin G1-HPRD,BioGRID12556559 
CDKN1ACAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1cyclin-dependent kinase inhibitor 1A (p21, Cip1)Mdm2 interacts with the p21 promoter.BIND15546622 
CDKN2AARF | CDK4I | CDKN2 | CMM2 | INK4 | INK4a | MLM | MTS1 | TP16 | p14 | p14ARF | p16 | p16INK4 | p16INK4a | p19cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)-HPRD9529248 |12085228|9529249 
p14ARF interacts with an unspecified isoform of Mdm2.BIND12582152 
Affinity Capture-MS
Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID9529248 |9529249 
|12085228 |14612427 
Mdm2 interacts with p14ARF.BIND10822382 
p14 interacts with MDM2.BIND15355988 
MDM2 interacts with p14ARFBIND9653180 
CTBP1BARS | MGC104684C-terminal binding protein 1Affinity Capture-Western
Far Western		BioGRID12867035 
CTBP2-C-terminal binding protein 2Affinity Capture-Western
Reconstituted Complex		BioGRID12867035 
DHCR24KIAA0018 | Nbla03646 | SELADIN1 | seladin-124-dehydrocholesterol reductaseSeladin-1 interacts with an unspecified isoform of Mdm2.BIND15577914 
EID1C15orf3 | CRI1 | EID-1 | IRO45620 | MGC138883 | MGC138884 | PNAS-22 | PTD014 | RBP21EP300 interacting inhibitor of differentiation 1-HPRD,BioGRID11073989 
EP300KAT3B | p300E1A binding protein p300-HPRD,BioGRID9809062 
ESR1DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1estrogen receptor 1Reconstituted ComplexBioGRID10766163 
GTF2E1FE | TF2E1 | TFIIE-Ageneral transcription factor IIE, polypeptide 1, alpha 56kDaReconstituted ComplexBioGRID9271120 
GTF2E2FE | TF2E2 | TFIIE-Bgeneral transcription factor IIE, polypeptide 2, beta 34kDa-HPRD9271120 
HDAC1DKFZp686H12203 | GON-10 | HD1 | RPD3 | RPD3L1histone deacetylase 1-HPRD,BioGRID12426395 
HIF1AHIF-1alpha | HIF1 | HIF1-ALPHA | MOP1 | PASD8hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Affinity Capture-Western
Biochemical Activity
Reconstituted Complex		BioGRID10640274 |12606552 
-HPRD10640274|12606552 
HIST3H3H3.4 | H3/g | H3FT | H3t | MGC126886 | MGC126888histone cluster 3, H3Mdm2 interacts with H3.BIND15546622 
HIST4H4H4/p | MGC24116histone cluster 4, H4Mdm2 interacts with H4.BIND15546622 
KAT2BCAF | P | P/CAF | PCAFK(lysine) acetyltransferase 2B-HPRD,BioGRID12068014 
KAT5ESA1 | HTATIP | HTATIP1 | PLIP | TIP | TIP60 | cPLA2K(lysine) acetyltransferase 5-HPRD,BioGRID11927554 
MAPKAPK2MK2mitogen-activated protein kinase-activated protein kinase 2MDM2 (HDM2) interacts with MAPKAPK2 isoform 1 (MK2). This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human MAPKAPK2.BIND15688025 
MDM2 (HDM2) interacts with MAPKAPK2 (MK2) isoform 2. This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human MAPKAPK2.BIND15688025 
MDC1DKFZp781A0122 | KIAA0170 | MGC166888 | NFBD1mediator of DNA damage checkpoint 1Protein-peptideBioGRID14578343 
MDM2HDMX | MGC71221 | hdm2Mdm2 p53 binding protein homolog (mouse)Mdm2 auto-ubiquitinates. This interaction was modeled on a demonstrated interaction between Mdm2 from an unspecified species.BIND16023600 
Biochemical ActivityBioGRID10722742 
Mdm2 ubiquitinates itself.BIND10822382 
An unspecified isoform of MDM2 interacts and ubiquitinates itself intermolecularly. This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species.BIND15933712 
Hdm2 interacts with Hdm2.BIND15916963 
MDM4DKFZp781B1423 | HDMX | MDMX | MGC132766 | MRP1Mdm4 p53 binding protein homolog (mouse)MDM2 interacts with MDM4 (MDMX).BIND10608892 
-HPRD,BioGRID10218570 |12393902 
|12483531 
Mdm2 interacts with Hdmx.BIND15916963 
MTBPMDM2BPMdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa-HPRD,BioGRID10906133 
NUMBS171numb homolog (Drosophila)-HPRD,BioGRID12646252 
PIAS1DDXBP1 | GBP | GU/RH-II | MGC141878 | MGC141879 | ZMIZ3protein inhibitor of activated STAT, 1-HPRD12393906 
PJA1RNF70praja 1-HPRD10722742 
PMLMYL | PP8675 | RNF71 | TRIM19promyelocytic leukemiaPML interacts with Mdm2.BIND15195100 
-HPRD,BioGRID12759344 |12915590 
|14507915 |15195100 
PSMD10dJ889N15.2 | p28proteasome (prosome, macropain) 26S subunit, non-ATPase, 10An unspecified isoform of gankyrin interacts with Mdm2.BIND16023600 
RB1OSRC | RB | p105-Rb | pRb | pp110retinoblastoma 1-HPRD,BioGRID7791904|10078201 |10721693 
Rb interacts with Mdm2.BIND15577944 
Rb interacts with MDM2.BIND15485814 
RBL2FLJ26459 | P130 | Rb2retinoblastoma-like 2 (p130)p130 interacts with Mdm2.BIND15577944 
RPL11GIG34ribosomal protein L11Affinity Capture-MS
Affinity Capture-Western		BioGRID14612427 
L11 interacts with Hdm2.BIND12842086 
RPL5MGC117339 | MSTP030ribosomal protein L5-HPRD,BioGRID7935455 |14612427 
SP1-Sp1 transcription factorSP1 interacts with the MDM2 intronic promoter.BIND15550242 
SUMO1DAP-1 | GMP1 | OFC10 | PIC1 | SENP2 | SMT3 | SMT3C | SMT3H3 | SUMO-1 | UBL1SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)-HPRD10892746 
TAF1BA2R | CCG1 | CCGS | DYT3 | KAT4 | N-TAF1 | NSCL2 | OF | P250 | TAF2A | TAFII250TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa-HPRD,BioGRID9388200 
TBPGTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIIDTATA box binding proteinReconstituted ComplexBioGRID9271120 |9388200 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53TP53 (p53) interacts with the MDM2-promoter.BIND15735750 
An unspecified isoform of HDM2 interacts with p53. This interaction was modelled on a demonstrated interaction between human HDM2 and p53 from an unspecified species.BIND15950904 
Affinity Capture-Western
Biochemical Activity
Co-fractionation
Reconstituted Complex		BioGRID7686617 |9271120 
|9529249 |9809062 
|10722742 |10766163 
|10892746 |11709713 
|12208736 |12426395 
|12620407 |12915590 
|14612427 |14671306 
p53 interacts with Mdm2.BIND15577944 
HDM-2 interacts with p53BIND15558054 
p53 interacts with mdm2 promoter.BIND16009130 
MDM2 (HDM2) interacts with TP53 (p53). This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species, and human TP53.BIND15688025 
Mdm2 ubiquitinates p53.BIND10822382 
Mdm2 interacts with p53.BIND11046142 
hdm2 interacts with p53. This interaction was modeled on a demonstrated interaction between hdm2 and p53 both from an unspecified species.BIND9223638 
Mdm2 interacts with p53.BIND16023600 
An unspecified isoform of MDM2 interacts with and ubiquitinates p53. This interaction was modeled on a demonstrated interaction between MDM2 from an unspecified species and human p53.BIND15933712 
Mdm2 interacts with and ubiquitinates p53.BIND15280377 
p53 interacts with Mdm2.BIND11597128 
Mdm2 interacts with and ubiquitinates p53BIND14671306 
p53 interacts with unspecified isoform of Mdm2.BIND15824742 
p53 interacts with and is ubiquitinated by Mdm2.BIND15577914 
-HPRD7686617 |8058315 
|10721693 |11709713 
|12372616 
Hdm2 interacts with p53.BIND15210108 
An unspecifed isoform of Mdm2 interacts with p53.BIND15867431 
Mdm2 ubiquitinates p53. This interaction was modeled on a demonstrated interaction between mouse Mdm2 and human p53.BIND15242646 
Mdm2 interacts with p53.BIND10562557 
p53 interacts with mdm2. This interaction was modelled on a demonstrated interaction between human p53 and mdm2 from an unspecified species.BIND10781812 
p53 interacts with the hdm2 promoter.BIND15525514 
An unspecified isoform of Mdm2 ubiquitinates p53. This interaction was modeled on a demonstrated interaction between Mdm2 and p53 both from an unspecified species.BIND15963787 
TP73P73tumor protein p73-HPRD,BioGRID10207051 
TSG101TSG10 | VPS23tumor susceptibility gene 101-HPRD,BioGRID11172000 
UBE2AHHR6A | RAD6A | UBC2ubiquitin-conjugating enzyme E2A (RAD6 homolog)Affinity Capture-WesternBioGRID12640129 
USP7HAUSP | TEF1ubiquitin specific peptidase 7 (herpes virus-associated)Mdm2 interacts with HAUSP. This interaction was modeled on a demonstrated interaction between Mdm2 from an unspecified species and human HAUSP.BIND15916963 
YY1DELTA | INO80S | NF-E1 | UCRBP | YIN-YANG-1YY1 transcription factorYY1 interacts with Hdm2.BIND15210108 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CELL_CYCLE 12884All SZGR genes in this pathway
KEGG_P53_SIGNALING_PATHWAY 6945All SZGR genes in this pathway
KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 13898All SZGR genes in this pathway
KEGG_ENDOCYTOSIS 183132All SZGR genes in this pathway
KEGG_PATHWAYS_IN_CANCER 328259All SZGR genes in this pathway
KEGG_GLIOMA 6556All SZGR genes in this pathway
KEGG_PROSTATE_CANCER 8975All SZGR genes in this pathway
KEGG_MELANOMA 7157All SZGR genes in this pathway
KEGG_BLADDER_CANCER 4233All SZGR genes in this pathway
KEGG_CHRONIC_MYELOID_LEUKEMIA 7359All SZGR genes in this pathway
BIOCARTA_ATM_PATHWAY 2016All SZGR genes in this pathway
BIOCARTA_G2_PATHWAY 2420All SZGR genes in this pathway
BIOCARTA_CTCF_PATHWAY 2318All SZGR genes in this pathway
BIOCARTA_HIVNEF_PATHWAY 5843All SZGR genes in this pathway
BIOCARTA_P53HYPOXIA_PATHWAY 2321All SZGR genes in this pathway
BIOCARTA_P53_PATHWAY 1613All SZGR genes in this pathway
BIOCARTA_ARF_PATHWAY 1713All SZGR genes in this pathway
SA_G1_AND_S_PHASES 1510All SZGR genes in this pathway
PID_ERBB4_PATHWAY 3832All SZGR genes in this pathway
PID_P73PATHWAY 7959All SZGR genes in this pathway
PID_ATR_PATHWAY 3925All SZGR genes in this pathway
PID_ATM_PATHWAY 3425All SZGR genes in this pathway
PID_REG_GR_PATHWAY 8260All SZGR genes in this pathway
PID_RANBP2_PATHWAY 1111All SZGR genes in this pathway
PID_P53_DOWNSTREAM_PATHWAY 13794All SZGR genes in this pathway
PID_AR_TF_PATHWAY 5338All SZGR genes in this pathway
PID_DELTA_NP63_PATHWAY 4734All SZGR genes in this pathway
PID_AURORA_A_PATHWAY 3120All SZGR genes in this pathway
PID_TAP63_PATHWAY 5440All SZGR genes in this pathway
PID_P53_REGULATION_PATHWAY 5950All SZGR genes in this pathway
PID_RB_1PATHWAY 6546All SZGR genes in this pathway
REACTOME_SIGNALLING_BY_NGF 217167All SZGR genes in this pathway
REACTOME_SIGNALING_BY_SCF_KIT 7859All SZGR genes in this pathway
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB4 9067All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ERBB2 10178All SZGR genes in this pathway
REACTOME_SIGNALING_BY_EGFR_IN_CANCER 10980All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING 3828All SZGR genes in this pathway
REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING 4434All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 9766All SZGR genes in this pathway
REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 12690All SZGR genes in this pathway
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE 137105All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 12788All SZGR genes in this pathway
REACTOME_PI3K_AKT_ACTIVATION 3829All SZGR genes in this pathway
REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL 1210All SZGR genes in this pathway
REACTOME_GAB1_SIGNALOSOME 3829All SZGR genes in this pathway
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 186155All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 137110All SZGR genes in this pathway
REACTOME_CELL_CYCLE_CHECKPOINTS 12470All SZGR genes in this pathway
REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE 5735All SZGR genes in this pathway
REACTOME_SIGNALING_BY_PDGF 12293All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 9576All SZGR genes in this pathway
REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS 2823All SZGR genes in this pathway
REACTOME_PI_3K_CASCADE 5639All SZGR genes in this pathway
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR 10074All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
REACTOME_PIP3_ACTIVATES_AKT_SIGNALING 2920All SZGR genes in this pathway
REACTOME_SIGNALING_BY_FGFR 11280All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
NOJIMA_SFRP2_TARGETS_DN 2518All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_DN 240171All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_DN 228137All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
DUTTA_APOPTOSIS_VIA_NFKB 3325All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_2 12792All SZGR genes in this pathway
RASHI_NFKB1_TARGETS 1918All SZGR genes in this pathway
LI_LUNG_CANCER 4130All SZGR genes in this pathway
SCHAVOLT_TARGETS_OF_TP53_AND_TP63 1612All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
HEIDENBLAD_AMPLIFIED_IN_SOFT_TISSUE_CANCER 137All SZGR genes in this pathway
KOMMAGANI_TP63_GAMMA_TARGETS 97All SZGR genes in this pathway
HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 1812All SZGR genes in this pathway
SHI_SPARC_TARGETS_UP 2417All SZGR genes in this pathway
AMUNDSON_DNA_DAMAGE_RESPONSE_TP53 169All SZGR genes in this pathway
SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS 3727All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP 227137All SZGR genes in this pathway
MANN_RESPONSE_TO_AMIFOSTINE_UP 2012All SZGR genes in this pathway
CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN 3831All SZGR genes in this pathway
PUJANA_BREAST_CANCER_LIT_INT_NETWORK 10173All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NAKAYAMA_FRA2_TARGETS 4327All SZGR genes in this pathway
ROPERO_HDAC2_TARGETS 11471All SZGR genes in this pathway
SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP 139All SZGR genes in this pathway
FRIDMAN_SENESCENCE_UP 7760All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_12Q13_Q21_AMPLICON 4621All SZGR genes in this pathway
TCGA_GLIOBLASTOMA_COPY_NUMBER_UP 7536All SZGR genes in this pathway
ONDER_CDH1_TARGETS_1_UP 14085All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_UP 197110All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_UP 205126All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
HOFMANN_CELL_LYMPHOMA_UP 5035All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP 214133All SZGR genes in this pathway
MA_MYELOID_DIFFERENTIATION_UP 3929All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_CISPLATIN 2211All SZGR genes in this pathway
ONGUSAHA_TP53_TARGETS 3823All SZGR genes in this pathway
SIMBULAN_PARP1_TARGETS_UP 3123All SZGR genes in this pathway
INGA_TP53_TARGETS 1713All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_METHOTREXATE_UP 2616All SZGR genes in this pathway
ZHANG_PROLIFERATING_VS_QUIESCENT 5141All SZGR genes in this pathway
CHIBA_RESPONSE_TO_TSA_DN 2314All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C3 3624All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_DN 160101All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MCGOWAN_RSP6_TARGETS_UP 1812All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
KUMAMOTO_RESPONSE_TO_NUTLIN_3A_UP 95All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
TAVAZOIE_METASTASIS 10868All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN 180116All SZGR genes in this pathway
LIU_TOPBP1_TARGETS 168All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_36HR 2923All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
DELACROIX_RAR_BOUND_ES 462273All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_2HR_UP 5333All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_UP 16697All SZGR genes in this pathway
GHANDHI_DIRECT_IRRADIATION_UP 11068All SZGR genes in this pathway
WARTERS_RESPONSE_TO_IR_SKIN 8344All SZGR genes in this pathway
WARTERS_IR_RESPONSE_5GY 4723All SZGR genes in this pathway


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