Gene Page: NEUROD2

Summary
GeneID  4761
Symbol  NEUROD2
Synonyms  MGC26304|NDRF|bHLHa1
Description  neurogenic differentiation 2
See related  HGNC:7763|MIM:601725|Ensembl:ENSG00000171532|HPRD:03429|
Locus tag  -
Gene type  protein-coding
Map location  17q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HYAL20.680.71
CDC42EP40.630.66
SLC39A10.630.64
MKNK20.630.60
CORO1B0.620.63
SEMA4B0.610.65
XKR80.600.62
MAFF0.600.62
RBM380.600.60
FADS20.600.62
Top 10 negatively co-expressed genes
AC104794.1-0.52-0.49
RERGL-0.51-0.50
SYCP3-0.50-0.42
USMG5-0.48-0.52
C5orf53-0.47-0.46
PIGB-0.47-0.49
SATL1-0.44-0.43
UROS-0.44-0.41
MAEL-0.44-0.46
LY96-0.43-0.44
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS8816493 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0048666neuron developmentIEAneuron (GO term level: 9)-
GO:0007399nervous system developmentTASneurite (GO term level: 5)8816493 
GO:0001662behavioral fear responseIEA-
GO:0006357regulation of transcription from RNA polymerase II promoterTAS8816493 
GO:0008306associative learningIEA-
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PKN1DBK | MGC46204 | PAK1 | PKN | PKN-ALPHA | PRK1 | PRKCL1protein kinase N1-HPRD,BioGRID10640683 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q11_Q21_AMPLICON 13378All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_UP 10072All SZGR genes in this pathway
CADWELL_ATG16L1_TARGETS_UP 9356All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p15091515m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-1377627691A,m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-1538458521A,m8hsa-miR-153UUGCAUAGUCACAAAAGUGA
miR-17-5p/20/93.mr/106/519.d939945m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-185208214m8hsa-miR-185brainUGGAGAGAAAGGCAGUUC
miR-210117111781A,m8hsa-miR-210CUGUGCGUGUGACAGCGGCUGA
miR-2199929981Ahsa-miR-219brainUGAUUGUCCAAACGCAAUUCU
miR-331173179m8hsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-34/44910271033m8hsa-miR-34abrainUGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34cAGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449bAGGCAGUGUAUUGUUAGCUGGC
miR-4488468521Ahsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-450150915151Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
miR-496166016661Ahsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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