Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: NHLH1

Summary

GeneID

4807

Symbol

NHLH1

Synonyms

HEN1|NSCL|NSCL1|bHLHa35

Description

nescient helix loop helix 1

Locus tag

Gene type

protein-coding

Map location

1q22

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00814

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

AC022532.3

0.96

0.95

MMP25

0.76

0.72

CLN3

0.73

0.71

RAMP2

0.72

0.73

PVRL2

0.72

0.68

AC100793.2

0.71

0.70

ISYNA1

0.71

0.77

STRA6

0.71

0.73

MOSPD3

0.70

CPNE2

0.70

0.64

Top 10 negatively co-expressed genes

GBP2

-0.52

-0.62

RAPGEF4

-0.52

-0.61

SEPT8

-0.51

-0.59

BCL2L2

-0.51

-0.59

CHN1

-0.50

-0.54

CCNI2

-0.50

-0.56

HLA-F

-0.50

-0.51

OMG

-0.49

-0.61

ANXA11

-0.49

-0.60

FBXO2

-0.49

-0.53

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003677

DNA binding

IEA

GO:0030528

transcription regulator activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007417

central nervous system development

TAS

Brain (GO term level: 6)

1328219

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0007275

multicellular organismal development

IEA

GO:0030154

cell differentiation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CSRP3	CLP \| CMD1M \| CMH12 \| CRP3 \| LMO4 \| MGC14488 \| MGC61993 \| MLP	cysteine and glycine-rich protein 3 (cardiac LIM protein)	-	HPRD	12878195
LMO1	MGC116692 \| RBTN1 \| RHOM1 \| TTG1	LIM domain only 1 (rhombotin 1)	-	HPRD	10603358
LMO2	RBTN2 \| RBTNL1 \| RHOM2 \| TTG2	LIM domain only 2 (rhombotin-like 1)	-	HPRD,BioGRID	12878195
TCF3	E2A \| ITF1 \| MGC129647 \| MGC129648 \| bHLHb21	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	Two-hybrid	BioGRID	12878195

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP	332	228	All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP	146	99	All SZGR genes in this pathway
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_DN	35	20	All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN	712	443	All SZGR genes in this pathway
KIM_MYC_AMPLIFICATION_TARGETS_UP	201	127	All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN	357	212	All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP	398	262	All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN	59	35	All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_PROGNOSIS_UP	47	30	All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR	532	309	All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP	98	64	All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_UP	85	50	All SZGR genes in this pathway
LEIN_CEREBELLUM_MARKERS	85	47	All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP	104	57	All SZGR genes in this pathway
MIKKELSEN_MEF_LCP_WITH_H3K27ME3	70	35	All SZGR genes in this pathway
SENGUPTA_EBNA1_ANTICORRELATED	173	85	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124/506	668	674	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	668	674	m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-17-5p/20/93.mr/106/519.d	1283	1289	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.