Gene Page: NPY1R

Summary
GeneID  4886
Symbol  NPY1R
Synonyms  NPYR
Description  neuropeptide Y receptor Y1
See related  HGNC:7956|MIM:162641|Ensembl:ENSG00000164128|HPRD:01215|
Locus tag  -
Gene type  protein-coding
Map location  4q31.3-q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FAM155B0.870.79
CBFA2T30.850.77
TNRC18B0.850.89
KIRREL0.840.84
AL139010.20.840.83
BAHCC10.830.84
ZNF512B0.820.83
CACNA1H0.820.81
ZNF7100.820.82
ZBED10.820.83
Top 10 negatively co-expressed genes
C5orf53-0.57-0.72
ACOT13-0.53-0.73
S100B-0.53-0.71
ACYP2-0.53-0.68
CA4-0.52-0.66
AF347015.31-0.52-0.72
COPZ2-0.52-0.67
HLA-F-0.52-0.60
AF347015.27-0.52-0.71
B2M-0.51-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001601peptide YY receptor activityIEA-
GO:0001602pancreatic polypeptide receptor activityIEA-
GO:0004872receptor activityIEA-
GO:0005515protein bindingIPI15231747 
GO:0004983neuropeptide Y receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007218neuropeptide signaling pathwayIEANeurotransmitter (GO term level: 8)-
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messengerTAS1317848 
GO:0008217regulation of blood pressureIEA-
GO:0007193G-protein signaling, adenylate cyclase inhibiting pathwayTAS1321422 
GO:0006006glucose metabolic processIEA-
GO:0007165signal transductionIEA-
GO:0007631feeding behaviorIEA-
GO:0007626locomotory behaviorIEA-
GO:0019233sensory perception of painIEA-
GO:0040014regulation of multicellular organism growthIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS1317848 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
LSM7YNL147WLSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
NPYPYY4neuropeptide Y-HPRD,BioGRID7559383 |9001438|12007534 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
WILCOX_RESPONSE_TO_PROGESTERONE_UP 15290All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN 1911All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_DN 203134All SZGR genes in this pathway
WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN 5529All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
STAEGE_EWING_FAMILY_TUMOR 3322All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_DN 10267All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_DN 8049All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_DN 8666All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_UP 178111All SZGR genes in this pathway
SASSON_FSH_RESPONSE 96All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 9772All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP 430288All SZGR genes in this pathway
MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP 2010All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
SMID_BREAST_CANCER_ERBB2_DN 55All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP 425298All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_DN 546362All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
MIKKELSEN_MEF_ICP_WITH_H3K4ME3_AND_H3K27ME3 3834All SZGR genes in this pathway
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN 8051All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 13785All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP 229149All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP 324193All SZGR genes in this pathway
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_3 209All SZGR genes in this pathway
PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 7645All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-21845521A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-381109010971A,m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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