Gene Page: ACO2

Summary
GeneID  50
Symbol  ACO2
Synonyms  ACONM|MGC20605|MGC33908
Description  aconitase 2, mitochondrial
See related  HGNC:118|MIM:100850|Ensembl:ENSG00000100412|HPRD:00012|
Locus tag  -
Gene type  protein-coding
Map location  22q11.2-q13.31|22q13.2|22q13.2-q13.31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ATP6AP10.910.91
SEZ6L20.890.91
CHPF0.870.90
LENG40.870.88
FAM127A0.860.87
PCYOX1L0.860.85
GRINA0.860.85
PNPLA60.860.84
CLSTN30.850.88
PTPRN20.850.86
Top 10 negatively co-expressed genes
AF347015.21-0.60-0.46
AF347015.18-0.55-0.46
MT-CO2-0.55-0.43
AC098691.2-0.54-0.49
NOSTRIN-0.53-0.42
AF347015.8-0.53-0.43
AF347015.2-0.53-0.40
AF347015.31-0.52-0.42
AF347015.33-0.52-0.41
AP002478.3-0.52-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003994aconitate hydratase activityEXP1946331 
GO:0003994aconitate hydratase activityIEA-
GO:0005506iron ion bindingIDA9630632 
GO:0016829lyase activityIEA-
GO:0046872metal ion bindingIEA-
GO:00515394 iron, 4 sulfur cluster bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006101citrate metabolic processIDA9630632 
GO:0006099tricarboxylic acid cycleIDA9630632 
GO:0006091generation of precursor metabolites and energyTAS9630632 
GO:0008152metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005739mitochondrionTAS9630632 
GO:0005759mitochondrial matrixEXP1946331 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CITRATE_CYCLE_TCA_CYCLE 3223All SZGR genes in this pathway
KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM 1612All SZGR genes in this pathway
BIOCARTA_KREB_PATHWAY 88All SZGR genes in this pathway
REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 4832All SZGR genes in this pathway
REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 14185All SZGR genes in this pathway
REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 5824All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS 518242All SZGR genes in this pathway
REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 2616All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP 13983All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 151100All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 5135All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_SUBGROUPS 3020All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C6 3927All SZGR genes in this pathway
JIANG_AGING_HYPOTHALAMUS_DN 4031All SZGR genes in this pathway
BURTON_ADIPOGENESIS_5 12678All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
JIANG_AGING_CEREBRAL_CORTEX_DN 5443All SZGR genes in this pathway
LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES 3726All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
MOOTHA_TCA 1613All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G5 128All SZGR genes in this pathway
LU_EZH2_TARGETS_UP 295155All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-203.12922981Ahsa-miR-203UGAAAUGUUUAGGACCACUAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.