Gene Page: PAFAH1B3

Summary
GeneID  5050
Symbol  PAFAH1B3
Synonyms  -
Description  platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa
See related  HGNC:8576|MIM:603074|Ensembl:ENSG00000079462|HPRD:04354|
Locus tag  -
Gene type  protein-coding
Map location  19q13.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SMAD40.960.93
STAG10.960.93
SP30.960.94
DHX90.960.93
PPM1D0.950.94
ZFP1610.950.94
HNRNPK0.950.93
SFRS10.950.94
ALDH18A10.950.93
CORO1C0.950.93
Top 10 negatively co-expressed genes
FXYD1-0.70-0.87
MT-CO2-0.70-0.86
AF347015.31-0.69-0.85
IFI27-0.69-0.86
HLA-F-0.69-0.76
AF347015.33-0.68-0.82
AF347015.27-0.67-0.82
C5orf53-0.67-0.71
PTH1R-0.67-0.75
MT-CYB-0.66-0.82
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:00038471-alkyl-2-acetylglycerophosphocholine esterase activityIEA-
GO:0005515protein bindingIPI16189514 
GO:0016788hydrolase activity, acting on ester bondsIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)7669037 
GO:0016042lipid catabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRD7BP75 | CELTIX1 | NAG4bromodomain containing 7Two-hybridBioGRID16169070 
C14orf1ERG28 | NET51chromosome 14 open reading frame 1Two-hybridBioGRID16169070 
C1orf103FLJ11269 | RIF1 | RP11-96K19.1chromosome 1 open reading frame 103Two-hybridBioGRID16169070 
C7orf64DKFZP564O0523 | DKFZp686D1651 | HSPC304chromosome 7 open reading frame 64Two-hybridBioGRID16169070 
CCDC90BMDS011 | MDS025 | MGC104239coiled-coil domain containing 90BTwo-hybridBioGRID16169070 
CHMP7MGC29816CHMP family, member 7Two-hybridBioGRID16189514 
COPS6CSN6 | MOV34-34KDCOP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)Two-hybridBioGRID16169070 
CRMP1DPYSL1 | DRP-1 | DRP1collapsin response mediator protein 1Two-hybridBioGRID16169070 
DDX24-DEAD (Asp-Glu-Ala-Asp) box polypeptide 24Two-hybridBioGRID16169070 
ECH1HPXELenoyl Coenzyme A hydratase 1, peroxisomalTwo-hybridBioGRID16169070 
EEF1A1CCS-3 | CCS3 | EEF-1 | EEF1A | EF-Tu | EF1A | FLJ25721 | GRAF-1EF | HNGC:16303 | LENG7 | MGC102687 | MGC131894 | MGC16224 | PTI1 | eEF1A-1eukaryotic translation elongation factor 1 alpha 1Two-hybridBioGRID16169070 
GAPDHG3PD | GAPD | MGC88685glyceraldehyde-3-phosphate dehydrogenaseTwo-hybridBioGRID16169070 
GBP2-guanylate binding protein 2, interferon-inducibleTwo-hybridBioGRID16169070 
GDF9-growth differentiation factor 9Two-hybridBioGRID16169070 
HSPH1DKFZp686M05240 | HSP105 | HSP105A | HSP105B | KIAA0201 | NY-CO-25heat shock 105kDa/110kDa protein 1Reconstituted ComplexBioGRID14733918 
IGSF21FLJ41177 | MGC15730immunoglobin superfamily, member 21Two-hybridBioGRID16169070 
LNX1LNX | MPDZ | PDZRN2ligand of numb-protein X 1Affinity Capture-Western
Two-hybrid
BioGRID16189514 
MED313110004H13Rik | CGI-125 | FLJ27436 | FLJ36714 | Soh1mediator complex subunit 31Two-hybridBioGRID16169070 
PAFAH1B1LIS1 | LIS2 | MDCR | MDS | PAFAHplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa-HPRD,BioGRID10727864 
PAFAH1B2-platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDaTwo-hybridBioGRID16189514 
PAFAH1B3-platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDaTwo-hybridBioGRID16189514 
PLEKHM1AP162 | B2 | KIAA0356 | OPTB6pleckstrin homology domain containing, family M (with RUN domain) member 1Two-hybridBioGRID16169070 
SDCBP2FLJ12256 | SITAC18 | ST-2syndecan binding protein (syntenin) 2Two-hybridBioGRID16189514 
SETDB1ESET | KG1T | KIAA0067 | KMT1ESET domain, bifurcated 1Two-hybridBioGRID16169070 
TLE1ESG | ESG1 | GRG1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)Two-hybridBioGRID16169070 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53Two-hybridBioGRID16169070 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2ATwo-hybridBioGRID16169070 
UNC119HRG4unc-119 homolog (C. elegans)Two-hybridBioGRID16169070 
XRCC6CTC75 | CTCBF | G22P1 | KU70 | ML8 | TLAAX-ray repair complementing defective repair in Chinese hamster cells 6Two-hybridBioGRID16169070 
ZBTB16PLZF | ZNF145zinc finger and BTB domain containing 16Two-hybridBioGRID16169070 
ZHX1-zinc fingers and homeoboxes 1Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ETHER_LIPID_METABOLISM 3315All SZGR genes in this pathway
PID_LIS1_PATHWAY 2822All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN 378231All SZGR genes in this pathway
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN 2316All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER 14073All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 229137All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
LIAO_METASTASIS 539324All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_UP 8657All SZGR genes in this pathway
MORI_MATURE_B_LYMPHOCYTE_DN 7543All SZGR genes in this pathway
YAGI_AML_FAB_MARKERS 191131All SZGR genes in this pathway
RHODES_CANCER_META_SIGNATURE 6447All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_UP 9564All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_4NQO_OR_UV 6344All SZGR genes in this pathway
KYNG_DNA_DAMAGE_DN 195135All SZGR genes in this pathway
IWANAGA_CARCINOGENESIS_BY_KRAS_UP 170107All SZGR genes in this pathway
WHITEFORD_PEDIATRIC_CANCER_MARKERS 11663All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP 1410All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP 178108All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_UP 166105All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 172107All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
QI_HYPOXIA 14096All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP 570339All SZGR genes in this pathway
ALFANO_MYC_TARGETS 239156All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_DN 428246All SZGR genes in this pathway


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