Gene Page: IL21R

Summary
GeneID  50615
Symbol  IL21R
Synonyms  MGC10967|NILR
Description  interleukin 21 receptor
See related  HGNC:6006|MIM:605383|Ensembl:ENSG00000103522|HPRD:05649|
Locus tag  -
Gene type  protein-coding
Map location  16p11
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001532interleukin-21 receptor activityNAS11081504 
GO:0004872receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030101natural killer cell activationNAS11081504 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneNAS11081504 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
IL2IL-2 | TCGF | lymphokineinterleukin 2Affinity Capture-WesternBioGRID11418623 
IL21IL-21 | Za11interleukin 21-HPRD,BioGRID11418623 
JAK1JAK1A | JAK1B | JTK3Janus kinase 1 (a protein tyrosine kinase)Affinity Capture-WesternBioGRID11016959 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 267161All SZGR genes in this pathway
KEGG_JAK_STAT_SIGNALING_PATHWAY 155105All SZGR genes in this pathway
GARY_CD5_TARGETS_UP 473314All SZGR genes in this pathway
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP 158103All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
PATIL_LIVER_CANCER 747453All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
BALLIF_DEVELOPMENTAL_DISABILITY_P16_P12_DELETION 138All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_8 3628All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_UP 8961All SZGR genes in this pathway
HELLER_HDAC_TARGETS_DN 292189All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 10963All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
GAURNIER_PSMD4_TARGETS 7355All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
GRESHOCK_CANCER_COPY_NUMBER_UP 323240All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN 245150All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway


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