Gene Page: PHYH

Summary
GeneID  5264
Symbol  PHYH
Synonyms  LN1|LNAP1|PAHX|PHYH1|RD
Description  phytanoyl-CoA 2-hydroxylase
See related  HGNC:8940|MIM:602026|Ensembl:ENSG00000107537|HPRD:03609|
Locus tag  RP11-24J20.1
Gene type  protein-coding
Map location  10p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRIM460.930.96
GPRIN10.930.96
PACS10.930.96
SARM10.920.96
DTX10.920.93
FAM171A20.920.94
STRN40.910.95
SRD5A10.910.93
KCTD130.910.93
GRAMD1A0.910.93
Top 10 negatively co-expressed genes
MT-CO2-0.77-0.85
AF347015.31-0.77-0.84
AF347015.33-0.76-0.83
AF347015.27-0.76-0.83
MT-CYB-0.74-0.82
S100B-0.74-0.81
AF347015.8-0.74-0.84
AC021016.1-0.72-0.84
FXYD1-0.72-0.79
HLA-F-0.71-0.73
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0005515protein bindingIPI17353931 
GO:0009055electron carrier activityTAS8954107 
GO:0031418L-ascorbic acid bindingIEA-
GO:0048244phytanoyl-CoA dioxygenase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)9326940 
GO:0007605sensory perception of soundIEA-
GO:0007601visual perceptionIEA-
GO:0006629lipid metabolic processTAS8954107 
GO:0050896response to stimulusIEA-
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005777peroxisomeTAS8954107 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
COPS3SGN3COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)Affinity Capture-MSBioGRID17353931 
F8AHF | DXS1253E | F8B | F8C | FVIII | HEMAcoagulation factor VIII, procoagulant component-HPRD,BioGRID11574539 
FKBP4FKBP52 | FKBP59 | HBI | Hsp56 | PPIase | p52FK506 binding protein 4, 59kDa-HPRD,BioGRID10051602 
MAGEA11MAGE-11 | MAGE11 | MAGEA-11 | MGC10511melanoma antigen family A, 11Two-hybridBioGRID16189514 
PEX7PTS2R | RCDP1 | RDperoxisomal biogenesis factor 7-HPRD,BioGRID9326939 
PHYHLN1 | LNAP1 | PAHX | PHYH1 | RDphytanoyl-CoA 2-hydroxylase-HPRD10686344 
PHYHIPDYRK1AP3 | KIAA0273 | PAHX-AP | PAHXAP1phytanoyl-CoA 2-hydroxylase interacting protein-HPRD10686344 
TOM1L1OK/KNS-CL.3 | SRCASMtarget of myb1 (chicken)-like 1Two-hybridBioGRID16169070 
WDR8FLJ20430 | MGC99569WD repeat domain 8Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PEROXISOME 7847All SZGR genes in this pathway
REACTOME_PEROXISOMAL_LIPID_METABOLISM 2111All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
HOLLMANN_APOPTOSIS_VIA_CD40_DN 267178All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
HOEBEKE_LYMPHOID_STEM_CELL_DN 8659All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
DITTMER_PTHLH_TARGETS_UP 11268All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_UP 167All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
LANDIS_BREAST_CANCER_PROGRESSION_DN 7043All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_65_DN 3722All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_DN 14993All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
YORDY_RECIPROCAL_REGULATION_BY_ETS1_AND_SP100_DN 8748All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
NELSON_RESPONSE_TO_ANDROGEN_UP 8661All SZGR genes in this pathway
LEE_LIVER_CANCER_DENA_DN 7445All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC 5032All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_DN 15093All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_DN 14588All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_DN 215132All SZGR genes in this pathway
GAJATE_RESPONSE_TO_TRABECTEDIN_UP 6745All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 163113All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
CHUNG_BLISTER_CYTOTOXICITY_UP 13484All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN 159105All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_UP 418282All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN 245150All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
ELLWOOD_MYC_TARGETS_DN 4027All SZGR genes in this pathway
ROME_INSULIN_TARGETS_IN_MUSCLE_UP 442263All SZGR genes in this pathway
YAGI_AML_WITH_T_9_11_TRANSLOCATION 13087All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_DN 210141All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
DURAND_STROMA_NS_UP 162103All SZGR genes in this pathway


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