Gene Page: PLCD1

Summary
GeneID  5333
Symbol  PLCD1
Synonyms  -
Description  phospholipase C, delta 1
See related  HGNC:9060|MIM:602142|Ensembl:ENSG00000187091|HPRD:09073|
Locus tag  -
Gene type  protein-coding
Map location  3p22-p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PCTK30.940.92
ATPGD10.930.92
SHROOM10.920.93
SEMA3B0.920.89
TMEM63A0.910.94
ABCA20.900.74
TMC60.900.89
UAP1L10.900.93
C11orf90.900.91
CD220.900.91
Top 10 negatively co-expressed genes
POLB-0.55-0.79
MED19-0.54-0.74
FRG1-0.53-0.75
STMN1-0.53-0.73
ALKBH2-0.52-0.76
IFT52-0.52-0.74
TRNAU1AP-0.52-0.72
NR2C2AP-0.52-0.75
ING4-0.51-0.72
RARS2-0.51-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0004435phosphoinositide phospholipase C activityIEA-
GO:0004435phosphoinositide phospholipase C activityTAS9588182 
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001525angiogenesisIEA-
GO:0001890placenta developmentIEA-
GO:0016042lipid catabolic processIEA-
GO:0007242intracellular signaling cascadeIEA-
GO:0006644phospholipid metabolic processTAS9588182 
GO:0006629lipid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolIEA-
GO:0005737cytoplasmIDA15702972 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GAP43B-50 | PP46growth associated protein 43Affinity Capture-WesternBioGRID12805215 
TGM2G-ALPHA-h | GNAH | TG2 | TGCtransglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)-HPRD,BioGRID9512491 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_INOSITOL_PHOSPHATE_METABOLISM 5442All SZGR genes in this pathway
KEGG_CALCIUM_SIGNALING_PATHWAY 178134All SZGR genes in this pathway
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 7656All SZGR genes in this pathway
KIM_WT1_TARGETS_12HR_UP 162116All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
PEREZ_TP53_AND_TP63_TARGETS 205145All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
GOLDRATH_IMMUNE_MEMORY 6542All SZGR genes in this pathway
URS_ADIPOCYTE_DIFFERENTIATION_UP 7451All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_DN 178121All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C7 6844All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
ZHANG_TLX_TARGETS_UP 10878All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED 536296All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
FOSTER_KDM1A_TARGETS_DN 211119All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1911932001A,m8hsa-miR-191brainCAACGGAAUCCCAAAAGCAGCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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