Gene Page: CLIC5

Summary
GeneID  53405
Symbol  CLIC5
Synonyms  CLIC5B|FLJ90663|MST130|MSTP130|dJ447E21.4
Description  chloride intracellular channel 5
See related  HGNC:13517|MIM:607293|Ensembl:ENSG00000112782|HPRD:06292|
Locus tag  RP11-546O15.1
Gene type  protein-coding
Map location  6p21.1-p12.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10793131 
GO:0005244voltage-gated ion channel activityIEA-
GO:0005247voltage-gated chloride channel activityIEA-
GO:0031404chloride ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008104protein localizationIEA-
GO:0007605sensory perception of soundIEA-
GO:0007565female pregnancyTAS10793131 
GO:0006821chloride transportIDA10793131 
GO:0006811ion transportIEA-
GO:0050885neuromuscular process controlling balanceIEA-
GO:0060088auditory receptor cell stereocilium organizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005813centrosomeIEA-
GO:0005626insoluble fractionIDA10793131 
GO:0005737cytoplasmIEA-
GO:0016020membraneIEA-
GO:0015629actin cytoskeletonIDA10793131 
GO:0032420stereociliumIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EZRCVIL | CVL | DKFZp762H157 | FLJ26216 | MGC1584 | VIL2ezrin-HPRD,BioGRID10793131 
GSNDKFZp313L0718gelsolin (amyloidosis, Finnish type)-HPRD10793131 
IQGAP1HUMORFA01 | KIAA0051 | SAR1 | p195IQ motif containing GTPase activating protein 1-HPRD10793131 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
THUM_SYSTOLIC_HEART_FAILURE_UP 423283All SZGR genes in this pathway
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN 6743All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
CUI_TCF21_TARGETS_DN 3123All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
BOQUEST_STEM_CELL_DN 216143All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED 8050All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_DN 10971All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-122441944261A,m8hsa-miR-122aUGGAGUGUGACAAUGGUGUUUGU
miR-1827617671Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-26124712531Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-967617671Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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