Gene Page: TREM2

Summary
GeneID  54209
Symbol  TREM2
Synonyms  TREM-2|Trem2a|Trem2b|Trem2c
Description  triggering receptor expressed on myeloid cells 2
See related  HGNC:17761|MIM:605086|Ensembl:ENSG00000095970|HPRD:05473|
Locus tag  -
Gene type  protein-coding
Map location  6p21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityTAS10799849 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006959humoral immune responseTAS10799849 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
TYROBPDAP12 | KARAP | PLOSLTYRO protein tyrosine kinase binding protein-HPRD12080485 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_OTHER_SEMAPHORIN_INTERACTIONS 1514All SZGR genes in this pathway
REACTOME_SEMAPHORIN_INTERACTIONS 6853All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN 14290All SZGR genes in this pathway
DELYS_THYROID_CANCER_UP 443294All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_DN 185115All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN 165107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_DN 180110All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_UP 165100All SZGR genes in this pathway
LIAN_LIPA_TARGETS_6M 7447All SZGR genes in this pathway
LIAN_LIPA_TARGETS_3M 5936All SZGR genes in this pathway
HENDRICKS_SMARCA4_TARGETS_DN 5334All SZGR genes in this pathway
NIELSEN_SCHWANNOMA_UP 1816All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
VILIMAS_NOTCH1_TARGETS_DN 2012All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_UP 10575All SZGR genes in this pathway
MIKKELSEN_ES_LCP_WITH_H3K27ME3 148All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway


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