Gene Page: PLEKHA5

Summary
GeneID  54477
Symbol  PLEKHA5
Synonyms  FLJ10667|FLJ31492|KIAA1686|PEPP2
Description  pleckstrin homology domain containing, family A member 5
See related  HGNC:30036|MIM:607770|Ensembl:ENSG00000052126|HPRD:09684|
Locus tag  -
Gene type  protein-coding
Map location  12p12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0311 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005545phosphatidylinositol bindingNAS11001876 
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI16713569 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0008150biological_processND-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
LSM4YER112WLSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP 177110All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_DN 167100All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_UP 316190All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_DN 781465All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
CHOI_ATL_STAGE_PREDICTOR 4424All SZGR genes in this pathway
KIM_MYCN_AMPLIFICATION_TARGETS_DN 10359All SZGR genes in this pathway
RICKMAN_METASTASIS_UP 344180All SZGR genes in this pathway
GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 6345All SZGR genes in this pathway
GOLDRATH_IMMUNE_MEMORY 6542All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_DN 2915All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR 681420All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP 17496All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP 338225All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN 245150All SZGR genes in this pathway
WENDT_COHESIN_TARGETS_UP 3319All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
STAMBOLSKY_TARGETS_OF_MUTATED_TP53_UP 4935All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_UP 13993All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_2_DN 336211All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1377007061Ahsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-183499505m8hsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-3201741811A,m8hsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-376971041A,m8hsa-miR-376aAUCAUAGAGGAAAAUCCACGU
hsa-miR-376bAUCAUAGAGGAAAAUCCAUGUU
miR-4104784841Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-496784790m8hsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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