Gene Page: NAGK

Summary
GeneID  55577
Symbol  NAGK
Synonyms  GNK|HSA242910
Description  N-acetylglucosamine kinase
See related  HGNC:17174|MIM:606828|Ensembl:ENSG00000124357|HPRD:08441|
Locus tag  -
Gene type  protein-coding
Map location  2p13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.1428 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
VIL20.730.74
APPL20.700.66
AL161668.20.690.70
PAX60.690.59
HDAC10.690.61
NFATC40.690.65
SMO0.680.72
TP530.680.63
TRIP100.670.59
GPR1250.670.67
Top 10 negatively co-expressed genes
MCHR2-0.45-0.50
PRKCB-0.44-0.45
GABRA4-0.44-0.51
SERPINI1-0.44-0.45
RXFP1-0.43-0.48
NRSN1-0.43-0.45
CHN1-0.43-0.41
KCNIP4-0.43-0.43
RGS4-0.43-0.43
KIAA1107-0.42-0.46
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIPI15231747 |16189514 
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
GO:0016301kinase activityIEA-
GO:0045127N-acetylglucosamine kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006051N-acetylmannosamine metabolic processTAS10824116 
GO:0006044N-acetylglucosamine metabolic processTAS10824116 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DACH1DACH | FLJ10138dachshund homolog 1 (Drosophila)Two-hybridBioGRID16189514 
FLJ25770MGC35086hypothetical protein FLJ25770Two-hybridBioGRID16189514 
LNX1LNX | MPDZ | PDZRN2ligand of numb-protein X 1Affinity Capture-Western
Two-hybrid		BioGRID16189514 
LSM8YJR022WLSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)-HPRD,BioGRID15231747 
NAGKGNK | HSA242910N-acetylglucosamine kinaseTwo-hybridBioGRID16189514 
STK16FLJ39635 | KRCT | MPSK | PKL12 | TSF1serine/threonine kinase 16Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID11741987 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 4430All SZGR genes in this pathway
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP 205140All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_UP 380236All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_UP 14699All SZGR genes in this pathway
BIDUS_METASTASIS_DN 16193All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_CD2_UP 4532All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_DN 314188All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
SAGIV_CD24_TARGETS_DN 4626All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
IVANOVSKA_MIR106B_TARGETS 9056All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-17-5p/20/93.mr/106/519.d1141211A,m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.