Gene Page: EXOC2

Summary
GeneID  55770
Symbol  EXOC2
Synonyms  FLJ11026|SEC5|SEC5L1|Sec5p
Description  exocyst complex component 2
See related  HGNC:24968|Ensembl:ENSG00000112685|HPRD:11544|
Locus tag  RP11-164H16.2
Gene type  protein-coding
Map location  6p25.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0159 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
RRM10.950.91
TRIP130.950.88
LMNB10.940.89
DNA20.940.84
NUP2050.940.89
MCM40.930.90
RCC10.920.87
NUP1070.920.87
BUD130.920.90
EZH20.920.78
Top 10 negatively co-expressed genes
HLA-F-0.67-0.81
FBXO2-0.67-0.71
C5orf53-0.66-0.74
AIFM3-0.65-0.77
LHPP-0.64-0.64
ALDOC-0.64-0.71
AF347015.27-0.64-0.87
AF347015.31-0.63-0.87
PTH1R-0.63-0.71
S100B-0.63-0.81
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI12459492 
GO:0017160Ral GTPase bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006887exocytosisIEA-
GO:0015031protein transportIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EXOC3SEC6 | SEC6L1 | Sec6pexocyst complex component 3-HPRD14525976 
EXOC72-5-3p | DKFZp686J04253 | EX070 | EXO70 | EXOC1 | Exo70p | FLJ40965 | FLJ46415 | YJL085Wexocyst complex component 7-HPRD14525976 
EXOC8EXO84 | Exo84p | SEC84exocyst complex component 8-HPRD,BioGRID14525976 
RALAMGC48949 | RALv-ral simian leukemia viral oncogene homolog A (ras related)-HPRD,BioGRID12839989 
-HPRD11744922 |12624092 
|14525976 
RalA interacts with Sec5. This interaction was modelled on a demonstrated interaction between human RalA and Sec5 from an unspecified species.BIND15920473 
RALB-v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)Two-hybridBioGRID14525976 
SERGEFDELGEF | Gnefrsecretion regulating guanine nucleotide exchange factor-HPRD,BioGRID12459492 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_INSULIN_PATHWAY 4532All SZGR genes in this pathway
PID_ARF6_TRAFFICKING_PATHWAY 4934All SZGR genes in this pathway
REACTOME_DIABETES_PATHWAYS 13391All SZGR genes in this pathway
REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING 2115All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_UP 3320All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_24HR_5_DN 5935All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
GRADE_COLON_AND_RECTAL_CANCER_UP 285167All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP 11370All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway


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