Gene Page: TRPC7

Summary
GeneID  57113
Symbol  TRPC7
Synonyms  TRP7
Description  transient receptor potential cation channel, subfamily C, member 7
See related  HGNC:20754|Ensembl:ENSG00000069018|HPRD:18228|
Locus tag  -
Gene type  protein-coding
Map location  5q31.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIPI15757897 
GO:0005262calcium channel activityIEA-
GO:0005216ion channel activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006816calcium ion transportIEA-
GO:0006811ion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ITPR3FLJ36205 | IP3R | IP3R3inositol 1,4,5-triphosphate receptor, type 3Reconstituted ComplexBioGRID11290752 
MX1IFI-78K | IFI78 | MX | MxAmyxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)MxA interacts with TRPC7. This interaction was modeled on a demonstrated interaction between human MxA and TRPC7 from unspecified species.BIND15757897 
TRPC3TRP3transient receptor potential cation channel, subfamily C, member 3FRETBioGRID12032305 
TRPC6FLJ11098 | FLJ14863 | FSGS2 | TRP6transient receptor potential cation channel, subfamily C, member 6FRETBioGRID12032305 
TRPC7TRP7transient receptor potential cation channel, subfamily C, member 7FRETBioGRID12032305 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS 106All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS 2517All SZGR genes in this pathway
REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING 118All SZGR genes in this pathway
REACTOME_NETRIN1_SIGNALING 4130All SZGR genes in this pathway
REACTOME_PLATELET_HOMEOSTASIS 7849All SZGR genes in this pathway
REACTOME_PLATELET_CALCIUM_HOMEOSTASIS 1810All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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