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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CNOT6

Summary

GeneID

57472

Symbol

CNOT6

Synonyms

CCR4|KIAA1194

Description

CCR4-NOT transcription complex, subunit 6

Locus tag

Gene type

protein-coding

Map location

5q35.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.0276

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SACM1L

0.87

0.84

NDUFS1

0.86

0.82

SENP2

0.85

0.82

SLC25A40

0.85

0.83

C2orf30

0.85

0.81

CHM

0.84

FAM179B

0.84

0.81

FAR1

0.84

0.83

DDHD2

0.84

0.80

DPP8

0.83

0.81

Top 10 negatively co-expressed genes

IL32

-0.49

-0.43

CLEC3B

-0.47

-0.54

AF347015.21

-0.45

-0.29

C16orf74

-0.42

-0.39

AF347015.18

-0.42

-0.29

C1orf61

-0.41

-0.46

FAM159B

-0.40

-0.39

CSAG1

-0.40

-0.34

CLDN5

-0.39

-0.37

AC098691.2

-0.39

-0.31

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000287

magnesium ion binding

IEA

GO:0003723

RNA binding

IEA

GO:0005515

protein binding

IEA

GO:0004527

exonuclease activity

IEA

GO:0016787

hydrolase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CNOT7	CAF1 \| hCAF-1	CCR4-NOT transcription complex, subunit 7	-	HPRD	10637334
CNOT8	CAF1 \| CALIF \| POP2 \| hCAF1	CCR4-NOT transcription complex, subunit 8	-	HPRD	10637334

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_RNA_DEGRADATION	59	37	All SZGR genes in this pathway
REACTOME_DEADENYLATION_OF_MRNA	22	14	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_MRNA	284	128	All SZGR genes in this pathway
REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY	48	29	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_RNA	330	155	All SZGR genes in this pathway
UDAYAKUMAR_MED1_TARGETS_UP	135	82	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	770	415	All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP	566	371	All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED	728	415	All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_UP	425	253	All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP	605	377	All SZGR genes in this pathway
PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN	157	106	All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP	116	87	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_UP	279	155	All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN	784	464	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-10	3699	3705	m8	hsa-miR-10a	UACCCUGUAGAUCCGAAUUUGUG
miR-10	3699	3705	m8	hsa-miR-10b	UACCCUGUAGAACCGAAUUUGU
miR-128	933	939	m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
				hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
				hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
				hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-130/301	616	622	m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
				hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-148/152	3482	3488	m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-17-5p/20/93.mr/106/519.d	3043	3049	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-182	3991	3998	1A,m8	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-19	615	621	m8	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	615	621	m8	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-193	356	363	1A,m8	hsa-miR-193a	AACUGGCCUACAAAGUCCCAG
miR-193	356	363	1A,m8	hsa-miR-193b	AACUGGCCCUCAAAGUCCCGCUUU
miR-199	3484	3490	1A	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	3484	3490	1A	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-200bc/429	3363	3369	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-21	770	776	m8	hsa-miR-21^brain	UAGCUUAUCAGACUGAUGUUGA
miR-21	770	776	m8	hsa-miR-590	GAGCUUAUUCAUAAAAGUGCAG
miR-24	176	182	m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-29	155	161	1A	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-30-5p	3499	3505	m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-320	2236	2242	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-329	213	219	m8	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU
miR-339	203	210	1A,m8	hsa-miR-339	UCCCUGUCCUCCAGGAGCUCA
miR-34/449	965	971	m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-342	1032	1038	1A	hsa-miR-342^brain	UCUCACACAGAAAUCGCACCCGUC
miR-34b	966	972	m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-377	1961	1967	1A	hsa-miR-377	AUCACACAAAGGCAACUUUUGU
miR-381	453	459	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-382	727	733	1A	hsa-miR-382^brain	GAAGUUGUUCGUGGUGGAUUCG
miR-410	3693	3699	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-433-3p	2017	2023	m8	hsa-miR-433^brain	AUCAUGAUGGGCUCCUCGGUGU
miR-485-3p	143	149	1A	hsa-miR-485-3p	GUCAUACACGGCUCUCCUCUCU
miR-493-5p	827	833	m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-494	3762	3768	1A	hsa-miR-494^brain	UGAAACAUACACGGGAAACCUCUU
miR-494	3762	3768	1A	hsa-miR-494^brain	UGAAACAUACACGGGAAACCUCUU
miR-495	2164	2170	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-504	3700	3706	m8	hsa-miR-504	AGACCCUGGUCUGCACUCUAU
miR-7	382	388	1A	hsa-miR-7^SZ	UGGAAGACUAGUGAUUUUGUUG
miR-93.hd/291-3p/294/295/302/372/373/520	2145	2152	1A,m8	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU
				hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU
miR-96	3992	3998	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.