Gene Page: RANBP1

Summary
GeneID  5902
Symbol  RANBP1
Synonyms  HTF9A|MGC88701
Description  RAN binding protein 1
See related  HGNC:9847|MIM:601180|Ensembl:ENSG00000099901|HPRD:03110|
Locus tag  -
Gene type  protein-coding
Map location  22q11.21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.031 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0044 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
C17orf800.920.93
ZC3H11A0.920.92
ZC3H7A0.920.92
MED230.910.94
TTC370.910.92
VPS540.910.92
NEK40.900.92
HEATR60.900.91
GTF2I0.900.92
ADAM170.900.93
Top 10 negatively co-expressed genes
MT-CO2-0.76-0.82
AF347015.31-0.76-0.82
AF347015.21-0.76-0.84
IFI27-0.74-0.78
AF347015.27-0.73-0.79
AF347015.8-0.71-0.79
HIGD1B-0.71-0.78
FXYD1-0.71-0.76
MT-CYB-0.70-0.76
AF347015.33-0.70-0.76
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005096GTPase activator activityIEA-
GO:0005092GDP-dissociation inhibitor activityTAS7616957 
GO:0005515protein bindingIPI17353931 
GO:0008536Ran GTPase bindingTAS7882974 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionTAS16130169 
GO:0007051spindle organizationIEA-
GO:0046907intracellular transportIEA-
GO:0046604positive regulation of mitotic centrosome separationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005813centrosomeIEA-
GO:0005634nucleusTAS16130169 
GO:0005737cytoplasmTAS16130169 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD93C1QR1 | C1qR(P) | C1qRP | CDw93 | MXRA4 | dJ737E23.1CD93 moleculeCD93 interacts with RanBP.BIND15459234 
KPNB1IMB1 | IPOB | Impnb | MGC2155 | MGC2156 | MGC2157 | NTF97karyopherin (importin) beta 1Reconstituted ComplexBioGRID10473610 |10779340 
MPGAAG | APNG | CRA36.1 | MDG | Mid1 | PIG11 | PIG16 | anpgN-methylpurine-DNA glycosylaseAffinity Capture-MSBioGRID17353931 
RANARA24 | Gsp1 | TC4RAN, member RAS oncogene family-HPRD,BioGRID7891706 |10779340 
RANGRFDKFZp686F02139 | HSPC165 | HSPC236 | MGC110973 | MOG1 | RANGNRFRAN guanine nucleotide release factor-HPRD10811801 
RCC1CHC1 | RCC1-Iregulator of chromosome condensation 1-HPRD7616957 
XPO1CRM1 | DKFZp686B1823exportin 1 (CRM1 homolog, yeast)Reconstituted ComplexBioGRID10601307 |10779340 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_RANMS_PATHWAY 107All SZGR genes in this pathway
PID_E2F_PATHWAY 7448All SZGR genes in this pathway
REACTOME_HIV_INFECTION 207122All SZGR genes in this pathway
REACTOME_HIV_LIFE_CYCLE 12569All SZGR genes in this pathway
REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 13281All SZGR genes in this pathway
REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 10461All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
VECCHI_GASTRIC_CANCER_EARLY_UP 430232All SZGR genes in this pathway
ODONNELL_TFRC_TARGETS_DN 13976All SZGR genes in this pathway
ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN 4525All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP 181101All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_DN 228137All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
MISSIAGLIA_REGULATED_BY_METHYLATION_DN 12267All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM 15993All SZGR genes in this pathway
TSAI_RESPONSE_TO_IONIZING_RADIATION 149101All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
CAFFAREL_RESPONSE_TO_THC_24HR_5_DN 5935All SZGR genes in this pathway
BENPORATH_PROLIFERATION 14780All SZGR genes in this pathway
STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN 517309All SZGR genes in this pathway
STARK_HYPPOCAMPUS_22Q11_DELETION_DN 2019All SZGR genes in this pathway
MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP 11069All SZGR genes in this pathway
MANALO_HYPOXIA_DN 289166All SZGR genes in this pathway
SCHUHMACHER_MYC_TARGETS_UP 8057All SZGR genes in this pathway
ZHAN_MULTIPLE_MYELOMA_SUBGROUPS 3020All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN 8757All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN 184132All SZGR genes in this pathway
LY_AGING_PREMATURE_DN 3017All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_DN 8759All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
ZHU_CMV_ALL_UP 12089All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
ZHU_CMV_24_HR_UP 9365All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G1 6741All SZGR genes in this pathway
LY_AGING_OLD_DN 5635All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA 5135All SZGR genes in this pathway
ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP 863514All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_DN 14593All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
KOBAYASHI_EGFR_SIGNALING_24HR_DN 251151All SZGR genes in this pathway
FOURNIER_ACINAR_DEVELOPMENT_LATE_2 277172All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
WINNEPENNINCKX_MELANOMA_METASTASIS_UP 16286All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 14386All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR 8549All SZGR genes in this pathway
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR 12873All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4957682m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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