Gene Page: BCAN

Summary
GeneID  63827
Symbol  BCAN
Synonyms  BEHAB|CSPG7|MGC13038
Description  brevican
See related  HGNC:23059|MIM:600347|Ensembl:ENSG00000132692|HPRD:02644|HPRD:09821|
Locus tag  RP11-66D17.1
Gene type  protein-coding
Map location  1q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
ExpressionExpressionP value: 2.26 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005529sugar bindingIEA-
GO:0005540hyaluronic acid bindingIEA-
GO:0005488bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005578proteinaceous extracellular matrixIEA-
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0005739mitochondrionIDA18029348 
GO:0016020membraneIEA-
GO:0031225anchored to membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
FBLN2-fibulin 2-HPRD,BioGRID11038354 
MMP1CLG | CLGNmatrix metallopeptidase 1 (interstitial collagenase)-HPRD,BioGRID10986281 
MMP10SL-2 | STMY2matrix metallopeptidase 10 (stromelysin 2)-HPRD,BioGRID10986281 
MMP13CLG3matrix metallopeptidase 13 (collagenase 3)-HPRD,BioGRID10986281 
MMP2CLG4 | CLG4A | MMP-II | MONA | TBE-1matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)-HPRD,BioGRID10986281 
MMP3MGC126102 | MGC126103 | MGC126104 | MMP-3 | SL-1 | STMY | STMY1 | STR1matrix metallopeptidase 3 (stromelysin 1, progelatinase)-HPRD,BioGRID10986281 
MMP7MMP-7 | MPSL1 | PUMP-1matrix metallopeptidase 7 (matrilysin, uterine)-HPRD,BioGRID10986281 
MMP8CLG1 | HNC | PMNL-CLmatrix metallopeptidase 8 (neutrophil collagenase)-HPRD,BioGRID10986281 
TNRMGC149328 | TN-Rtenascin R (restrictin, janusin)-HPRD9294172 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_CS_DS_DEGRADATION 129All SZGR genes in this pathway
REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS 2115All SZGR genes in this pathway
REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM 4933All SZGR genes in this pathway
REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM 5233All SZGR genes in this pathway
REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 11169All SZGR genes in this pathway
REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS 2517All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP 552347All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION 5026All SZGR genes in this pathway
LI_CISPLATIN_RESISTANCE_DN 3520All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_DN 15093All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LEIN_ASTROCYTE_MARKERS 4235All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
NABA_PROTEOGLYCANS 3523All SZGR genes in this pathway
NABA_CORE_MATRISOME 275148All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.14144201Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-132/212447453m8hsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-274314371Ahsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-4944504561Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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