Gene Page: SNCG

Summary
GeneID  6623
Symbol  SNCG
Synonyms  BCSG1|SR
Description  synuclein, gamma (breast cancer-specific protein 1)
See related  HGNC:11141|MIM:602998|Ensembl:ENSG00000173267|HPRD:04297|
Locus tag  -
Gene type  protein-coding
Map location  10q23.2-q23.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
EFHD10.940.91
PRR180.930.93
CNP0.930.91
HSPA20.910.89
FA2H0.900.91
CLDN110.900.83
ZCCHC240.890.91
ERBB30.890.94
MAG0.890.88
PADI20.890.91
Top 10 negatively co-expressed genes
POLB-0.61-0.74
TRNAU1AP-0.60-0.68
NR2C2AP-0.60-0.71
STMN1-0.59-0.67
ING4-0.59-0.66
DUSP12-0.58-0.66
MED19-0.58-0.67
HN1-0.58-0.65
ALKBH2-0.58-0.71
NKIRAS2-0.58-0.57
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17353931 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0043025cell somaIEAaxon, dendrite (GO term level: 4)-
GO:0030424axonIEAneuron, axon, Neurotransmitter (GO term level: 6)-
GO:0005813centrosomeIEA-
GO:0005819spindleIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BUB1BBUB1beta | BUBR1 | Bub1A | MAD3L | SSK1 | hBUBR1budding uninhibited by benzimidazoles 1 homolog beta (yeast)-HPRD,BioGRID14576821 
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1Affinity Capture-MSBioGRID17353931 
EXT2SOTVexostoses (multiple) 2Affinity Capture-MSBioGRID17353931 
FABP4A-FABP | aP2fatty acid binding protein 4, adipocyteAffinity Capture-MSBioGRID17353931 
FUBP1FBP | FUBPfar upstream element (FUSE) binding protein 1Affinity Capture-MSBioGRID17353931 
GRK1GPRK1 | RHOK | RKG protein-coupled receptor kinase 1Biochemical ActivityBioGRID10852916 
GRK5GPRK5G protein-coupled receptor kinase 5-HPRD,BioGRID10852916 
GRK6FLJ32135 | GPRK6G protein-coupled receptor kinase 6Biochemical ActivityBioGRID10852916 
HNF4AFLJ39654 | HNF4 | HNF4a7 | HNF4a8 | HNF4a9 | MODY | MODY1 | NR2A1 | NR2A21 | TCF | TCF14hepatocyte nuclear factor 4, alphaAffinity Capture-MSBioGRID17353931 
MAPK1ERK | ERK2 | ERT1 | MAPK2 | P42MAPK | PRKM1 | PRKM2 | p38 | p40 | p41 | p41mapkmitogen-activated protein kinase 1Affinity Capture-WesternBioGRID12121974 
MAPK3ERK1 | HS44KDAP | HUMKER1A | MGC20180 | P44ERK1 | P44MAPK | PRKM3mitogen-activated protein kinase 3Affinity Capture-WesternBioGRID12121974 
MAPK8JNK | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1mitogen-activated protein kinase 8-HPRD,BioGRID12121974 
MCM3HCC5 | MGC1157 | P1-MCM3 | P1.h | RLFBminichromosome maintenance complex component 3Affinity Capture-MSBioGRID17353931 
TIMP2CSC-21KTIMP metallopeptidase inhibitor 2Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
LINDGREN_BLADDER_CANCER_CLUSTER_2A_UP 85All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
GOUYER_TATI_TARGETS_DN 1712All SZGR genes in this pathway
LE_EGR2_TARGETS_DN 10884All SZGR genes in this pathway
FRASOR_RESPONSE_TO_ESTRADIOL_DN 8252All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_UP 1813All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN 159105All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_NEURAL 12985All SZGR genes in this pathway
LU_EZH2_TARGETS_UP 295155All SZGR genes in this pathway
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN 11674All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_UP 169105All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_36HR 15288All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN 10677All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway


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