Gene Page: SNTA1

Summary
GeneID  6640
Symbol  SNTA1
Synonyms  SNT1|TACIP1|dJ1187J4.5
Description  syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
See related  HGNC:11167|MIM:601017|Ensembl:ENSG00000101400|HPRD:03009|
Locus tag  -
Gene type  protein-coding
Map location  20q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0279 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIEA-
GO:0005509calcium ion bindingIEA-
GO:0005516calmodulin bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007528neuromuscular junction developmentIEASynap (GO term level: 10)-
GO:0006936muscle contractionTAS8576247 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0005856cytoskeletonIEA-
GO:0005737cytoplasmIEA-
GO:0042383sarcolemmaIEA-
GO:0030054cell junctionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALM1CALML2 | CAMI | DD132 | PHKDcalmodulin 1 (phosphorylase kinase, delta)-HPRD9512352 
DGKZDAGK5 | DAGK6 | DGK-ZETA | hDGKzetadiacylglycerol kinase, zeta 104kDa-HPRD,BioGRID11352924 
DMDBMD | CMD3B | DXS142 | DXS164 | DXS206 | DXS230 | DXS239 | DXS268 | DXS269 | DXS270 | DXS272dystrophin-HPRD,BioGRID7890602 
DTNAD18S892E | DRP3 | DTN | FLJ96209 | LVNC1dystrobrevin, alpha-HPRD12206805 
-HPRD11069112 |12206805|12206805 
DTNBMGC17163 | MGC57126dystrobrevin, betaAffinity Capture-WesternBioGRID10545507 
GLSAAD20 | DKFZp686O15119 | FLJ10358 | GLS1 | KIAA0838glutaminase-HPRD,BioGRID11163757 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2-HPRD,BioGRID11278583 |11551227 
KCNJ12FLJ14167 | IRK2 | KCNJN1 | Kir2.2 | Kir2.2v | hIRK | hIRK1 | hkir2.2x | kcnj12xpotassium inwardly-rectifying channel, subfamily J, member 12-HPRD,BioGRID15024025 
KCNJ4HIR | HIRK2 | HRK1 | IRK3 | Kir2.3 | MGC142066 | MGC142068potassium inwardly-rectifying channel, subfamily J, member 4Affinity Capture-WesternBioGRID15024025 
MAPK12ERK3 | ERK6 | P38GAMMA | PRKM12 | SAPK-3 | SAPK3mitogen-activated protein kinase 12Affinity Capture-Western
Biochemical Activity
Two-hybrid		BioGRID10212242 
NOS1IHPS1 | NOS | nNOSnitric oxide synthase 1 (neuronal)-HPRD11747091 
Reconstituted ComplexBioGRID9412493 
SCN1AFEB3 | GEFSP2 | HBSCI | NAC1 | Nav1.1 | SCN1 | SMEIsodium channel, voltage-gated, type I, alpha subunitAffinity Capture-Western
Protein-peptide		BioGRID9412493 
SCN5ACDCD2 | CMD1E | CMPD2 | HB1 | HB2 | HBBD | HH1 | ICCD | IVF | LQT3 | Nav1.5 | PFHB1 | SSS1sodium channel, voltage-gated, type V, alpha subunitAffinity Capture-Western
Protein-peptide		BioGRID9412493 
UTRNDMDL | DRP | DRP1 | FLJ23678utrophin-HPRD,BioGRID8576247 
XRCC6CTC75 | CTCBF | G22P1 | KU70 | ML8 | TLAAX-ray repair complementing defective repair in Chinese hamster cells 6Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_P38_GAMMA_DELTA_PATHWAY 119All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_UP 184125All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_3_UP 329196All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP 185119All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_DN 4529All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
YAGI_AML_FAB_MARKERS 191131All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP 9258All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_UP 8458All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_UP 9564All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
HELLER_HDAC_TARGETS_UP 317208All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_CLASSICAL 162122All SZGR genes in this pathway
GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB 14583All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_UP 217131All SZGR genes in this pathway
WIERENGA_STAT5A_TARGETS_GROUP1 13676All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124/506234240m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-135268274m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-185488494m8hsa-miR-185brainUGGAGAGAAAGGCAGUUC
miR-34b6773m8hsa-miR-34bUAGGCAGUGUCAUUAGCUGAUUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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