Gene Page: SRI

Summary
GeneID  6717
Symbol  SRI
Synonyms  FLJ26259|SCN
Description  sorcin
See related  HGNC:11292|MIM:182520|Ensembl:ENSG00000075142|HPRD:01680|
Locus tag  -
Gene type  protein-coding
Map location  7q21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005102receptor bindingTASNeurotransmitter (GO term level: 4)9668070 
GO:0005509calcium ion bindingIEA-
GO:0005246calcium channel regulator activityTAS9668070 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001508regulation of action potentialTAS9668070 
GO:0007165signal transductionTAS16130169 
GO:0007517muscle developmentTAS9668070 
GO:0007507heart developmentTAS9668070 
GO:0008016regulation of heart contractionTAS9668070 
GO:0006810transportTAS9668070 
GO:0006942regulation of striated muscle contractionTAS9668070 
GO:0006880intracellular sequestering of iron ionTAS9668070 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmTAS16130169 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ALG2CDGIi | FLJ14511 | hALPG2asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)Reconstituted ComplexBioGRID12804766 
ANXA11ANX11 | CAP50annexin A11-HPRD9268363 
ANXA7ANX7 | SNX | SYNEXINannexin A7-HPRD,BioGRID9268363 
CACNA1CCACH2 | CACN2 | CACNL1A1 | CCHL1A1 | CaV1.2 | MGC120730 | TScalcium channel, voltage-dependent, L type, alpha 1C subunit-HPRD,BioGRID9668070 
CACNA1SCACNL1A3 | CCHL1A3 | Cav1.1 | HOKPP | MHS5 | hypoPPcalcium channel, voltage-dependent, L type, alpha 1S subunit-HPRD,BioGRID9668070 
CALCOCO2MGC17318 | NDP52calcium binding and coiled-coil domain 2Two-hybridBioGRID16189514 
GCAGCLgrancalcin, EF-hand calcium binding proteinSorcin interacts with grancalcin to form a heterodimer.BIND12804766 
-HPRD,BioGRID12804766 
PSEN2AD3L | AD4 | PS2 | STM2presenilin 2 (Alzheimer disease 4)-HPRD,BioGRID10748169 
RYR2ARVC2 | ARVD2 | VTSIPryanodine receptor 2 (cardiac)-HPRD,BioGRID7592856 
SRIFLJ26259 | SCNsorcin-HPRD,BioGRID11714909 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN 455304All SZGR genes in this pathway
NEWMAN_ERCC6_TARGETS_UP 2618All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_UP 14984All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN 14295All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN 153100All SZGR genes in this pathway
WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP 12172All SZGR genes in this pathway
OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 6940All SZGR genes in this pathway
GRUETZMANN_PANCREATIC_CANCER_UP 358245All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN 4328All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
TAKAO_RESPONSE_TO_UVB_RADIATION_UP 8655All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_MATURE_CELL 293160All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
KANG_FLUOROURACIL_RESISTANCE_UP 2215All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_DN 7657All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_DN 178121All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_UP 12375All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 473224All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 307185All SZGR genes in this pathway
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP 196137All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_DN 258160All SZGR genes in this pathway
MASSARWEH_RESPONSE_TO_ESTRADIOL 6147All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP 295149All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_DN 3019All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP 188121All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S1 237159All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
CHICAS_RB1_TARGETS_CONFLUENT 567365All SZGR genes in this pathway
GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB 14583All SZGR genes in this pathway
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN 505328All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
KRIEG_KDM3A_TARGETS_NOT_HYPOXIA 208107All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-5p131137m8hsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-542-3p534540m8hsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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