Gene Page: SSTR2

Summary
GeneID  6752
Symbol  SSTR2
Synonyms  -
Description  somatostatin receptor 2
See related  HGNC:11331|MIM:182452|Ensembl:ENSG00000180616|HPRD:01674|
Locus tag  -
Gene type  protein-coding
Map location  17q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MYO5A0.940.96
HECW20.930.94
LONRF20.930.95
SYT160.930.93
PCLO0.920.94
FAM126B0.910.94
UBR30.910.93
LMTK20.900.90
DGKE0.900.89
PLEKHM30.900.93
Top 10 negatively co-expressed genes
RAB34-0.55-0.69
EFEMP2-0.53-0.58
DBI-0.52-0.67
RHOC-0.51-0.65
C19orf36-0.49-0.58
ACSF2-0.49-0.62
GATSL3-0.48-0.57
TLCD1-0.48-0.58
C1orf61-0.48-0.73
ACP6-0.47-0.51
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004994somatostatin receptor activityTAS7914078 
GO:0005515protein bindingIPI10551867 
GO:0030165PDZ domain bindingIPI10551867 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007218neuropeptide signaling pathwayIEANeurotransmitter (GO term level: 8)-
GO:0007187G-protein signaling, coupled to cyclic nucleotide second messengerTAS7914078 
GO:0007267cell-cell signalingTAS1346068 
GO:0007193G-protein signaling, adenylate cyclase inhibiting pathwayIEA-
GO:0007165signal transductionIEA-
GO:0008285negative regulation of cell proliferationTAS9892014 
GO:0007586digestionTAS1346068 
GO:0007584response to nutrientTAS1346068 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionIEA-
GO:0005737cytoplasmIDA18029348 
GO:0005886plasma membraneTAS7914078 
GO:0005887integral to plasma membraneTAS7914078 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CORTCST-14 | CST-17 | CST-29cortistatin-HPRD,BioGRID9125122 
GNAI1Giguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1-HPRD,BioGRID7914078 
PTPN6HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1protein tyrosine phosphatase, non-receptor type 6-HPRD,BioGRID9305905 |11920268 
SHANK1SPANK-1 | SSTRIP | synamonSH3 and multiple ankyrin repeat domains 1-HPRD,BioGRID10551867 
SHANK2CORTBP1 | CTTNBP1 | ProSAP1 | SHANK | SPANK-3SH3 and multiple ankyrin repeat domains 2-HPRD10373412 
SSTSMSTsomatostatin-HPRD1346068 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS 195114All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP 431237All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 229137All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
LEE_TARGETS_OF_PTCH1_AND_SUFU_UP 5337All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON 335181All SZGR genes in this pathway
SASAKI_ADULT_T_CELL_LEUKEMIA 176122All SZGR genes in this pathway
PENG_RAPAMYCIN_RESPONSE_UP 203130All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
NOUZOVA_METHYLATED_IN_APL 6839All SZGR genes in this pathway
MCCLUNG_CREB1_TARGETS_UP 10072All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_UP 8152All SZGR genes in this pathway
HELLER_SILENCED_BY_METHYLATION_UP 282183All SZGR genes in this pathway
OSADA_ASCL1_TARGETS_UP 4630All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED 8050All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED 6331All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED 228119All SZGR genes in this pathway
HOELZEL_NF1_TARGETS_DN 11573All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
LOPEZ_TRANSLATION_VIA_FN1_SIGNALING 3521All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway
BOSCO_TH1_CYTOTOXIC_MODULE 11462All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.