Gene Page: TF

Summary
GeneID  7018
Symbol  TF
Synonyms  DKFZp781D0156|PRO1557|PRO2086
Description  transferrin
See related  HGNC:11740|MIM:190000|Ensembl:ENSG00000091513|HPRD:01811|
Locus tag  -
Gene type  protein-coding
Map location  3q22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenics, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0982 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HADHB0.840.85
CYP2J20.840.85
HSPB80.820.86
CSRP10.810.83
SDC40.810.82
TMBIM10.800.86
CKMT20.800.75
EFEMP10.800.78
STOM0.790.82
GRAMD30.790.84
Top 10 negatively co-expressed genes
NKIRAS2-0.58-0.55
CRMP1-0.57-0.57
GPRIN1-0.57-0.58
ZNF821-0.56-0.56
C19orf57-0.56-0.57
NR2C2AP-0.56-0.62
MPP3-0.56-0.58
AC011491.1-0.56-0.65
GMIP-0.56-0.57
HN1-0.55-0.59
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008199ferric iron bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006826iron ion transportIEA-
GO:0006811ion transportIEA-
GO:0006879cellular iron ion homeostasisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005576extracellular regionNAS14718574 
GO:0005739mitochondrionIDA18029348 
GO:0005768endosomeIEA-
GO:0030139endocytic vesicleIDA15229288 |15292400 
GO:0030139endocytic vesicleIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALRCRT | FLJ26680 | RO | SSA | cC1qRcalreticulin-HPRD,BioGRID9312001 
CANXCNX | FLJ26570 | IP90 | P90calnexin-HPRD,BioGRID9312001 
CUBNFLJ90055 | FLJ90747 | IFCR | MGA1 | gp280cubilin (intrinsic factor-cobalamin receptor)Transferrin interacts with Cubilin.BIND11606717 
FNBP1FBP17 | KIAA0554 | MGC126804formin binding protein 1Co-localizationBioGRID15252009 
IGF1IGFIinsulin-like growth factor 1 (somatomedin C)Reconstituted ComplexBioGRID11749962 
IGF2C11orf43 | FLJ22066 | FLJ44734 | INSIGF | pp9974insulin-like growth factor 2 (somatomedin A)Reconstituted ComplexBioGRID11749962 
IGFBP1AFBP | IBP1 | IGF-BP25 | PP12 | hIGFBP-1insulin-like growth factor binding protein 1-HPRD11297622 
IGFBP2IBP2 | IGF-BP53insulin-like growth factor binding protein 2, 36kDa-HPRD11297622 
IGFBP3BP-53 | IBP3insulin-like growth factor binding protein 3-HPRD,BioGRID11297622 |11749962 
IGFBP4BP-4 | HT29-IGFBP | IBP4 | IGFBP-4insulin-like growth factor binding protein 4-HPRD11297622 
IGFBP5IBP5insulin-like growth factor binding protein 5-HPRD11297622 
IGFBP6IBP6insulin-like growth factor binding protein 6-HPRD11297622 
TFR2HFE3 | MGC126368 | TFRC2transferrin receptor 2-HPRD,BioGRID11027676 
TFRCCD71 | TFR | TFR1 | TRFRtransferrin receptor (p90, CD71)Tf interacts with TfR.BIND15525538 
Reconstituted ComplexBioGRID11027676 
-HPRD6268632 
TUBB3MC1R | TUBB4 | beta-4tubulin, beta 3Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ST_WNT_CA2_CYCLIC_GMP_PATHWAY 2014All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY 4038All SZGR genes in this pathway
PID_HIF1_TFPATHWAY 6652All SZGR genes in this pathway
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ 8956All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_IRON_UPTAKE_AND_TRANSPORT 3618All SZGR genes in this pathway
REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING 2510All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION 208138All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN 198110All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
MANTOVANI_VIRAL_GPCR_SIGNALING_DN 4937All SZGR genes in this pathway
BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN 4634All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_D 3714All SZGR genes in this pathway
COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP 3532All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_DN 357212All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_2 11476All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
MATSUDA_NATURAL_KILLER_DIFFERENTIATION 475313All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_DN 12986All SZGR genes in this pathway
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN 7748All SZGR genes in this pathway
HARRIS_HYPOXIA 8164All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
SEMENZA_HIF1_TARGETS 3632All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_UP 202115All SZGR genes in this pathway
CHENG_RESPONSE_TO_NICKEL_ACETATE 4529All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM 6647All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST 13293All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
CADWELL_ATG16L1_TARGETS_UP 9356All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN 5734All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
POOLA_INVASIVE_BREAST_CANCER_DN 13483All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G3_DN 5132All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP 307182All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_UP 387225All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP 504321All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP 8950All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway


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