|
|
| GeneID |
7080
|
| Symbol |
NKX2-1
|
| Synonyms |
BCH|BHC|NK-2|NKX2.1|NKX2A|TEBP|TITF1|TTF-1|TTF1
|
| Description |
NK2 homeobox 1 |
| See related |
HGNC:11825|MIM:600635|Ensembl:ENSG00000136352|HPRD:02798| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
14q13 |
|
| |
|
|
| Gene set name |
Method of gene set |
Evidence |
Info |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 3 | |
|
| |
| General Gene Expression (microarray) ? |
|
 |
| |
| Gene Expression in Brain Regions (new) |
|
| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| FAM176B | 0.77 | 0.66 | | |
| VAMP5 | 0.70 | 0.56 | | |
| IFI27 | 0.70 | 0.50 | | |
| METRN | 0.70 | 0.49 | | |
| IL32 | 0.69 | 0.64 | | |
| GSDMD | 0.68 | 0.56 | | |
| CLDN5 | 0.68 | 0.68 | | |
| GNG11 | 0.67 | 0.54 | | |
| CRIP1 | 0.67 | 0.51 | | |
| IGFBP7 | 0.64 | 0.63 | | |
Top 10 negatively co-expressed genes | | WAC | -0.61 | -0.61 | | |
| EZH1 | -0.60 | -0.60 | | |
| SLC4A1AP | -0.58 | -0.51 | | |
| ZNF331 | -0.58 | -0.59 | | |
| MTMR15 | -0.58 | -0.56 | | |
| PTK2 | -0.57 | -0.53 | | |
| HBS1L | -0.57 | -0.58 | | |
| PIAS2 | -0.56 | -0.54 | | |
| DDHD1 | -0.56 | -0.52 | | |
| FBXW11 | -0.56 | -0.50 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0003700 | transcription factor activity | IEA | | - |
| GO:0005515 | protein binding | ISS | | - |
| GO:0016563 | transcription activator activity | ISS | | - |
| GO:0016563 | transcription activator activity | NAS | | 7711080 |7713914 |
| GO:0043565 | sequence-specific DNA binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007420 | brain development | IEA | Brain (GO term level: 7) | - |
| GO:0001764 | neuron migration | IEA | neuron (GO term level: 8) | - |
| GO:0021798 | forebrain dorsal/ventral pattern formation | IEA | Brain (GO term level: 10) | - |
| GO:0009887 | organ morphogenesis | IEA | | - |
| GO:0007492 | endoderm development | IEA | | - |
| GO:0007389 | pattern specification process | IEA | | - |
| GO:0030878 | thyroid gland development | IEA | | - |
| GO:0030324 | lung development | IEA | | - |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005634 | nucleus | NAS | | - |
| GO:0005654 | nucleoplasm | ISS | | - |
| GO:0005667 | transcription factor complex | IEA | | - |
| |
|
|
| |
|
|
|
|
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
|
