Gene Page: TNNI3

Summary
GeneID  7137
Symbol  TNNI3
Synonyms  CMD2A|CMH7|MGC116817|TNNC1|cTnI
Description  troponin I type 3 (cardiac)
See related  HGNC:11947|MIM:191044|Ensembl:ENSG00000129991|HPRD:11769|
Locus tag  -
Gene type  protein-coding
Map location  19q13.4
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIDA10806205 
GO:0048306calcium-dependent protein bindingIPI7957210 
GO:0019855calcium channel inhibitor activityIPI12809519 
GO:0030172troponin C bindingIPI7957210 |11735257 |15542288 
GO:0019904protein domain specific bindingIPI11984006 
GO:0031014troponin T bindingIPI15542288 
GO:0019901protein kinase bindingIPI12721663 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001980regulation of systemic arterial blood pressure by ischemic conditionsISSBrain (GO term level: 9)-
GO:0001570vasculogenesisISS-
GO:0055010ventricular cardiac muscle morphogenesisIMP11815426 
GO:0007507heart developmentISS-
GO:0006937regulation of muscle contractionIEA-
GO:0006874cellular calcium ion homeostasisISS-
GO:0032780negative regulation of ATPase activityIDA7957210 |11735257 
GO:0032780negative regulation of ATPase activityIMP10806205 
GO:0060048cardiac muscle contractionIMP11735257 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005861troponin complexIDA7957210 |10806205 |10850966 
|12093807 
GO:0030017sarcomereIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTA1ACTA | ASMA | CFTD | CFTD1 | CFTDM | MPFD | NEM1 | NEM2 | NEM3actin, alpha 1, skeletal muscle-HPRD12383268 
LYSTCHS | CHS1lysosomal trafficking regulatorTwo-hybridBioGRID11984006 
PAPPAASBABP2 | DIPLA1 | IGFBP-4ase | PAPA | PAPP-A | PAPPA1pregnancy-associated plasma protein A, pappalysin 1-HPRD12626203 
PKD2APKD2 | MGC138466 | MGC138468 | PC2 | PKD4polycystic kidney disease 2 (autosomal dominant)-HPRD,BioGRID12525172 
PKD2L1PCL | PKD2L | PKDLpolycystic kidney disease 2-like 1-HPRD,BioGRID12809519 
TNNC1CMD1Z | TNC | TNNCtroponin C type 1 (slow)-HPRD,BioGRID9346285 |11904166 
|12060657 |12122471 
|12939162 |15049709 
|15134451 
TNNI3KCARK | MGC142099 | MGC33828TNNI3 interacting kinase-HPRD,BioGRID12721663 
TNNT1ANM | FLJ98147 | MGC104241 | STNT | TNT | TNTStroponin T type 1 (skeletal, slow)-HPRD11904166 
TNNT2CMH2 | CMPD2 | MGC3889 | TnTC | cTnTtroponin T type 2 (cardiac)Reconstituted ComplexBioGRID11904166 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CARDIAC_MUSCLE_CONTRACTION 8051All SZGR genes in this pathway
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 8565All SZGR genes in this pathway
KEGG_DILATED_CARDIOMYOPATHY 9268All SZGR genes in this pathway
REACTOME_STRIATED_MUSCLE_CONTRACTION 2712All SZGR genes in this pathway
REACTOME_MUSCLE_CONTRACTION 4824All SZGR genes in this pathway
PIEPOLI_LGI1_TARGETS_DN 146All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_3 4831All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
AFFAR_YY1_TARGETS_DN 234137All SZGR genes in this pathway
ZHU_CMV_24_HR_DN 9164All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
ZHU_CMV_ALL_DN 12893All SZGR genes in this pathway
ZAMORA_NOS2_TARGETS_DN 9671All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_UP 172109All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP 165118All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED 8050All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.