Gene Page: C4BPA

Summary
GeneID  722
Symbol  C4BPA
Synonyms  C4BP|PRP
Description  complement component 4 binding protein, alpha
See related  HGNC:1325|MIM:120830|Ensembl:ENSG00000123838|HPRD:00403|
Locus tag  RP11-164O23.4
Gene type  protein-coding
Map location  1q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 2.166 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
KIF3C0.940.94
NEURL40.930.94
CLIP20.930.93
BAHD10.920.93
MGRN10.920.95
SREBF20.920.95
RUSC20.920.94
MKL10.920.94
HIRA0.920.94
SIN3B0.920.93
Top 10 negatively co-expressed genes
AF347015.31-0.77-0.83
MT-CO2-0.76-0.84
AF347015.33-0.75-0.80
S100B-0.74-0.81
AF347015.27-0.74-0.82
FXYD1-0.74-0.80
MT-CYB-0.73-0.80
AC021016.1-0.73-0.83
AF347015.8-0.72-0.82
COPZ2-0.71-0.76
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16330538 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006958complement activation, classical pathwayIEA-
GO:0045087innate immune responseIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionNAS14718574 
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APCSMGC88159 | PTX2 | SAPamyloid P component, serum-HPRD,BioGRID7592941 
C4BC4A | C4A13 | C4A91 | C4B1 | C4B12 | C4B2 | C4B3 | C4B5 | C4F | CH | CO4 | CPAMD3 | FLJ60561 | MGC164979complement component 4B (Childo blood group)-HPRD,BioGRID10383431 
LRP1A2MR | APOER | APR | CD91 | FLJ16451 | IGFBP3R | LRP | MGC88725 | TGFBR5low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)-HPRD11705989 
PROS1PROS | PS21 | PS22 | PS23 | PS24 | PS25 | PSAprotein S (alpha)-HPRD,BioGRID1534488 |1833851 
|10744423 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 6949All SZGR genes in this pathway
PID_CD40_PATHWAY 3126All SZGR genes in this pathway
REACTOME_REGULATION_OF_COMPLEMENT_CASCADE 1412All SZGR genes in this pathway
REACTOME_INNATE_IMMUNE_SYSTEM 279178All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_COMPLEMENT_CASCADE 3222All SZGR genes in this pathway
LEE_LIVER_CANCER_CIPROFIBRATE_DN 6643All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_TGFA_DN 6544All SZGR genes in this pathway
LEE_LIVER_CANCER_ACOX1_DN 6539All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_E2F1_DN 6438All SZGR genes in this pathway
LEE_LIVER_CANCER_DENA_DN 7445All SZGR genes in this pathway
LEE_LIVER_CANCER_MYC_DN 6340All SZGR genes in this pathway
LEE_LIVER_CANCER_E2F1_DN 6442All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES 244154All SZGR genes in this pathway
KAYO_AGING_MUSCLE_UP 244165All SZGR genes in this pathway
GAJATE_RESPONSE_TO_TRABECTEDIN_UP 6745All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_UP 7148All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2 7142All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_WITH_H3K27ME3 19693All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_DN 8054All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S3 266180All SZGR genes in this pathway
OHGUCHI_LIVER_HNF4A_TARGETS_DN 14985All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway


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