Gene Page: VASP

Summary
GeneID  7408
Symbol  VASP
Synonyms  -
Description  vasodilator-stimulated phosphoprotein
See related  HGNC:12652|MIM:601703|Ensembl:ENSG00000125753|HPRD:03415|
Locus tag  -
Gene type  protein-coding
Map location  19q13.2-q13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIEA-
GO:0005515protein bindingIEA-
GO:0017124SH3 domain bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007411axon guidanceIEAaxon (GO term level: 13)-
GO:0001843neural tube closureIEA-
GO:0030036actin cytoskeleton organizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030175filopodiumIEAaxon (GO term level: 5)-
GO:0005737cytoplasmIEA-
GO:0030027lamellipodiumIEA-
GO:0005925focal adhesionIEA-
GO:0005886plasma membraneIEA-
GO:0015629actin cytoskeletonTAS7828592 
GO:0030054cell junctionIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APBB1IPINAG1 | PREL1 | RARP1 | RIAMamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein-HPRD15469846 |15642358 
RIAM interacts with VASP.BIND15469846 
DMRTB1-DMRT-like family B with proline-rich C-terminal, 1Two-hybridBioGRID16189514 
DNMBPKIAA1010 | TUBAdynamin binding proteinReconstituted ComplexBioGRID14506234 
ERMAPMGC118810 | MGC118811 | MGC118812 | MGC118813 | PRO2801 | RD | SCerythroblast membrane-associated protein (Scianna blood group)-HPRD15469845 
FYBADAP | PRO0823 | SLAP-130FYN binding protein (FYB-120/130)-HPRD,BioGRID10747096 
GSNDKFZp313L0718gelsolin (amyloidosis, Finnish type)-HPRD11093254 
LPP-LIM domain containing preferred translocation partner in lipoma-HPRD10637295 
NOL3ARC | CARD2 | MYC | MYP | NOP | NOP30nucleolar protein 3 (apoptosis repressor with CARD domain)Two-hybridBioGRID16189514 
PFN1-profilin 1-HPRD,BioGRID10882740 
PFN2D3S1319E | PFLprofilin 2-HPRD,BioGRID7737110 |10882740 
PLSCR1MMTRA1Bphospholipid scramblase 1Two-hybridBioGRID16189514 
RAPH1ALS2CR18 | ALS2CR9 | KIAA1681 | LPD | PREL2 | RMO1 | RalGDS/AF-6Ras association (RalGDS/AF-6) and pleckstrin homology domains 1Reconstituted ComplexBioGRID15469845 
TESDKFZp586B2022 | MGC1146 | TESS | TESS-2testis derived transcript (3 LIM domains)Affinity Capture-Western
Reconstituted Complex		BioGRID12695497 
TES interacts with VASP.BIND12571287 
TRIM9KIAA0282 | RNF91 | SPRINGtripartite motif-containing 9Two-hybridBioGRID16189514 
VASP-vasodilator-stimulated phosphoprotein-HPRD,BioGRID12220179 
VCLCMD1W | MVCLvinculin-HPRD,BioGRID10882740 
WASIMD2 | THC | WASPWiskott-Aldrich syndrome (eczema-thrombocytopenia)-HPRD,BioGRID11598004 
WWP2AIP2 | WWp2-likeWW domain containing E3 ubiquitin protein ligase 2Two-hybridBioGRID16189514 
XPO6EXP6 | FLJ22519 | KIAA0370 | RANBP20exportin 6-HPRD,BioGRID14592989 
ZYXESP-2 | HED-2zyxin-HPRD7644520 |10801818 
|10851246 |10882740 
Affinity Capture-Western
in vitro
in vivo
Two-hybrid		BioGRID10801818 |10882740 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_FOCAL_ADHESION 201138All SZGR genes in this pathway
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 9771All SZGR genes in this pathway
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 11878All SZGR genes in this pathway
SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES 3525All SZGR genes in this pathway
ST_INTEGRIN_SIGNALING_PATHWAY 8262All SZGR genes in this pathway
PID_ECADHERIN_KERATINOCYTE_PATHWAY 2119All SZGR genes in this pathway
PID_IL8_CXCR2_PATHWAY 3426All SZGR genes in this pathway
PID_ECADHERIN_STABILIZATION_PATHWAY 4234All SZGR genes in this pathway
PID_THROMBIN_PAR1_PATHWAY 4332All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_CELL_CELL_COMMUNICATION 12077All SZGR genes in this pathway
REACTOME_TCR_SIGNALING 5446All SZGR genes in this pathway
REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES 2725All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_SIGNALING_BY_ROBO_RECEPTOR 3026All SZGR genes in this pathway
REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS 1410All SZGR genes in this pathway
REACTOME_CELL_JUNCTION_ORGANIZATION 7843All SZGR genes in this pathway
REACTOME_IMMUNE_SYSTEM 933616All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM 539350All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
RODRIGUES_NTN1_TARGETS_DN 158102All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_DN 214133All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 229137All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP 479299All SZGR genes in this pathway
RICKMAN_METASTASIS_DN 261155All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
AMIT_EGF_RESPONSE_480_HELA 164118All SZGR genes in this pathway
CHANG_POU5F1_TARGETS_UP 1510All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
MA_MYELOID_DIFFERENTIATION_UP 3929All SZGR genes in this pathway
YAGI_AML_SURVIVAL 12987All SZGR genes in this pathway
KYNG_DNA_DAMAGE_BY_UV 6243All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
MUELLER_PLURINET 299189All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
MARTENS_BOUND_BY_PML_RARA_FUSION 456287All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-17-5p/20/93.mr/106/519.d3353411Ahsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-204/2114124191A,m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-2141801861Ahsa-miR-214brainACAGCAGGCACAGACAGGCAG
miR-224995061A,m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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