Gene Page: VIP

Summary
GeneID  7432
Symbol  VIP
Synonyms  MGC13587|PHM27
Description  vasoactive intestinal peptide
See related  HGNC:12693|MIM:192320|Ensembl:ENSG00000146469|HPRD:15950|
Locus tag  -
Gene type  protein-coding
Map location  6q25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ADORA2A0.94-0.23
AC005512.10.930.69
RASD20.920.56
TMEM90A0.900.29
ADRA2C0.900.49
RGS90.90-0.20
RGS140.880.64
PENK0.880.02
PTPN70.880.23
LINGO30.870.68
Top 10 negatively co-expressed genes
BLVRA-0.23-0.42
STMN1-0.23-0.57
PGBD1-0.22-0.60
FAM40A-0.21-0.52
CABYR-0.21-0.49
ZNF311-0.21-0.63
ASGR1-0.21-0.53
TUBB2B-0.20-0.64
TUBB-0.20-0.56
FXYD6-0.20-0.44
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005184neuropeptide hormone activityTASaxon, Synap, Brain, Neurotransmitter (GO term level: 6)10096039 
GO:0005179hormone activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayTAS10096039 
GO:0008284positive regulation of cell proliferationTAS8389448 
GO:0007589body fluid secretionTAS4035357 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MEOX2GAX | MOX2mesenchyme homeobox 2Two-hybridBioGRID16189514 
MEP1APPHAmeprin A, alpha (PABA peptide hydrolase)Biochemical ActivityBioGRID11278902 
VIPR1FLJ41949 | HVR1 | II | PACAP-R-2 | RDC1 | VAPC1 | VIPR | VIRG | VPAC1 | VPCAP1Rvasoactive intestinal peptide receptor 1-HPRD8074647 |11027527 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BIOCARTA_VIP_PATHWAY 2926All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS 8858All SZGR genes in this pathway
REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS 3322All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS 12182All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN 291176All SZGR genes in this pathway
SCHRAMM_INHBA_TARGETS_UP 77All SZGR genes in this pathway
WOTTON_RUNX_TARGETS_DN 2918All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP 176115All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_NEURAL 12985All SZGR genes in this pathway
SERVITJA_ISLET_HNF1A_TARGETS_UP 163111All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_DN 418245All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1281821881Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-271821891A,m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-30-5p1901961Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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