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GeneID |
796
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Symbol |
CALCA
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Synonyms |
CALC1|CGRP|CGRP-I|CGRP1|CT|KC|MGC126648
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Description |
calcitonin-related polypeptide alpha |
See related |
HGNC:1437|MIM:114130|Ensembl:ENSG00000110680|HPRD:00238| |
Locus tag |
- |
Gene type |
protein-coding |
Map location |
11p15.2-p15.1 |
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Gene set name |
Method of gene set |
Evidence |
Info |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 4 | |
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General Gene Expression (microarray) ? |
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Gene Expression in Brain Regions (new) |
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Top co-expressed genes in Brain Regions (new) |
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Gene | Pearson's Correlation | Spearman's Correlation | | |
Top 10 positively co-expressed genes |
GOLIM4 | 0.81 | 0.83 | | |
COBLL1 | 0.78 | 0.79 | | |
TLN1 | 0.75 | 0.81 | | |
PTRF | 0.73 | 0.76 | | |
CGNL1 | 0.72 | 0.78 | | |
FYCO1 | 0.72 | 0.82 | | |
COL14A1 | 0.71 | 0.73 | | |
GIMAP8 | 0.71 | 0.74 | | |
MYH11 | 0.71 | 0.71 | | |
FAM129A | 0.70 | 0.73 | | |
Top 10 negatively co-expressed genes | ZNF32 | -0.49 | -0.59 | | |
COMMD3 | -0.47 | -0.56 | | |
NDUFAF2 | -0.47 | -0.55 | | |
PFDN5 | -0.47 | -0.59 | | |
PHPT1 | -0.46 | -0.57 | | |
OXSM | -0.46 | -0.54 | | |
C11orf73 | -0.46 | -0.54 | | |
MRPS24 | -0.46 | -0.50 | | |
AC034193.4 | -0.46 | -0.50 | | |
DCTN3 | -0.46 | -0.49 | | |
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Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0005179 | hormone activity | IEA | | - |
GO:0031716 | calcitonin receptor binding | IEA | | - |
GO:0031716 | calcitonin receptor binding | IPI | | 8078488 |8940110 |
Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0007218 | neuropeptide signaling pathway | IEA | Neurotransmitter (GO term level: 8) | - |
GO:0001984 | vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure | IEA | | - |
GO:0002027 | regulation of heart rate | IEA | | - |
GO:0001944 | vasculature development | IDA | | 17267696 |
GO:0001935 | endothelial cell proliferation | IDA | | 17267696 |
GO:0001976 | regulation of systemic arterial blood pressure by neurological process | IDA | | 10642343 |
GO:0007190 | activation of adenylate cyclase activity | IDA | | 10822112 |16014619 |
GO:0007267 | cell-cell signaling | TAS | | 2408883 |
GO:0009408 | response to heat | IEA | | - |
GO:0007631 | feeding behavior | IEA | | - |
GO:0007566 | embryo implantation | IDA | | 17983652 |
GO:0006954 | inflammatory response | IEA | | - |
GO:0007159 | leukocyte adhesion | IDA | | 1326102 |
GO:0016481 | negative regulation of transcription | IDA | | 11014233 |
GO:0050965 | detection of temperature stimulus involved in sensory perception of pain | IEA | | - |
GO:0032757 | positive regulation of interleukin-8 production | IDA | | 16904178 |
GO:0032730 | positive regulation of interleukin-1 alpha production | IDA | | 16904178 |
GO:0048265 | response to pain | IEA | | - |
GO:0030279 | negative regulation of ossification | IEA | | - |
GO:0031645 | negative regulation of neurological system process | IEA | | - |
GO:0032147 | activation of protein kinase activity | IDA | | 17983652 |
GO:0045779 | negative regulation of bone resorption | IDA | | 10822112 |17241109 |
GO:0045778 | positive regulation of ossification | IEA | | - |
GO:0045651 | positive regulation of macrophage differentiation | IDA | | 10822112 |
GO:0045762 | positive regulation of adenylate cyclase activity | IDA | | 8078488 |11014233 |
GO:0045909 | positive regulation of vasodilation | IDA | | 3266556 |
GO:0045671 | negative regulation of osteoclast differentiation | IDA | | 10822112 |
GO:0043542 | endothelial cell migration | IDA | | 17267696 |
GO:0045986 | negative regulation of smooth muscle contraction | IEA | | - |
GO:0045776 | negative regulation of blood pressure | IDA | | 10642343 |
GO:0051480 | cytosolic calcium ion homeostasis | IDA | | 9685362 |
GO:0051482 | elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | IDA | | 8078488 |9685362 |
Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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GO:0043025 | cell soma | IEA | axon, dendrite (GO term level: 4) | - |
GO:0043195 | terminal button | IEA | axon, Synap, Neurotransmitter (GO term level: 8) | - |
GO:0030424 | axon | IEA | neuron, axon, Neurotransmitter (GO term level: 6) | - |
GO:0005576 | extracellular region | IEA | | - |
GO:0005615 | extracellular space | IDA | | 2408883 |18057382 |
GO:0005622 | intracellular | IEA | | - |
GO:0005737 | cytoplasm | IDA | | 17267696 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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