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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Gene Page: SEMA6D

Summary

GeneID

80031

Symbol

SEMA6D

Synonyms

FLJ11598|KIAA1479

Description

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Locus tag

Gene type

protein-coding

Map location

15q21.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007399

nervous system development

IEA

neurite (GO term level: 5)

GO:0007275

multicellular organismal development

IEA

GO:0016254

preassembly of GPI anchor in ER membrane

EXP

11102867

GO:0030154

cell differentiation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

IEA

GO:0016021

integral to membrane

IEA

GO:0005886

plasma membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
PLXNA1	NOV \| NOVP \| PLEXIN-A1 \| PLXN1	plexin A1	-	HPRD	14977921

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_AXON_GUIDANCE	129	103	All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY	396	292	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_PROTEINS	518	242	All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE	251	188	All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS	26	19	All SZGR genes in this pathway
REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	15	14	All SZGR genes in this pathway
REACTOME_SEMAPHORIN_INTERACTIONS	68	53	All SZGR genes in this pathway
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	188	116	All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI	17	12	All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN	481	290	All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_DN	291	176	All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN	1781	1082	All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	770	415	All SZGR genes in this pathway
PEREZ_TP63_TARGETS	355	243	All SZGR genes in this pathway
LINDGREN_BLADDER_CANCER_CLUSTER_2B	392	251	All SZGR genes in this pathway
SHI_SPARC_TARGETS_UP	24	17	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3	1118	744	All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS	652	441	All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	882	572	All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_UP	175	116	All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_DN	264	168	All SZGR genes in this pathway
FUJII_YBX1_TARGETS_UP	43	28	All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_UP	430	288	All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP	295	149	All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP	141	75	All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	940	425	All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK	1210	725	All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_CLASSICAL	162	122	All SZGR genes in this pathway
PILON_KLF1_TARGETS_UP	504	321	All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN	882	538	All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	1080	713	All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP	116	87	All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D	658	397	All SZGR genes in this pathway
ZWANG_DOWN_BY_2ND_EGF_PULSE	293	119	All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY	1839	928	All SZGR genes in this pathway
NABA_ECM_AFFILIATED	171	89	All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED	753	411	All SZGR genes in this pathway
NABA_MATRISOME	1028	559	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	1495	1502	1A,m8	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-124.1	1293	1299	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	1292	1299	1A,m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	1292	1299	1A,m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-128	942	949	1A,m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	942	949	1A,m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-144	2310	2316	m8	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-15/16/195/424/497	831	838	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-19	414	420	1A	hsa-miR-19a	UGUGCAAAUCUAUGCAAAACUGA
miR-19	414	420	1A	hsa-miR-19b	UGUGCAAAUCCAUGCAAAACUGA
miR-200bc/429	914	920	m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
				hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-221/222	160	166	m8	hsa-miR-221^brain	AGCUACAUUGUCUGCUGGGUUUC
				hsa-miR-222^brain	AGCUACAUCUGGCUACUGGGUCUC
				hsa-miR-221^brain	AGCUACAUUGUCUGCUGGGUUUC
				hsa-miR-222^brain	AGCUACAUCUGGCUACUGGGUCUC
miR-23	1533	1540	1A,m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
				hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
				hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-26	323	330	1A,m8	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	323	330	1A,m8	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-27	943	950	1A,m8	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	943	950	1A,m8	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-299-5p	1990	1996	1A	hsa-miR-299-5p	UGGUUUACCGUCCCACAUACAU
miR-30-5p	664	671	1A,m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-31	861	868	1A,m8	hsa-miR-31	AGGCAAGAUGCUGGCAUAGCUG
miR-31	861	868	1A,m8	hsa-miR-31	AGGCAAGAUGCUGGCAUAGCUG
miR-320	1952	1958	m8	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-323	1532	1539	1A,m8	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-323	1532	1539	1A,m8	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-363	2236	2242	1A	hsa-miR-363	AUUGCACGGUAUCCAUCUGUAA
miR-381	2355	2361	m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-409-3p	1494	1500	m8	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU
miR-496	2404	2411	1A,m8	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-503	832	838	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-505	2167	2173	1A	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC
miR-7	363	369	m8	hsa-miR-7^SZ	UGGAAGACUAGUGAUUUUGUUG
miR-9	116	122	1A	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.