Gene Page: CEP290

Summary
GeneID  80184
Symbol  CEP290
Synonyms  3H11Ag|BBS14|FLJ13615|FLJ21979|JBTS5|JBTS6|KIAA0373|LCA10|MKS4|NPHP6|SLSN6|rd16
Description  centrosomal protein 290kDa
See related  HGNC:29021|MIM:610142|Ensembl:ENSG00000198707|HPRD:08585|HPRD:10856|
Locus tag  -
Gene type  protein-coding
Map location  12q21.32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16682973 
GO:0051011microtubule minus-end bindingIDA16682973 
GO:0016563transcription activator activityIDA16682973 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030902hindbrain developmentISSBrain (GO term level: 8)16682973 
GO:0030030cell projection organizationIEAaxon (GO term level: 7)-
GO:0042462eye photoreceptor cell developmentISS16682973 
GO:0030916otic vesicle formationISS16682973 
GO:0015031protein transportISS-
GO:0048793pronephros developmentISS16682973 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000930gamma-tubulin complexIDA16682973 
GO:0005813centrosomeIDA14654843 
GO:0005829cytosolIDA16682973 
GO:0005634nucleusIDA16682973 
GO:0005737cytoplasmIDA14654843 
GO:0009986cell surfaceIDA12493773 
GO:0005929ciliumIEA-
GO:0032391photoreceptor connecting ciliumISS16682973 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DISC1C1orf136 | FLJ13381 | FLJ21640 | FLJ25311 | FLJ41105 | KIAA0457 | SCZD9disrupted in schizophrenia 1An unspecified isoform of DISC1 interacts with KIAA0373.BIND14623284 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_CELL_CYCLE_MITOTIC 325185All SZGR genes in this pathway
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 6643All SZGR genes in this pathway
REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 5938All SZGR genes in this pathway
REACTOME_MITOTIC_G2_G2_M_PHASES 8150All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP 408247All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
LEE_NEURAL_CREST_STEM_CELL_DN 11879All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
PUJANA_BRCA2_PCC_NETWORK 423265All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_UP 769437All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN 238145All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP 8752All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF 516308All SZGR genes in this pathway


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