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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: GAN

Summary

GeneID

8139

Symbol

GAN

Synonyms

FLJ38059|GAN1|KLHL16

Description

gigaxonin

Locus tag

Gene type

protein-coding

Map location

16q24.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Expression

P value: 1.481

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003674

molecular_function

GO:0005515

protein binding

IPI

12147674 |16227972 |16303566

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006511

ubiquitin-dependent protein catabolic process

IEA

GO:0008150

biological_process

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005883

neurofilament

NAS

neuron, axon (GO term level: 11)

GO:0005856

cytoskeleton

IEA

GO:0005737

cytoplasm

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
MAP1B	DKFZp686E1099 \| DKFZp686F1345 \| FLJ38954 \| FUTSCH \| MAP5	microtubule-associated protein 1B	-	HPRD,BioGRID	12147674
SFN	YWHAS	stratifin	Affinity Capture-MS	BioGRID	15778465

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
REACTOME_IMMUNE_SYSTEM	933	616	All SZGR genes in this pathway
REACTOME_ADAPTIVE_IMMUNE_SYSTEM	539	350	All SZGR genes in this pathway
REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	251	156	All SZGR genes in this pathway
REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	212	129	All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_UP	133	78	All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN	508	354	All SZGR genes in this pathway
ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_UP	63	44	All SZGR genes in this pathway
KENNY_CTNNB1_TARGETS_UP	50	30	All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP	578	341	All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_1_UP	125	61	All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_3_UP	170	97	All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY	1839	928	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	1139	1146	1A,m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-15/16/195/424/497	2425	2431	1A	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-153	400	406	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-17-5p/20/93.mr/106/519.d	2666	2672	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-182	2434	2440	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-196	1138	1144	m8	hsa-miR-196a	UAGGUAGUUUCAUGUUGUUGG
miR-196	1138	1144	m8	hsa-miR-196b	UAGGUAGUUUCCUGUUGUUGG
miR-382	1145	1151	1A	hsa-miR-382^brain	GAAGUUGUUCGUGGUGGAUUCG
miR-448	399	406	1A,m8	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-503	2425	2431	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG
miR-505	181	187	1A	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC
miR-505	181	187	1A	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC
miR-544	2358	2365	1A,m8	hsa-miR-544	AUUCUGCAUUUUUAGCAAGU
miR-96	2433	2440	1A,m8	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.