Gene Page: STX7

Summary
GeneID  8417
Symbol  STX7
Synonyms  -
Description  syntaxin 7
See related  HGNC:11442|MIM:603217|Ensembl:ENSG00000079950|HPRD:04449|
Locus tag  RP11-560I21.1
Gene type  protein-coding
Map location  6q23.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
HS3ST10.670.75
KCNJ110.660.82
SCRT10.660.79
EPHB60.660.75
OSBP20.650.81
POU6F10.640.80
KLC20.640.79
IFFO10.640.79
LRRC40.630.82
ARHGEF110.630.84
Top 10 negatively co-expressed genes
AF347015.21-0.46-0.67
AF347015.31-0.46-0.61
ACSF2-0.44-0.62
MT-CO2-0.44-0.60
S100A16-0.44-0.59
AF347015.8-0.43-0.60
AP002478.3-0.43-0.63
AF347015.2-0.42-0.55
AL139819.3-0.42-0.59
DBI-0.42-0.64
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005484SNAP receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006886intracellular protein transportIEA-
GO:0006892post-Golgi vesicle-mediated transportTAS9358037 
GO:0016192vesicle-mediated transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005768endosomeIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0031901early endosome membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ENTPD2CD39L1 | NTPDase-2ectonucleoside triphosphate diphosphohydrolase 2-HPRD11591653 
NAPASNAPAN-ethylmaleimide-sensitive factor attachment protein, alpha-HPRD,BioGRID9417091 
SNAP29CEDNIK | FLJ21051 | SNAP-29synaptosomal-associated protein, 29kDa-HPRD,BioGRID9852078 |11423532 
STX6-syntaxin 6-HPRD,BioGRID11278762 
STX8CARBsyntaxin 8-HPRD,BioGRID12175335 
VAMP7SYBL1 | TI-VAMP | VAMP-7vesicle-associated membrane protein 7in vitro
in vivo		BioGRID11278762 |12175335 
-HPRD11278762|12175335 
VAMP8EDBvesicle-associated membrane protein 8 (endobrevin)-HPRD,BioGRID11278762 
VPS11END1 | PEP5 | RNF108 | hVPS11vacuolar protein sorting 11 homolog (S. cerevisiae)VPS11 interacts with STX7 (Syntaxin-7). This interaction was modeled on a demonstrated interaction between human VPS11 and STX7 (Syntaxin-7) from an unspecified species.BIND14623309 
-HPRD,BioGRID11382755 
VPS16hVPS16vacuolar protein sorting 16 homolog (S. cerevisiae)-HPRD11382755 
VPS18KIAA1475 | PEP3vacuolar protein sorting 18 homolog (S. cerevisiae)VPS18 interacts with STX7 (Syntaxin-7). This interaction was modeled on a demonstrated interaction between human VPS18 and STX7 (Syntaxin-7) from an unspecified species.BIND14623309 
-HPRD,BioGRID11382755 
VTI1AMVti1 | Vti1-rp2vesicle transport through interaction with t-SNAREs homolog 1A (yeast)Affinity Capture-WesternBioGRID11101518 
VTI1BVTI1 | VTI1-LIKE | VTI1L | VTI2vesicle transport through interaction with t-SNAREs homolog 1B (yeast)-HPRD,BioGRID12114520 |12175335 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 3825All SZGR genes in this pathway
REACTOME_BOTULINUM_NEUROTOXICITY 1914All SZGR genes in this pathway
REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS 1712All SZGR genes in this pathway
REACTOME_NEURONAL_SYSTEM 279221All SZGR genes in this pathway
DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP 332228All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_UP 584356All SZGR genes in this pathway
WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP 7347All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP 3829All SZGR genes in this pathway
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN 165104All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS 775494All SZGR genes in this pathway
GEORGES_TARGETS_OF_MIR192_AND_MIR215 893528All SZGR genes in this pathway
SHEN_SMARCA2_TARGETS_UP 424268All SZGR genes in this pathway
KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN 5842All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN 408274All SZGR genes in this pathway
GENTILE_UV_RESPONSE_CLUSTER_D7 4021All SZGR genes in this pathway
GENTILE_UV_HIGH_DOSE_DN 312203All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_UP 374247All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
JISON_SICKLE_CELL_DISEASE_UP 181106All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_UP 307182All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-361163169m8hsa-miR-361brainUUAUCAGAAUCUCCAGGGGUAC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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