Gene Page: MBTPS1

Summary
GeneID  8720
Symbol  MBTPS1
Synonyms  KIAA0091|MGC138711|MGC138712|PCSK8|S1P|SKI-1
Description  membrane-bound transcription factor peptidase, site 1
See related  HGNC:15456|MIM:603355|Ensembl:ENSG00000140943|HPRD:04522|
Locus tag  -
Gene type  protein-coding
Map location  16|16q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SDPR0.610.64
FGR0.610.57
GATA20.590.57
CXorf360.570.60
C1QTNF10.570.53
HLA-E0.570.57
FAM38A0.570.57
TGM20.570.58
MMRN20.570.57
ERG0.560.57
Top 10 negatively co-expressed genes
TCTEX1D2-0.42-0.46
MED19-0.42-0.43
COQ3-0.41-0.42
UCHL3-0.41-0.42
FRG1-0.40-0.45
OCIAD2-0.40-0.43
C18orf21-0.40-0.43
PSMB7-0.40-0.42
ZNF613-0.40-0.41
C12orf45-0.39-0.44
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004252serine-type endopeptidase activityTASglutamate (GO term level: 7)9809072 
GO:0005509calcium ion bindingIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006508proteolysisTAS9809072 
GO:0008202steroid metabolic processIEA-
GO:0008203cholesterol metabolic processIEA-
GO:0006629lipid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005788endoplasmic reticulum lumenTAS9809072 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005634nucleusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATF6BCREB-RP | CREBL1 | FLJ10066 | G13activating transcription factor 6 beta-HPRD,BioGRID11163209 
CANXCNX | FLJ26570 | IP90 | P90calnexin-HPRD11756446 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DIABETES_PATHWAYS 13391All SZGR genes in this pathway
REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA 139All SZGR genes in this pathway
REACTOME_UNFOLDED_PROTEIN_RESPONSE 8051All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP 11785All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN 196131All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_DN 13797All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP 197135All SZGR genes in this pathway
MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN 6244All SZGR genes in this pathway
AIYAR_COBRA1_TARGETS_UP 3925All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
KAYO_CALORIE_RESTRICTION_MUSCLE_DN 8759All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_UP 439257All SZGR genes in this pathway
GRATIAS_RETINOBLASTOMA_16Q24 1715All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_UP 221150All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP 548370All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.