Gene Page

Home
Datasets
Search
Analysis & Tools
Documents
About SZGR
Quick search: (e.g. 207 or AKT)

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

Release Site Map Support Contact us

Gene Page: SYNJ1

Summary

GeneID

8867

Symbol

SYNJ1

Synonyms

INPP5G

Description

synaptojanin 1

Locus tag

Gene type

protein-coding

Map location

21q22.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 3

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.2637

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003676

nucleic acid binding

IEA

GO:0003723

RNA binding

IEA

GO:0004437

inositol or phosphatidylinositol phosphatase activity

IEA

GO:0004439

phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

IEA

GO:0004445

inositol-polyphosphate 5-phosphatase activity

TAS

9428629

GO:0016787

hydrolase activity

IEA

GO:0017120

polyphosphoinositide phosphatase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0048489

synaptic vesicle transport

IEA

neuron, Synap (GO term level: 6)

GO:0048488

synaptic vesicle endocytosis

TAS

axon, Synap, Neurotransmitter (GO term level: 7)

9428629

GO:0006836

neurotransmitter transport

IEA

neuron, Neurotransmitter (GO term level: 5)

GO:0006796

phosphate metabolic process

TAS

9428629

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005737

cytoplasm

IEA

GO:0030117

membrane coat

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AMPH	AMPH1	amphiphysin	-	HPRD	10542231 \|14704270
AMPH	AMPH1	amphiphysin	Affinity Capture-Western Reconstituted Complex	BioGRID	9341169
BIN1	AMPH2 \| AMPHL \| DKFZp547F068 \| MGC10367 \| SH3P9	bridging integrator 1	-	HPRD,BioGRID	9195986 \|9341169
FNBP4	DKFZp686M14102 \| DKFZp779I1064 \| FBP30 \| FLJ41904 \| KIAA1014	formin binding protein 4	-	HPRD	11292345
PACSIN1	KIAA1379 \| SDPI	protein kinase C and casein kinase substrate in neurons 1	Reconstituted Complex	BioGRID	11082044
PACSIN2	SDPII	protein kinase C and casein kinase substrate in neurons 2	Reconstituted Complex	BioGRID	11082044
PACSIN3	SDPIII	protein kinase C and casein kinase substrate in neurons 3	Reconstituted Complex	BioGRID	11082044
SH3BP1	-	SH3-domain binding protein 1	-	HPRD	10764144
SH3GL2	CNSA2 \| EEN-B1 \| FLJ20276 \| FLJ25015 \| SH3D2A \| SH3P4	SH3-domain GRB2-like 2	Affinity Capture-Western Reconstituted Complex	BioGRID	9341169
SH3GLB1	Bif-1 \| CGI-61 \| KIAA0491 \| dJ612B15.2	SH3-domain GRB2-like endophilin B1	-	HPRD	14704270
SH3KBP1	CIN85 \| GIG10 \| MIG18	SH3-domain kinase binding protein 1	Affinity Capture-Western Far Western	BioGRID	12829691

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
KEGG_INOSITOL_PHOSPHATE_METABOLISM	54	42	All SZGR genes in this pathway
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM	76	56	All SZGR genes in this pathway
BIOCARTA_NDKDYNAMIN_PATHWAY	21	15	All SZGR genes in this pathway
PID_EPHB_FWD_PATHWAY	40	38	All SZGR genes in this pathway
PID_ERBB1_INTERNALIZATION_PATHWAY	41	35	All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM	198	112	All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	31	23	All SZGR genes in this pathway
REACTOME_PI_METABOLISM	48	34	All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS	478	302	All SZGR genes in this pathway
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN	145	91	All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_MATURE_CELL	293	160	All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN	1237	837	All SZGR genes in this pathway
WANG_CISPLATIN_RESPONSE_AND_XPC_DN	228	146	All SZGR genes in this pathway
MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP	83	49	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_UP	156	101	All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP	953	554	All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP	783	442	All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP	578	341	All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_DN	145	93	All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK	1210	725	All SZGR genes in this pathway
PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP	193	95	All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN	253	192	All SZGR genes in this pathway
NIELSEN_GIST	98	66	All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_UP	548	370	All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN	1972	1213	All SZGR genes in this pathway
CERIBELLI_GENES_INACTIVE_AND_BOUND_BY_NFY	45	27	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	1108	1114	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	1108	1114	m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-142-5p	2134	2141	1A,m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-148/152	99	106	1A,m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
				hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-15/16/195/424/497	1109	1115	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-153	1175	1181	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-190	2182	2188	m8	hsa-miR-190	UGAUAUGUUUGAUAUAUUAGGU
miR-200bc/429	1678	1685	1A,m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
				hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-203.1	1652	1658	1A	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-218	1471	1477	m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-23	1705	1712	1A,m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	1705	1712	1A,m8	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-25/32/92/363/367	79	86	1A,m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-323	1705	1711	1A	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-34/449	1166	1173	1A,m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-365	59	66	1A,m8	hsa-miR-365	UAAUGCCCCUAAAAAUCCUUAU
miR-378	1896	1902	1A	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU
miR-448	1174	1181	1A,m8	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-9	392	399	1A,m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.