Gene Page: SYNJ2

Summary
GeneID  8871
Symbol  SYNJ2
Synonyms  INPP5H|KIAA0348|MGC44422
Description  synaptojanin 2
See related  HGNC:11504|MIM:609410|Ensembl:ENSG00000078269|HPRD:10259|
Locus tag  RP11-266C7.2
Gene type  protein-coding
Map location  6q25.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRIM280.950.94
HNRNPA00.930.90
SMARCB10.930.91
HNRNPM0.930.86
HNRNPL0.930.92
DBN10.930.91
CENPV0.930.93
DDX390.920.90
PPP4C0.920.92
RBM40.920.91
Top 10 negatively co-expressed genes
HLA-F-0.71-0.76
AF347015.27-0.70-0.88
AF347015.33-0.69-0.88
C5orf53-0.69-0.73
AF347015.31-0.69-0.86
MT-CO2-0.68-0.87
AIFM3-0.68-0.75
MT-CYB-0.68-0.88
S100B-0.67-0.80
AF347015.8-0.66-0.88
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003723RNA bindingIEA-
GO:0004437inositol or phosphatidylinositol phosphatase activityIEA-
GO:0004439phosphatidylinositol-4,5-bisphosphate 5-phosphatase activityIEA-
GO:0016787hydrolase activityIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2-HPRD9388224 
ITSN2KIAA1256 | PRO2015 | SH3D1B | SH3P18 | SWA | SWAPintersectin 2-HPRD12421765 
NCK1MGC12668 | NCK | NCKalphaNCK adaptor protein 1-HPRD10805734 
RAC1MGC111543 | MIG5 | TC-25 | p21-Rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-HPRD,BioGRID11084340 
SFNYWHASstratifinAffinity Capture-MSBioGRID15778465 
SH3GL2CNSA2 | EEN-B1 | FLJ20276 | FLJ25015 | SH3D2A | SH3P4SH3-domain GRB2-like 2Reconstituted ComplexBioGRID12456676 
SYNJ2BPARIP2 | FLJ11271 | FLJ41973 | OMP25synaptojanin 2 binding protein-HPRD,BioGRID10357812 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_INOSITOL_PHOSPHATE_METABOLISM 5442All SZGR genes in this pathway
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 7656All SZGR genes in this pathway
BIOCARTA_NDKDYNAMIN_PATHWAY 2115All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM 198112All SZGR genes in this pathway
REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 3123All SZGR genes in this pathway
REACTOME_PI_METABOLISM 4834All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP 183119All SZGR genes in this pathway
HUTTMANN_B_CLL_POOR_SURVIVAL_DN 6039All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN 14383All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN 7746All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP 239157All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN 8463All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN 855609All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_DN 160110All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_14HR_DN 298200All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_DN 7657All SZGR genes in this pathway
SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP 3427All SZGR genes in this pathway
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 419273All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 482296All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
BOYAULT_LIVER_CANCER_SUBCLASS_G12_UP 3917All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP 178108All SZGR genes in this pathway
MIKKELSEN_ES_ICP_WITH_H3K4ME3 718401All SZGR genes in this pathway
MIKKELSEN_NPC_ICP_WITH_H3K4ME3 445257All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF 516308All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/206551557m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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