Gene Page: CDK5R2

Summary
GeneID  8941
Symbol  CDK5R2
Synonyms  NCK5AI|P39|p39nck5ai
Description  cyclin-dependent kinase 5, regulatory subunit 2 (p39)
See related  HGNC:1776|MIM:603764|Ensembl:ENSG00000171450|HPRD:04790|
Locus tag  -
Gene type  protein-coding
Map location  2q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ANAPC10.890.88
UGCG0.880.88
ARMC80.880.84
STAM0.880.83
PSMD50.880.86
LMBR10.870.88
KIAA10120.870.85
AKAP100.870.87
KIAA14680.870.88
TMEM184C0.870.84
Top 10 negatively co-expressed genes
MT-CO2-0.75-0.64
AF347015.21-0.75-0.64
AF347015.8-0.73-0.64
HIGD1B-0.73-0.66
AF347015.2-0.72-0.60
AF347015.31-0.72-0.62
MT-CYB-0.71-0.60
AC098691.2-0.70-0.69
AF347015.18-0.70-0.64
AF347015.33-0.70-0.59
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0016534cyclin-dependent protein kinase 5 activator activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000079regulation of cyclin-dependent protein kinase activityTAS7592934 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016533cyclin-dependent protein kinase 5 activator complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTN1FLJ40884actinin, alpha 1-HPRD,BioGRID12223541 
CDK5PSSALREcyclin-dependent kinase 5-HPRD,BioGRID10683146 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_LIS1_PATHWAY 2822All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 210148All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1336167m8hsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-3311371431Ahsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-9611421148m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.