Gene Page: IL1RL1

Summary
GeneID  9173
Symbol  IL1RL1
Synonyms  DER4|FIT-1|MGC32623|ST2|ST2L|ST2V|T1
Description  interleukin 1 receptor-like 1
See related  HGNC:5998|MIM:601203|Ensembl:ENSG00000115602|HPRD:03123|
Locus tag  -
Gene type  protein-coding
Map location  2q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ANKRD440.910.92
RRP1B0.910.92
SEC24A0.910.95
PRRC10.900.92
SPAST0.900.94
IGSF30.900.89
URB20.900.92
EPM2AIP10.900.93
MFHAS10.900.90
ZXDA0.900.92
Top 10 negatively co-expressed genes
FXYD1-0.66-0.84
AF347015.31-0.64-0.81
MT-CO2-0.64-0.82
IFI27-0.63-0.80
C5orf53-0.63-0.71
AF347015.33-0.63-0.79
CXCL14-0.62-0.82
AF347015.27-0.62-0.78
HIGD1B-0.62-0.80
HLA-F-0.61-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005057receptor signaling protein activityTAS1482686 
GO:0004888transmembrane receptor activityIEA-
GO:0005515protein bindingIPI16286016 
GO:0004908interleukin-1 receptor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionTAS1482686 
GO:0045087innate immune responseIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005813centrosomeIDA18029348 
GO:0005576extracellular regionIEA-
GO:0005737cytoplasmIDA18029348 
GO:0016021integral to membraneIEA-
GO:0005925focal adhesionIDA18029348 
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
TMED1IL1RL1LG | Il1rl1l | MGC1270 | ST2Ltransmembrane emp24 protein transport domain containing 1-HPRD,BioGRID8621446 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP 185126All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN 5135All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP 12672All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP 12073All SZGR genes in this pathway
MARKEY_RB1_CHRONIC_LOF_UP 11578All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_DN 2518All SZGR genes in this pathway
HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP 6445All SZGR genes in this pathway
WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN 5529All SZGR genes in this pathway
SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION 5031All SZGR genes in this pathway
LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_DN 4524All SZGR genes in this pathway
RICKMAN_HEAD_AND_NECK_CANCER_C 11347All SZGR genes in this pathway
OKUMURA_INFLAMMATORY_RESPONSE_LPS 183115All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FLI1 98All SZGR genes in this pathway
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP 8864All SZGR genes in this pathway
AFFAR_YY1_TARGETS_DN 234137All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR 544307All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_NHEK_UP 244151All SZGR genes in this pathway
BURTON_ADIPOGENESIS_2 7252All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_UP 178111All SZGR genes in this pathway
HAN_JNK_SINGALING_UP 3521All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_8HR 3931All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP 393244All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_P4 10062All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP 295149All SZGR genes in this pathway
ZHENG_IL22_SIGNALING_DN 4226All SZGR genes in this pathway
MATTHEWS_AP1_TARGETS 1712All SZGR genes in this pathway
ALONSO_METASTASIS_UP 198128All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_DN 252155All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
DAZARD_UV_RESPONSE_CLUSTER_G24 2819All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_C 9260All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP 271165All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
KATSANOU_ELAVL1_TARGETS_DN 14888All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_UP 199143All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
DURAND_STROMA_S_UP 297194All SZGR genes in this pathway


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