Gene Page: ZW10

Summary
GeneID  9183
Symbol  ZW10
Synonyms  HZW10|KNTC1AP|MGC149821
Description  ZW10, kinetochore associated, homolog (Drosophila)
See related  HGNC:13194|MIM:603954|Ensembl:ENSG00000086827|HPRD:04902|
Locus tag  -
Gene type  protein-coding
Map location  11q23.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LRMP0.620.65
KLK70.550.54
C13orf360.540.64
CCDC28A0.520.54
POPDC30.520.63
HPRT10.510.54
AC090772.40.500.51
MAPK30.490.54
AC008670.20.490.35
TSPAN160.490.32
Top 10 negatively co-expressed genes
HYAL2-0.38-0.48
TBC1D16-0.38-0.43
TES-0.38-0.50
SMTN-0.37-0.46
SH3BP2-0.36-0.51
GLIS2-0.36-0.44
CBX8-0.36-0.35
FLT4-0.36-0.42
SBNO2-0.36-0.42
LRP5-0.36-0.45
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI11146660 |12686595 
GO:0019237centromeric DNA bindingTAS9700164 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000070mitotic sister chromatid segregationIDA11146660 
GO:0006461protein complex assemblyIDA11146660 
GO:0007049cell cycleIEA-
GO:0007093mitotic cell cycle checkpointIDA11146660 
GO:0007096regulation of exit from mitosisIDA11146660 
GO:0007126meiosisTAS9298984 
GO:0006888ER to Golgi vesicle-mediated transportIMP15029241 
GO:0016192vesicle-mediated transportIEA-
GO:0015031protein transportIEA-
GO:0051301cell divisionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000777condensed chromosome kinetochoreIEA-
GO:0000922spindle poleIDA11146660 
GO:0005828kinetochore microtubuleIDA11146660 
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005634nucleusIDA15485811 
GO:0005737cytoplasmIEA-
GO:0005783endoplasmic reticulumIDA15029241 
GO:0016020membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GSTK1GST13glutathione S-transferase kappa 1Affinity Capture-MSBioGRID17353931 
KNTC1FLJ36151 | KIAA0166 | RODkinetochore associated 1-HPRD,BioGRID11146660 
PHLDA3TIH1pleckstrin homology-like domain, family A, member 3Affinity Capture-MSBioGRID17353931 
RINT1DKFZp667H2324 | RINT-1RAD50 interactor 1-HPRD,BioGRID15029241 
STX18DKFZp686O15149 | Ufe1syntaxin 18Affinity Capture-MS
Affinity Capture-Western
BioGRID15029241 
ZWINTHZwint-1 | KNTC2AP | MGC117174 | ZWINT1ZW10 interactor-HPRD10806105 |15485811 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_CELL_CYCLE 421253All SZGR genes in this pathway
REACTOME_CELL_CYCLE_MITOTIC 325185All SZGR genes in this pathway
REACTOME_MITOTIC_M_M_G1_PHASES 17298All SZGR genes in this pathway
REACTOME_DNA_REPLICATION 192110All SZGR genes in this pathway
REACTOME_MITOTIC_PROMETAPHASE 8751All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_18HR_UP 178111All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN 5734All SZGR genes in this pathway
LU_EZH2_TARGETS_UP 295155All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
RAO_BOUND_BY_SALL4_ISOFORM_B 517302All SZGR genes in this pathway


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