Gene Page: TAOK2

Summary
GeneID  9344
Symbol  TAOK2
Synonyms  KIAA0881|MAP3K17|PSK|PSK1|TAO1|TAO2
Description  TAO kinase 2
See related  HGNC:16835|Ensembl:ENSG00000149930|HPRD:18147|
Locus tag  -
Gene type  protein-coding
Map location  16p11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01775 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIEA-
GO:0005524ATP bindingIEA-
GO:0004674protein serine/threonine kinase activityIDA10660600 
GO:0004674protein serine/threonine kinase activityIEA-
GO:0016740transferase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000186activation of MAPKK activityIDA10660600 
GO:0001558regulation of cell growthNAS10660600 
GO:0006468protein amino acid phosphorylationIEA-
GO:0006950response to stressIDA10660600 
GO:0008360regulation of cell shapeIDA10660600 
GO:0048041focal adhesion formationIDA10660600 
GO:0006915apoptosisNAS10660600 
GO:0006612protein targeting to membraneNAS10660600 
GO:0016477cell migrationNAS10660600 
GO:0030036actin cytoskeleton organizationIDA10660600 
GO:0046330positive regulation of JNK cascadeIDA10660600 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0030659cytoplasmic vesicle membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAP2K3MAPKK3 | MEK3 | MKK3 | PRKMK3mitogen-activated protein kinase kinase 3-HPRD10497253 |11279118 
-HPRD,BioGRID9786855 
MAP2K6MAPKK6 | MEK6 | MKK6 | PRKMK6 | SAPKK3mitogen-activated protein kinase kinase 6Affinity Capture-Western
Biochemical Activity		BioGRID11279118 
MEGF10DKFZp781K1852 | FLJ41574 | KIAA1780multiple EGF-like-domains 10-HPRD12421765 
TUBA4AFLJ30169 | H2-ALPHA | TUBA1tubulin, alpha 4a-HPRD12639963 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2A-HPRD12639963 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_MAPK_SIGNALING_PATHWAY 267205All SZGR genes in this pathway
PID_P38_MKK3_6PATHWAY 2621All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP 544308All SZGR genes in this pathway
EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP 207128All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP 390242All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_UP 210124All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_2D_UP 6946All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1431321391A,m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-1513163221Ahsa-miR-151brainACUAGACUGAAGCUCCUUGAGG
miR-193156162m8hsa-miR-193aAACUGGCCUACAAAGUCCCAG
hsa-miR-193bAACUGGCCCUCAAAGUCCCGCUUU
miR-204/2115695751Ahsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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