Gene Page: MED23

Summary
GeneID  9439
Symbol  MED23
Synonyms  CRSP130|CRSP133|CRSP3|DKFZp434H0117|DRIP130|SUR2
Description  mediator complex subunit 23
See related  HGNC:2372|MIM:605042|Ensembl:ENSG00000112282|HPRD:05436|
Locus tag  RP5-914N13.2
Gene type  protein-coding
Map location  6q22.33-q24.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SYNJ10.950.93
GABRG20.950.93
NCOA70.950.92
GLS0.950.93
ATP6V1A0.940.92
FAM179B0.940.88
PIK3CB0.930.94
NSF0.930.90
ARFGEF20.930.89
MAP2K40.930.92
Top 10 negatively co-expressed genes
EFEMP2-0.47-0.53
RAB34-0.47-0.57
C1orf61-0.44-0.59
IRF7-0.43-0.56
GATSL3-0.42-0.46
AL022328.1-0.42-0.53
DBI-0.41-0.47
AC006276.2-0.41-0.41
CLEC3B-0.41-0.52
RAB13-0.41-0.50
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003713transcription coactivator activityTAS9989412 
GO:0005515protein bindingIPI17438371 
GO:0030528transcription regulator activityIDA9989412 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006367transcription initiation from RNA polymerase II promoterTAS9989412 
GO:0006357regulation of transcription from RNA polymerase II promoterTAS9989412 
GO:0006350transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005667transcription factor complexIDA9989412 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onsetAffinity Capture-MSBioGRID15208681 
CDK8K35 | MGC126074 | MGC126075cyclin-dependent kinase 8Affinity Capture-WesternBioGRID11416138 
CEBPBC/EBP-beta | CRP2 | IL6DBP | LAP | MGC32080 | NF-IL6 | TCF5CCAAT/enhancer binding protein (C/EBP), beta-HPRD,BioGRID14759369 
ELF3EPR-1 | ERT | ESE-1 | ESXE74-like factor 3 (ets domain transcription factor, epithelial-specific )-HPRD,BioGRID12242338 
FOXJ3MGC165036 | MGC176686forkhead box J3-HPRD12421765 
HNF4AFLJ39654 | HNF4 | HNF4a7 | HNF4a8 | HNF4a9 | MODY | MODY1 | NR2A1 | NR2A21 | TCF | TCF14hepatocyte nuclear factor 4, alphaAffinity Capture-WesternBioGRID12089346 
IRF1IRF-1 | MARinterferon regulatory factor 1An unspecified isoform of MED23 interacts with IRF-1 promoter.BIND15893730 
MED10L6 | MGC5309 | NUT2 | TRG20mediator complex subunit 10Affinity Capture-MSBioGRID15175163 
MED19DT2P1G7 | LCMR1mediator complex subunit 19Affinity Capture-MSBioGRID15175163 
MED26CRSP7 | CRSP70mediator complex subunit 26Affinity Capture-MSBioGRID15175163 
MED281500003D12Rik | DKFZp434N185 | EG1 | magicinmediator complex subunit 28Affinity Capture-MSBioGRID15175163 
MED29DKFZp434H247 | IXLmediator complex subunit 29-HPRD14576168 
Affinity Capture-MSBioGRID15175163 
MED9FLJ10193 | MED25 | MGC138234mediator complex subunit 9-HPRD14638676 
Affinity Capture-MSBioGRID15175163 
NCOA6AIB3 | ANTP | ASC2 | HOX1.1 | HOXA7 | KIAA0181 | NRC | PRIP | RAP250 | TRBPnuclear receptor coactivator 6-HPRD,BioGRID10823961 
WDTC1ADP | KIAA1037 | RP11-4K3__A.1WD and tetratricopeptide repeats 1-HPRD12421765 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 10472All SZGR genes in this pathway
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 352181All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 168115All SZGR genes in this pathway
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 7253All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN 805505All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
RAMALHO_STEMNESS_UP 206118All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
MA_PITUITARY_FETAL_VS_ADULT_DN 1917All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP 12589All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP 10457All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BILANGES_RAPAMYCIN_SENSITIVE_GENES 3920All SZGR genes in this pathway


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