Gene Page: ITM2B

Summary
GeneID  9445
Symbol  ITM2B
Synonyms  ABRI|BRI|BRI2|BRICD2B|E25B|E3-16|FBD
Description  integral membrane protein 2B
See related  HGNC:6174|MIM:603904|Ensembl:ENSG00000136156|HPRD:04878|
Locus tag  RP11-196P14.1
Gene type  protein-coding
Map location  13q14.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
STX50.930.92
DHPS0.930.93
ARMC60.920.92
DCTN20.920.92
PSMD30.920.92
TINF20.920.91
RPUSD40.910.92
DEDD0.910.91
ACTR1A0.910.91
PRMT10.910.90
Top 10 negatively co-expressed genes
AF347015.33-0.76-0.84
AF347015.8-0.76-0.85
MT-CO2-0.76-0.82
MT-CYB-0.75-0.83
AF347015.27-0.75-0.83
AF347015.31-0.75-0.81
AF347015.26-0.74-0.86
AF347015.15-0.74-0.83
AF347015.2-0.72-0.81
HEPN1-0.69-0.76
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)10391242 
GO:0006917induction of apoptosisIEA-
GO:0007605sensory perception of soundIEA-
GO:0006915apoptosisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BCL2Bcl-2B-cell CLL/lymphoma 2-HPRD,BioGRID12082633 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_AMYLOIDS 8363All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN 391222All SZGR genes in this pathway
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP 177110All SZGR genes in this pathway
WANG_CLIM2_TARGETS_DN 186114All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
LUI_THYROID_CANCER_PAX8_PPARG_DN 4529All SZGR genes in this pathway
LUI_THYROID_CANCER_CLUSTER_3 2816All SZGR genes in this pathway
LUI_TARGETS_OF_PAX8_PPARG_FUSION 3423All SZGR genes in this pathway
DACOSTA_UV_RESPONSE_VIA_ERCC3_UP 309199All SZGR genes in this pathway
JOHANSSON_BRAIN_CANCER_EARLY_VS_LATE_DN 4535All SZGR genes in this pathway
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN 584395All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP 487286All SZGR genes in this pathway
GNATENKO_PLATELET_SIGNATURE 4828All SZGR genes in this pathway
SHEPARD_BMYB_MORPHOLINO_UP 205126All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
PARK_HSC_AND_MULTIPOTENT_PROGENITORS 5033All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP 182119All SZGR genes in this pathway
XU_RESPONSE_TO_TRETINOIN_UP 1610All SZGR genes in this pathway
IGLESIAS_E2F_TARGETS_UP 151103All SZGR genes in this pathway
KAAB_FAILED_HEART_ATRIUM_DN 14199All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP 7149All SZGR genes in this pathway
SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_DN 2915All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_UP 12375All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
GAVIN_FOXP3_TARGETS_CLUSTER_T7 9863All SZGR genes in this pathway
ZHENG_BOUND_BY_FOXP3 491310All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_STIMULATED 1022619All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP 3122All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
BOCHKIS_FOXA2_TARGETS 425261All SZGR genes in this pathway
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN 159105All SZGR genes in this pathway
WANG_TUMOR_INVASIVENESS_DN 210128All SZGR genes in this pathway
HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS 8056All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
YAGI_AML_WITH_T_8_21_TRANSLOCATION 368247All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_DN 253192All SZGR genes in this pathway
KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_DN 4631All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_1_DN 1713All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN 448282All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_UP 16697All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1431281351A,m8hsa-miR-143brainUGAGAUGAAGCACUGUAGCUCA
miR-2243723791A,m8hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-324-3p67731Ahsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
miR-4521051111Ahsa-miR-452UGUUUGCAGAGGAAACUGAGAC
miR-49695101m8hsa-miR-496AUUACAUGGCCAAUCUC
miR-96806871A,m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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