Gene Page: ENTPD4

Summary
GeneID  9583
Symbol  ENTPD4
Synonyms  KIAA0392|LALP70|LAP70|LYSAL1|NTPDase-4|UDPase
Description  ectonucleoside triphosphate diphosphohydrolase 4
See related  HGNC:14573|MIM:607577|Ensembl:ENSG00000197217|HPRD:09618|
Locus tag  -
Gene type  protein-coding
Map location  8p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FURIN0.910.91
MAPK8IP30.890.90
LRRC680.890.89
SGSM20.890.89
MLLT60.890.89
SPTBN20.890.90
POU6F10.880.89
SBF10.880.88
JPH30.880.90
TTBK10.880.90
Top 10 negatively co-expressed genes
AF347015.21-0.68-0.58
GNG11-0.63-0.60
C1orf54-0.62-0.62
AF347015.31-0.59-0.51
MT-CO2-0.57-0.49
AL050337.1-0.56-0.54
AL139819.3-0.56-0.56
SYCP3-0.55-0.54
AF347015.8-0.55-0.46
CLEC2B-0.54-0.52
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000287magnesium ion bindingIEA-
GO:0005509calcium ion bindingIEA-
GO:0016787hydrolase activityIEA-
GO:0045134uridine-diphosphatase activityIDA9556635 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006256UDP catabolic processIDA9556635 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0030173integral to Golgi membraneIDA9556635 
GO:0031410cytoplasmic vesicleIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PURINE_METABOLISM 15996All SZGR genes in this pathway
KEGG_PYRIMIDINE_METABOLISM 9853All SZGR genes in this pathway
KEGG_LYSOSOME 12183All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN 320184All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_24HR_UP 557331All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_DN 1024594All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
HADDAD_B_LYMPHOCYTE_PROGENITOR 293193All SZGR genes in this pathway
HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP 6544All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 720440All SZGR genes in this pathway
KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP 9362All SZGR genes in this pathway
LU_EZH2_TARGETS_DN 414237All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-125/3514854m8hsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-1353541m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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