Gene Page: FEZ2

Summary
GeneID  9637
Symbol  FEZ2
Synonyms  HUM3CL|MGC117372
Description  fasciculation and elongation protein zeta 2 (zygin II)
See related  HGNC:3660|MIM:604826|HPRD:09213|
Locus tag  -
Gene type  protein-coding
Map location  2p21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SEC16A0.930.95
ZFYVE260.920.94
KIAA13100.920.94
ANKFY10.910.94
TRRAP0.910.94
USP220.910.94
TGFBRAP10.910.95
CRAMP1L0.910.94
HCFC10.910.92
URB10.910.94
Top 10 negatively co-expressed genes
AF347015.31-0.68-0.82
MT-CO2-0.68-0.83
AF347015.27-0.66-0.78
FXYD1-0.65-0.79
AF347015.33-0.64-0.76
AF347015.8-0.64-0.81
AF347015.21-0.64-0.88
HIGD1B-0.64-0.80
IFI27-0.64-0.76
MT-CYB-0.64-0.77
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI14690447 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007411axon guidanceTASaxon (GO term level: 13)9096408 
GO:0007399nervous system developmentTASneurite (GO term level: 5)9096408 
GO:0007165signal transductionTAS9096408 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NEK1DKFZp686D06121 | DKFZp686K12169 | KIAA1901 | MGC138800 | NY-REN-55NIMA (never in mitosis gene a)-related kinase 1NEK1 interacts with FEZ-2.BIND14690447 
PRKCZPKC-ZETA | PKC2protein kinase C, zeta-HPRD,BioGRID14697253 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN 460312All SZGR genes in this pathway
WANG_LMO4_TARGETS_DN 352225All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
LANDIS_BREAST_CANCER_PROGRESSION_DN 7043All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN 2921All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
LANDIS_ERBB2_BREAST_TUMORS_324_DN 14993All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP 157105All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN 225163All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_NO_BLOOD_UP 222139All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
LEIN_CEREBELLUM_MARKERS 8547All SZGR genes in this pathway
FOSTER_TOLERANT_MACROPHAGE_DN 409268All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
DANG_REGULATED_BY_MYC_UP 7253All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 7947All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-200bc/4291211281A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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