| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1452 |
Name | CSNK1A1 |
Synonym | CK1|CK1a|CKIa|HEL-S-77p|HLCDGP1|PRO2975;casein kinase 1, alpha 1;CSNK1A1;casein kinase 1, alpha 1 |
Definition | CKI-alpha|casein kinase I isoform alpha|clock regulator kinase|down-regulated in lung cancer|epididymis secretory sperm binding protein Li 77p |
Position | 5q32 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 5450 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Hedgehog signaling events mediated by Gli proteins;PID Curated;200147 |
Pathway | Parkinson disease;PANTHER;P00049 |
Pathway | Presenilin action in Notch and Wnt signaling;PID Curated;200052 |
Pathway | Hedgehog signaling pathway;PANTHER;P00025 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Signaling by Wnt;Reactome;REACT:11045 |
Pathway | Noncanonical Wnt signaling pathway;PID Curated;200016 |
Pathway | Degradation of beta-catenin by the destruction complex;PID Reactome;500310 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | Hedgehog signaling pathway;KEGG PATHWAY;hsa04340 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | p53 pathway;PID Curated;200175 |
Disease | Breast cancer;FunDO |
Disease | Leukoencephalopathy;FunDO |
|
External Links |
|
Links to Entrez Gene | 1452 |
Links to all GeneRIF Items | 1452 |
Links to iHOP | 1452 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>1452 : length: 1098 atggcgagtagcagcggctccaaggctgaattcattgtcggagggaaatataaactggta cggaagatcgggtctggctccttcggggacatctatttggcgatcaacatcaccaacggc gaggaagtggcagtgaagctagaatctcagaaggccaggcatccccagttgctgtacgag agcaagctctataagattcttcaaggtggggttggcatcccccacatacggtggtatggt caggaaaaagactacaatgtactagtcatggatcttctgggacctagcctcgaagacctc ttcaatttctgttcaagaaggttcacaatgaaaactgtacttatgttagctgaccagatg atcagtagaattgaatatgtgcatacaaagaattttatacacagagacattaaaccagat aacttcctaatgggtattgggcgtcactgtaataagtgtttagaatctccagtggggaag aggaaaagaagcatgactgttagtacttctcaggacccatctttctcaggattaaaccag ttattccttattgattttggtttggccaaaaagtacagagacaacaggacaaggcaacac ataccatacagagaagataaaaacctcactggcactgcccgatatgctagcatcaatgca catcttggtattgagcagagtcgccgagatgacatggaatcattaggatatgttttgatg tattttaatagaaccagcctgccatggcaagggctaaaggctgcaacaaagaaacaaaaa tatgaaaagattagtgaaaagaagatgtccacgcctgttgaagttttatgtaaggggttt cctgcagaatttgcgatgtacttaaactattgtcgtgggctacgctttgaggaagcccca gattacatgtatctgaggcagctattccgcattcttttcaggaccctgaaccatcaatat gactacacatttgattggacaatgttaaagcagaaagcagcacagcaggcagcctcttcc agtgggcagggtcagcaggcccaaacccccacaggcaagcaaactgacaaaaccaagagt aacatgaaaggtttctaa |
Protein Sequence |
>1452 : length: 365 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQ LFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLM YFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAP DYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKS NMKGF |