Entrez Gene

Basic Information
Gene ID	1452
Name	CSNK1A1
Synonymous	CK1\|CK1a\|CKIa\|HEL-S-77p\|HLCDGP1\|PRO2975;casein kinase 1, alpha 1;CSNK1A1;casein kinase 1, alpha 1
Definition	CKI-alpha\|casein kinase I isoform alpha\|clock regulator kinase\|down-regulated in lung cancer\|epididymis secretory sperm binding protein Li 77p
Position	5q32
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
NF-AT4(h) + CKI-alpha(h) <==> NF-AT4(h):CKI-alpha(h) (binding)
FADD(h) + CKI-alpha(h) <==> FADD(h):CKI-alpha(h) (binding)
CKI-alpha(h) + Mdm4(h) <==> CKI-alpha(h):Mdm4(h) (binding)
CKI-alpha(h) + mdm2(m.s.) <==> CKI-alpha(h):mdm2(m.s.) (binding)
CKI-alpha(h) + p53(m.s.) <==> CKI-alpha(h):p53(m.s.) (binding)
CKI-alpha(h) + Mdm4(h) <==> CKI-alpha(h):Mdm4(h) (binding)
CKI-alpha(h) --> HCV-NS5A-1B-Con1(HCV1BCon1){p}n (increase of phosphorylation)
RIP(h) + CKI-alpha(h) <==> RIP(h):CKI-alpha(h) (binding)
NF-AT4(h):CKI-alpha(h) + ATP --> NF-AT4(h){p} + CKI-alpha(h) + ADP (phosphorylation; dissociation)
CSNK1A1(h) --> CKI-alpha(h) (expression).
Bid(m) + ATP --CKI-alpha(h)--> Bid(m){p} + ADP (phosphorylation)
FADD(h) + ATP --CKI-alpha(h)--> FADD(h){pS194} + ADP (phosphorylation)
Mdm4(h) + ATP --CKI-alpha(h)--> Mdm4(h){pS289} + ADP (phosphorylation)
HCV-NS5A-1A-H(HCV1AH) + n ATP --CKI-alpha(h)--> HCV-NS5A-1A-H(HCV1AH){p}n + n ADP (phosphorylation)
CSNK1A1(h) --> CKI-alpha(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
321	Phosphothreonine.		Swiss-Prot 53.0
321	Phosphothreonine	16565220	Phospho.ELM 6.0