| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2042 |
Name | EPHA3 |
Synonym | EK4|ETK|ETK1|HEK|HEK4|TYRO4;EPH receptor A3;EPHA3;EPH receptor A3 |
Definition | EPH-like kinase 4|TYRO4 protein tyrosine kinase|eph-like tyrosine kinase 1|ephrin type-A receptor 3|human embryo kinase 1|tyrosine-protein kinase receptor ETK1 |
Position | 3p11.2 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 6574 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | EPHA forward signaling;PID Curated;200121 |
Pathway | Angiogenesis;PANTHER;P00005 |
Disease | Lung cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 2042 |
Links to all GeneRIF Items | 2042 |
Links to iHOP | 2042 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>2042 : length: 2952 atggattgtcagctctccatcctcctccttctcagctgctctgttctcgacagcttcggg gaactgattccgcagccttccaatgaagtcaatctactggattcaaaaacaattcaaggg gagctgggctggatctcttatccatcacatgggtgggaagagatcagtggtgtggatgaa cattacacacccatcaggacttaccaggtgtgcaatgtcatggaccacagtcaaaacaat tggctgagaacaaactgggtccccaggaactcagctcagaagatttatgtggagctcaag ttcactctacgagactgcaatagcattccattggttttaggaacttgcaaggagacattc aacctgtactacatggagtctgatgatgatcatggggtgaaatttcgagagcatcagttt acaaagattgacaccattgcagctgatgaaagtttcactcaaatggatcttggggaccgt attctgaagctcaacactgagattagagaagtaggtcctgtcaacaagaagggattttat ttggcatttcaagatgttggtgcttgtgttgccttggtgtctgtgagagtatacttcaaa aagtgcccatttacagtgaagaatctggctatgtttccagacacggtacccatggactcc cagtccctggtggaggttagagggtcttgtgtcaacaattctaaggaggaagatcctcca aggatgtactgcagtacagaaggcgaatggcttgtacccattggcaagtgttcctgcaat gctggctatgaagaaagaggttttatgtgccaagcttgtcgaccaggtttctacaaggca ttggatggtaatatgaagtgtgctaagtgcccgcctcacagttctactcaggaagatggt tcaatgaactgcaggtgtgagaataattacttccgggcagacaaagaccctccatccatg gcttgtacccgacctccatcttcaccaagaaatgttatctctaatataaacgagacctca gttatcctggactggagttggcccctggacacaggaggccggaaagatgttaccttcaac atcatatgtaaaaaatgtgggtggaatataaaacagtgtgagccatgcagcccaaatgtc cgcttcctccctcgacagtttggactcaccaacaccacggtgacagtgacagaccttctg gcacatactaactacacctttgagattgatgccgttaatggggtgtcagagctgagctcc ccaccaagacagtttgctgcggtcagcatcacaactaatcaggctgctccatcacctgtc ctgacgattaagaaagatcggacctccagaaatagcatctctttgtcctggcaagaacct gaacatcctaatgggatcatattggactacgaggtcaaatactatgaaaagcaggaacaa gaaacaagttataccattctgagggcaagaggcacaaatgttaccatcagtagcctcaag cctgacactatatacgtattccaaatccgagcccgaacagccgctggatatgggacgaac agccgcaagtttgagtttgaaactagtccagactctttctccatctctggtgaaagtagc caagtggtcatgatcgccatttcagcggcagtagcaattattctcctcactgttgtcatc tatgttttgattgggaggttctgtggctataagtcaaaacatggggcagatgaaaaaaga cttcattttggcaatgggcatttaaaacttccaggtctcaggacttatgttgacccacat acatatgaagaccctacccaagctgttcatgagtttgccaaggaattggatgccaccaac atatccattgataaagttgttggagcaggtgaatttggagaggtgtgcagtggtcgctta aaacttccttcaaaaaaagagatttcagtggccattaagaccctgaaagttggctacaca gaaaagcagaggagagacttcctgggagaagcaagcattatgggacagtttgaccacccc aatatcattcgactggaaggagttgttaccaaaagtaagccagttatgattgtcacagaa tacatggagaatggttccttggatagtttcctacgtaaacacgatgcccagtttactgtc attcagctagtggggatgcttcgagggatagcatctggcatgaagtacctgtcagacatg ggctatgttcaccgagacctcgctgctcggaacatcttgatcaacagtaacttggtgtgt aaggtttctgatttcggactttcgcgtgtcctggaggatgacccagaagctgcttataca acaagaggagggaagatcccaatcaggtggacatcaccagaagctatagcctaccgcaag ttcacgtcagccagcgatgtatggagttatgggattgttctctgggaggtgatgtcttat ggagagagaccatactgggagatgtccaatcaggatgtaattaaagctgtagatgagggc tatcgactgccaccccccatggactgcccagctgccttgtatcagctgatgctggactgc tggcagaaagacaggaacaacagacccaagtttgagcagattgttagtattctggacaag cttatccggaatcccggcagcctgaagatcatcaccagtgcagccgcaaggccatcaaac cttcttctggaccaaagcaatgtggatatcactaccttccgcacaacaggtgactggctt aatggtgtctggacagcacactgcaaggaaatcttcacgggtgtggagtacagttcttgt gacacaatagccaagatttccacagatgacatgaaaaaggttggtgtcaccgtggttggg ccacagaagaagatcatcagtagcattaaagctctagaaacgcaatcaaagaatggccca gttcccgtgtaa |
Protein Sequence |
>2042 : length: 983 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESS QVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPH TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSN LLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG PQKKIISSIKALETQSKNGPVPV |