Entrez Gene

Basic Information
Gene ID	2042
Name	EPHA3
Synonymous	EPH receptor A3;EPHA3;EPH receptor A3
Definition	EPH-like kinase 4\|TYRO4 protein tyrosine kinase\|eph-like tyrosine kinase 1\|ephrin type-A receptor 3\|human embryo kinase 1\|tyrosine-protein kinase receptor ETK1
Position	3p11.2
Gene Type	protein-coding
Mutation summary:	Mutations in domains Mutational pattern in 17 major cancer types LoF vs missense mutations All the copy number variations from COSMIC database V72 All the mutations from COSMIC database V72

Mutation summary in protein domains

The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

Loss of Function mutations compare to missense mutations

Top

The ratio of the loss-of-function mutations over missense mutations is 0.08.

The copy number variations for various cancers

The copy number variations in 17 major cancer types: 1; Breast, 2; Central nervous system, 3; Cervix, 4; Endometrium, 5; Haematopoietic and lymphoid_tissue, 6; Kidney, 7; Large intestine, 8; Liver, 9; Lung, 10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1826T>C; p.V609A; 3:89413204-89413204	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1305T>C; p.A435A; 3:89342089-89342089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.701C>A; p.S234Y; 3:89210407-89210407	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1099G>T; p.G367W; 3:89341883-89341883	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.807G>A; p.M269I; 3:89210513-89210513	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1178C>A; p.T393K; 3:89341962-89341962	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1066G>A; p.D356N; 3:89341850-89341850	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1843G>A; p.E615K; 3:89413221-89413221	skin	malignant_melanoma	Substitution - Missense
c.2903G>A; p.S968N; 3:89479453-89479453	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.663G>T; p.Q221H; 3:89210369-89210369	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.879C>T; p.H293H; 3:89340980-89340980	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2821G>A; p.D941N; 3:89472594-89472594	skin; extremity	malignant_melanoma	Substitution - Missense
c.1237A>T; p.N413Y; 3:89342021-89342021	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2030T>A; p.F677Y; 3:89419346-89419346	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.722G>A; p.R241K; 3:89210428-89210428	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.620A>C; p.K207T; 3:89210326-89210326	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2298A>G; p.G766G; 3:89431311-89431311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2030T>A; p.F677Y; 3:89419346-89419346	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.620A>C; p.K207T; 3:89210326-89210326	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2741G>A; p.R914H; 3:89472514-89472514	skin	malignant_melanoma	Substitution - Missense
c.2741G>A; p.R914H; 3:89472514-89472514	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2686G>A; p.A896T; 3:89450366-89450366	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1646C>T; p.A549V; 3:89407320-89407320	kidney	other; neoplasm	Substitution - Missense
c.1337A>G; p.D446G; 3:89395867-89395867	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2515G>T; p.E839*; 3:89450195-89450195	breast	carcinoma	Substitution - Nonsense
c.2314G>A; p.E772K; 3:89431327-89431327	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2295C>T; p.F765F; 3:89431308-89431308	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2295C>T; p.F765F; 3:89431308-89431308	skin	malignant_melanoma	Substitution - coding silent
c.2042A>G; p.N681S; 3:89419358-89419358	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.80C>A; p.S27Y; 3:89107828-89107828	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.616G>T; p.V206L; 3:89210322-89210322	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1952C>T; p.A651V; 3:89419268-89419268	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1347C>T; p.S449S; 3:89395877-89395877	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1989G>A; p.Q663Q; 3:89419305-89419305	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1347C>T; p.S449S; 3:89395877-89395877	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1727C>A; p.A576E; 3:89408096-89408096	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2002C>A; p.L668M; 3:89419318-89419318	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.920A>T; p.E307V; 3:89341021-89341021	liver	carcinoma	Substitution - Missense
c.1515C>A; p.Y505*; 3:89399401-89399401	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.866A>T; p.K289M; 3:89340967-89340967	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1773A>C; p.P591P; 3:89413151-89413151	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.2345G>T; p.R782I; 3:89431358-89431358	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1773A>C; p.P591P; 3:89413151-89413151	liver	carcinoma	Substitution - coding silent
c.500A>G; p.E167G; 3:89210206-89210206	ovary	other; neoplasm	Substitution - Missense
c.1773A>C; p.P591P; 3:89413151-89413151	liver	carcinoma	Substitution - coding silent
c.2494G>A; p.D832N; 3:89449372-89449372	breast	carcinoma	Substitution - Missense
c.500A>G; p.E167G; 3:89210206-89210206	ovary	other; neoplasm	Substitution - Missense
c.2788G>A; p.E930K; 3:89472561-89472561	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - Missense
c.2788G>A; p.E930K; 3:89472561-89472561	skin	malignant_melanoma	Substitution - Missense
c.2788G>A; p.E930K; 3:89472561-89472561	skin	malignant_melanoma	Substitution - Missense
c.2497-2A>T; p.?; 3:89450175-89450175	stomach	carcinoma; adenocarcinoma	Unknown
c.1065A>G; p.K355K; 3:89341849-89341849	pancreas	carcinoma	Substitution - coding silent
c.2788G>A; p.E930K; 3:89472561-89472561	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2305C>G; p.R769G; 3:89431318-89431318	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1527C>A; p.I509I; 3:89399413-89399413	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1340G>A; p.R447Q; 3:89395870-89395870	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2421A>G; p.V807V; 3:89449299-89449299	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2275G>T; p.V759L; 3:89431288-89431288	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2734A>T; p.T912S; 3:89472507-89472507	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.178G>A; p.E60K; 3:89209884-89209884	skin	malignant_melanoma	Substitution - Missense
c.470T>A; p.L157H; 3:89210176-89210176	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1958A>G; p.K653R; 3:89419274-89419274	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1665C>A; p.L555L; 3:89407339-89407339	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1834T>A; p.F612I; 3:89413212-89413212	liver	carcinoma	Substitution - Missense
c.1687T>G; p.L563V; 3:89407361-89407361	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.665C>T; p.S222F; 3:89210371-89210371	skin	malignant_melanoma	Substitution - Missense
c.1834T>A; p.F612I; 3:89413212-89413212	liver	carcinoma	Substitution - Missense
c.1951G>A; p.A651T; 3:89419267-89419267	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1635C>A; p.I545I; 3:89407309-89407309	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.927T>A; p.N309K; 3:89341028-89341028	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1957A>G; p.K653E; 3:89419273-89419273	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.271T>C; p.S91P; 3:89209977-89209977	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.600A>C; p.K200N; 3:89210306-89210306	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2730C>T; p.I910I; 3:89472503-89472503	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2690G>T; p.R897M; 3:89450370-89450370	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.2478G>A; p.W826*; 3:89449356-89449356	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2478G>A; p.W826*; 3:89449356-89449356	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2572C>T; p.L858L; 3:89450252-89450252	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2112_2119delTGGTTCCT; p.S706fs*1; 3:89429143-89429150	breast	carcinoma	Deletion - Frameshift
c.1806T>C; p.Y602Y; 3:89413184-89413184	pancreas	carcinoma	Substitution - coding silent
c.213C>T; p.C71C; 3:89209919-89209919	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2156C>T; p.T719I; 3:89431169-89431169	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.364C>A; p.L122M; 3:89210070-89210070	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2323C>G; p.P775A; 3:89431336-89431336	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1874A>C; p.K625T; 3:89413252-89413252	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.364C>A; p.L122M; 3:89210070-89210070	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.364C>A; p.L122M; 3:89210070-89210070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.364C>A; p.L122M; 3:89210070-89210070	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1198C>T; p.L400L; 3:89341982-89341982	skin	malignant_melanoma	Substitution - coding silent
c.385G>T; p.D129Y; 3:89210091-89210091	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1140C>T; p.V380V; 3:89341924-89341924	breast	carcinoma	Substitution - coding silent
c.2771G>T; p.W924L; 3:89472544-89472544	liver	carcinoma	Substitution - Missense
c.1026C>T; p.I342I; 3:89341810-89341810	skin	malignant_melanoma	Substitution - coding silent
c.1188G>T; p.V396V; 3:89341972-89341972	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2771G>T; p.W924L; 3:89472544-89472544	liver	carcinoma	Substitution - Missense
c.2268T>C; p.S756S; 3:89431281-89431281	skin	malignant_melanoma	Substitution - coding silent
c.2282A>G; p.K761R; 3:89431295-89431295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.266G>C; p.R89T; 3:89209972-89209972	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1497C>G; p.L499L; 3:89399383-89399383	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1339C>T; p.R447W; 3:89395869-89395869	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1516G>A; p.V506I; 3:89399402-89399402	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2034C>T; p.D678D; 3:89419350-89419350	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1339C>T; p.R447W; 3:89395869-89395869	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1410C>A; p.Y470*; 3:89395940-89395940	large_intestine	adenoma	Substitution - Nonsense
c.2700C>T; p.N900N; 3:89472473-89472473	skin	malignant_melanoma	Substitution - coding silent
c.2743A>G; p.T915A; 3:89472516-89472516	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.634T>A; p.F212I; 3:89210340-89210340	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1926T>G; p.L642L; 3:89419242-89419242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2533delC; p.M847fs*10; 3:89450213-89450213	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1022T>C; p.V341A; 3:89341806-89341806	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2921C>T; p.T974M; 3:89479471-89479471	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2533delC; p.M847fs*10; 3:89450213-89450213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2590G>T; p.D864Y; 3:89450270-89450270	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.204C>G; p.Y68*; 3:89209910-89209910	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.1552_1553GG>TT; p.G518L; 3:89399438-89399439	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1552_1553GG>TT; p.G518L; 3:89399438-89399439	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2772G>T; p.W924C; 3:89472545-89472545	liver	carcinoma	Substitution - Missense
c.2420T>C; p.V807A; 3:89449298-89449298	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2420T>C; p.V807A; 3:89449298-89449298	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2772G>T; p.W924C; 3:89472545-89472545	liver	carcinoma	Substitution - Missense
c.2248C>T; p.R750W; 3:89431261-89431261	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1677C>A; p.V559V; 3:89407351-89407351	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2774C>A; p.T925K; 3:89472547-89472547	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1581A>T; p.E527D; 3:89399467-89399467	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.514G>T; p.G172C; 3:89210220-89210220	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1458T>G; p.I486M; 3:89399344-89399344	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1432C>A; p.Q478K; 3:89399318-89399318	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1849G>T; p.D617Y; 3:89413227-89413227	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4G>A; p.D2N; 3:89107752-89107752	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.2304G>A; p.S768S; 3:89431317-89431317	liver	carcinoma	Substitution - coding silent
c.2947G>A; p.V983M; 3:89479497-89479497	large_intestine; colon	NS	Substitution - Missense
c.2947G>A; p.V983M; 3:89479497-89479497	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2304G>A; p.S768S; 3:89431317-89431317	liver	carcinoma	Substitution - coding silent
c.2433G>T; p.G811G; 3:89449311-89449311	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.197G>A; p.R66K; 3:89209903-89209903	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.247A>G; p.R83G; 3:89209953-89209953	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1070T>C; p.V357A; 3:89341854-89341854	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.873G>T; p.P291P; 3:89340974-89340974	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2475C>A; p.Y825*; 3:89449353-89449353	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1662T>C; p.I554I; 3:89407336-89407336	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.544G>T; p.A182S; 3:89210250-89210250	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1863A>G; p.I621M; 3:89413241-89413241	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1863A>G; p.I621M; 3:89413241-89413241	liver	carcinoma	Substitution - Missense
c.1629C>T; p.V543V; 3:89407303-89407303	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.407G>A; p.R136Q; 3:89210113-89210113	skin	malignant_melanoma	Substitution - Missense
c.2220G>A; p.M740I; 3:89431233-89431233	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1179G>T; p.T393T; 3:89341963-89341963	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1179G>T; p.T393T; 3:89341963-89341963	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.282G>A; p.K94K; 3:89209988-89209988	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.407G>A; p.R136Q; 3:89210113-89210113	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1356C>T; p.S452S; 3:89395886-89395886	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1179G>T; p.T393T; 3:89341963-89341963	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1101G>T; p.G367G; 3:89341885-89341885	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2088G>T; p.M696I; 3:89429119-89429119	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1668C>G; p.L556L; 3:89407342-89407342	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2741G>T; p.R914L; 3:89472514-89472514	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1308_1309TC>AA; p.A436>?; 3:89395838-89395839	lung	carcinoma; adenocarcinoma	Complex
c.2054T>C; p.L685P; 3:89419370-89419370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2649G>C; p.R883R; 3:89450329-89450329	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.253A>G; p.N85D; 3:89209959-89209959	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.709G>A; p.E237K; 3:89210415-89210415	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.142C>G; p.P48A; 3:89127262-89127262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1365G>C; p.L455F; 3:89395895-89395895	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1907G>T; p.C636F; 3:89419223-89419223	stomach	carcinoma	Substitution - Missense
c.175G>T; p.D59Y; 3:89209881-89209881	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.947A>C; p.D316A; 3:89341048-89341048	breast	carcinoma	Substitution - Missense
c.1568A>C; p.K523T; 3:89399454-89399454	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.119G>A; p.G40E; 3:89127239-89127239	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1123C>T; p.P375S; 3:89341907-89341907	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1963C>T; p.L655L; 3:89419279-89419279	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1543delG; p.A515fs*30; 3:89399429-89399429	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.1765A>C; p.K589Q; 3:89413143-89413143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1543delG; p.A515fs*30; 3:89399429-89399429	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.267G>A; p.R89R; 3:89209973-89209973	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.267G>T; p.R89S; 3:89209973-89209973	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2283G>T; p.K761N; 3:89431296-89431296	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.224A>G; p.D75G; 3:89209930-89209930	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2445G>A; p.W815*; 3:89449323-89449323	skin	malignant_melanoma	Substitution - Nonsense
c.153G>T; p.G51G; 3:89127273-89127273	breast	carcinoma	Substitution - coding silent
c.2208C>T; p.Y736Y; 3:89431221-89431221	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.750G>T; p.W250C; 3:89210456-89210456	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.476A>G; p.D159G; 3:89210182-89210182	large_intestine; colon	NS	Substitution - Missense
c.2530C>T; p.P844S; 3:89450210-89450210	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2297G>T; p.G766V; 3:89431310-89431310	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1457T>C; p.I486T; 3:89399343-89399343	breast	carcinoma	Substitution - Missense
c.1379C>A; p.P460H; 3:89395909-89395909	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1347C>A; p.S449S; 3:89395877-89395877	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.440C>T; p.A147V; 3:89210146-89210146	skin	malignant_melanoma	Substitution - Missense
c.2416G>A; p.D806N; 3:89449294-89449294	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2540T>A; p.M847K; 3:89450220-89450220	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.806T>C; p.M269T; 3:89210512-89210512	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.438T>G; p.I146M; 3:89210144-89210144	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.485T>A; p.L162Q; 3:89210191-89210191	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.716C>T; p.P239L; 3:89210422-89210422	skin	malignant_melanoma	Substitution - Missense
c.1641T>A; p.I547I; 3:89407315-89407315	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.758C>A; p.P253H; 3:89210464-89210464	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1898G>A; p.G633E; 3:89419214-89419214	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1641T>A; p.I547I; 3:89407315-89407315	pancreas	carcinoma	Substitution - coding silent
c.935G>A; p.R312Q; 3:89341036-89341036	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1875A>G; p.K625K; 3:89413253-89413253	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.935G>A; p.R312Q; 3:89341036-89341036	liver	carcinoma	Substitution - Missense
c.935G>A; p.R312Q; 3:89341036-89341036	liver	carcinoma	Substitution - Missense
c.2748A>G; p.T916T; 3:89472521-89472521	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1179G>A; p.T393T; 3:89341963-89341963	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1462A>T; p.R488W; 3:89399348-89399348	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.970+1G>T; p.?; 3:89341072-89341072	lung	carcinoma; adenocarcinoma	Unknown
c.1435G>A; p.E479K; 3:89399321-89399321	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.745G>A; p.E249K; 3:89210451-89210451	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1636G>A; p.A546T; 3:89407310-89407310	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1636G>A; p.A546T; 3:89407310-89407310	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1672G>A; p.V558I; 3:89407346-89407346	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.110C>A; p.T37K; 3:89127230-89127230	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1944T>C; p.I648I; 3:89419260-89419260	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1375G>T; p.E459*; 3:89395905-89395905	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.119G>T; p.G40V; 3:89127239-89127239	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1535G>A; p.R512Q; 3:89399421-89399421	breast	carcinoma	Substitution - Missense
c.1233C>A; p.A411A; 3:89342017-89342017	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.1357A>G; p.I453V; 3:89395887-89395887	kidney	other; neoplasm	Substitution - Missense
c.1811A>T; p.D604V; 3:89413189-89413189	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2835G>C; p.K945N; 3:89472608-89472608	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1525A>T; p.I509F; 3:89399411-89399411	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.282G>T; p.K94N; 3:89209988-89209988	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2408C>T; p.S803L; 3:89449286-89449286	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1228G>C; p.D410H; 3:89342012-89342012	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.282G>T; p.K94N; 3:89209988-89209988	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1142G>A; p.R381H; 3:89341926-89341926	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058G>T; p.G353V; 3:89341842-89341842	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1020A>C; p.S340S; 3:89341804-89341804	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.392A>G; p.H131R; 3:89210098-89210098	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.911G>C; p.C304S; 3:89341012-89341012	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2423G>T; p.W808L; 3:89449301-89449301	oesophagus	carcinoma	Substitution - Missense
c.1090delA; p.K365fs*6; 3:89341874-89341874	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.236A>T; p.N79I; 3:89209942-89209942	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1915C>T; p.R639C; 3:89419231-89419231	skin	malignant_melanoma	Substitution - Missense
c.2691G>A; p.R897R; 3:89472464-89472464	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.970+7A>T; p.?; 3:89341078-89341078	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1891G>A; p.E631K; 3:89419207-89419207	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1440A>T; p.Q480H; 3:89399326-89399326	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.98T>G; p.L33R; 3:89127218-89127218	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2496T>C; p.D832D; 3:89449374-89449374	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.341G>A; p.G114E; 3:89210047-89210047	NS	malignant_melanoma	Substitution - Missense
c.621G>A; p.K207K; 3:89210327-89210327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.623A>C; p.N208T; 3:89210329-89210329	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.621G>A; p.K207K; 3:89210327-89210327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.341G>A; p.G114E; 3:89210047-89210047	skin	malignant_melanoma	Substitution - Missense
c.2418T>C; p.D806D; 3:89449296-89449296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1595-3C>T; p.?; 3:89407266-89407266	liver	carcinoma	Unknown
c.2418T>C; p.D806D; 3:89449296-89449296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1734A>C; p.E578D; 3:89408103-89408103	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.687T>C; p.S229S; 3:89210393-89210393	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.687T>C; p.S229S; 3:89210393-89210393	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1595-3C>T; p.?; 3:89407266-89407266	liver	carcinoma	Unknown
c.687T>C; p.S229S; 3:89210393-89210393	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2143G>T; p.D715Y; 3:89431156-89431156	kidney	other; neoplasm	Substitution - Missense
c.687T>C; p.S229S; 3:89210393-89210393	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1810G>T; p.D604Y; 3:89413188-89413188	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2423G>A; p.W808*; 3:89449301-89449301	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Nonsense
c.1601C>T; p.S534F; 3:89407275-89407275	skin	malignant_melanoma	Substitution - Missense
c.109A>G; p.T37A; 3:89127229-89127229	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.109A>G; p.T37A; 3:89127229-89127229	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1941G>T; p.E647D; 3:89419257-89419257	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2607C>G; p.P869P; 3:89450287-89450287	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2494G>T; p.D832Y; 3:89449372-89449372	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.109A>G; p.T37A; 3:89127229-89127229	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2870C>T; p.T957I; 3:89479420-89479420	skin	malignant_melanoma	Substitution - Missense
c.1583C>A; p.T528N; 3:89399469-89399469	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2579G>A; p.C860Y; 3:89450259-89450259	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2282A>T; p.K761M; 3:89431295-89431295	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1925T>G; p.L642R; 3:89419241-89419241	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2845G>A; p.D949N; 3:89472618-89472618	skin	malignant_melanoma	Substitution - Missense
c.1925T>G; p.L642R; 3:89419241-89419241	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2845G>A; p.D949N; 3:89472618-89472618	skin	malignant_melanoma	Substitution - Missense
c.1792G>A; p.D598N; 3:89413170-89413170	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1925T>G; p.L642R; 3:89419241-89419241	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2173G>C; p.G725R; 3:89431186-89431186	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.573C>G; p.A191A; 3:89210279-89210279	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2288C>T; p.S763F; 3:89431301-89431301	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.2774C>T; p.T925I; 3:89472547-89472547	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.561T>G; p.G187G; 3:89210267-89210267	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2310C>T; p.V770V; 3:89431323-89431323	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2187G>A; p.G729G; 3:89431200-89431200	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1986G>A; p.K662K; 3:89419302-89419302	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.934C>T; p.R312W; 3:89341035-89341035	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1682A>T; p.Y561F; 3:89407356-89407356	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.318C>A; p.C106*; 3:89210024-89210024	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2285T>G; p.V762G; 3:89431298-89431298	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.662A>T; p.Q221L; 3:89210368-89210368	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2262C>A; p.I754I; 3:89431275-89431275	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1969G>T; p.V657F; 3:89419285-89419285	bone; rib	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2222G>A; p.G741D; 3:89431235-89431235	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.631A>G; p.M211V; 3:89210337-89210337	liver	carcinoma	Substitution - Missense
c.2060G>A; p.G687E; 3:89419376-89419376	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.329C>T; p.P110L; 3:89210035-89210035	skin	malignant_melanoma	Substitution - Missense
c.28C>T; p.L10F; 3:89107776-89107776	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1246T>C; p.S416P; 3:89342030-89342030	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2181T>C; p.L727L; 3:89431194-89431194	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.148C>T; p.H50Y; 3:89127268-89127268	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.799G>T; p.G267C; 3:89210505-89210505	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2584C>T; p.Q862*; 3:89450264-89450264	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.237C>A; p.N79K; 3:89209943-89209943	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1405G>A; p.D469N; 3:89395935-89395935	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1405G>A; p.D469N; 3:89395935-89395935	breast	carcinoma	Substitution - Missense
c.484C>T; p.L162L; 3:89210190-89210190	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1968A>C; p.K656N; 3:89419284-89419284	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.970+1G>A; p.?; 3:89341072-89341072	lung	carcinoma; adenocarcinoma	Unknown
c.1819C>A; p.Q607K; 3:89413197-89413197	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.970+1G>A; p.?; 3:89341072-89341072	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.1759C>T; p.H587Y; 3:89408128-89408128	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1240G>A; p.G414R; 3:89342024-89342024	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2641C>A; p.L881I; 3:89450321-89450321	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1320C>A; p.V440V; 3:89395850-89395850	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.696C>A; p.N232K; 3:89210402-89210402	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.559G>A; p.G187S; 3:89210265-89210265	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1336G>T; p.D446Y; 3:89395866-89395866	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2800G>A; p.G934S; 3:89472573-89472573	skin	malignant_melanoma	Substitution - Missense
c.559G>A; p.G187S; 3:89210265-89210265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1861A>C; p.I621L; 3:89413239-89413239	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2537C>T; p.P846L; 3:89450217-89450217	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.254A>G; p.N85S; 3:89209960-89209960	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.254A>G; p.N85S; 3:89209960-89209960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.254A>G; p.N85S; 3:89209960-89209960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.254A>G; p.N85S; 3:89209960-89209960	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2537C>T; p.P846L; 3:89450217-89450217	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.855G>A; p.M285I; 3:89340956-89340956	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.855G>A; p.M285I; 3:89340956-89340956	skin	malignant_melanoma	Substitution - Missense
c.2472A>T; p.P824P; 3:89449350-89449350	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1072A>G; p.T358A; 3:89341856-89341856	prostate	carcinoma	Substitution - Missense
c.1522C>A; p.Q508K; 3:89399408-89399408	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995T>C; p.V332A; 3:89341779-89341779	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.676G>A; p.V226I; 3:89210382-89210382	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2734A>G; p.T912A; 3:89472507-89472507	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1402T>G; p.L468V; 3:89395932-89395932	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2946C>T; p.P982P; 3:89479496-89479496	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.686C>A; p.S229Y; 3:89210392-89210392	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.686C>A; p.S229Y; 3:89210392-89210392	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.248G>A; p.R83K; 3:89209954-89209954	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.318C>T; p.C106C; 3:89210024-89210024	prostate	carcinoma	Substitution - coding silent
c.453T>C; p.S151S; 3:89210159-89210159	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.834C>A; p.Y278*; 3:89340935-89340935	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.248G>A; p.R83K; 3:89209954-89209954	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2611T>G; p.F871V; 3:89450291-89450291	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2184A>G; p.R728R; 3:89431197-89431197	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2922G>A; p.T974T; 3:89479472-89479472	prostate	carcinoma	Substitution - coding silent
c.1180G>A; p.V394M; 3:89341964-89341964	skin	malignant_melanoma	Substitution - Missense
c.2184A>G; p.R728R; 3:89431197-89431197	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1271A>G; p.Q424R; 3:89342055-89342055	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.790G>A; p.E264K; 3:89210496-89210496	skin	malignant_melanoma	Substitution - Missense
c.2372C>T; p.T791I; 3:89449250-89449250	prostate	adenoma	Substitution - Missense
c.2175G>A; p.G725G; 3:89431188-89431188	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.620A>T; p.K207M; 3:89210326-89210326	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1097G>T; p.C366F; 3:89341881-89341881	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2648G>A; p.R883Q; 3:89450328-89450328	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1760A>T; p.H587L; 3:89408129-89408129	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1381G>T; p.E461*; 3:89395911-89395911	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Nonsense
c.2518G>A; p.G840S; 3:89450198-89450198	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2056G>A; p.E686K; 3:89419372-89419372	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1564C>A; p.R522S; 3:89399450-89399450	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1381G>T; p.E461*; 3:89395911-89395911	kidney	other; neoplasm	Substitution - Nonsense
c.957C>T; p.S319S; 3:89341058-89341058	skin	malignant_melanoma	Substitution - coding silent
c.957C>T; p.S319S; 3:89341058-89341058	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.466G>A; p.D156N; 3:89210172-89210172	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.771T>A; p.C257*; 3:89210477-89210477	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1132C>A; p.P378T; 3:89341916-89341916	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2882C>G; p.P961R; 3:89479432-89479432	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.748T>A; p.W250R; 3:89210454-89210454	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.236A>C; p.N79T; 3:89209942-89209942	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.304A>T; p.T102S; 3:89210010-89210010	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.54C>A; p.S18R; 3:89107802-89107802	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1692T>C; p.I564I; 3:89407366-89407366	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1236T>C; p.V412V; 3:89342020-89342020	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2305C>A; p.R769S; 3:89431318-89431318	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.602A>C; p.K201T; 3:89210308-89210308	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1502C>T; p.P501L; 3:89399388-89399388	skin	malignant_melanoma	Substitution - Missense
c.2266A>G; p.S756G; 3:89431279-89431279	central_nervous_system; brain	glioma	Substitution - Missense
c.1932_1933insA; p.E647fs*7; 3:89419248-89419249	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.65T>A; p.L22Q; 3:89107813-89107813	ovary	other; neoplasm	Substitution - Missense
c.1918T>A; p.L640I; 3:89419234-89419234	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1361C>T; p.S454F; 3:89395891-89395891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.311G>A; p.R104Q; 3:89210017-89210017	skin	malignant_melanoma	Substitution - Missense
c.2415C>G; p.S805R; 3:89449293-89449293	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.311G>A; p.R104Q; 3:89210017-89210017	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1339C>A; p.R447R; 3:89395869-89395869	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.188C>A; p.T63K; 3:89209894-89209894	oesophagus	carcinoma	Substitution - Missense
c.1336G>A; p.D446N; 3:89395866-89395866	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2712C>G; p.D904E; 3:89472485-89472485	breast	carcinoma	Substitution - Missense
c.2241C>T; p.L747L; 3:89431254-89431254	skin	malignant_melanoma	Substitution - coding silent
c.2241C>T; p.L747L; 3:89431254-89431254	skin	malignant_melanoma	Substitution - coding silent
c.1750G>A; p.G584S; 3:89408119-89408119	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.388G>A; p.D130N; 3:89210094-89210094	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2147C>T; p.A716V; 3:89431160-89431160	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2147C>T; p.A716V; 3:89431160-89431160	breast	carcinoma	Substitution - Missense
c.2034C>A; p.D678E; 3:89419350-89419350	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.892G>A; p.E298K; 3:89340993-89340993	skin	malignant_melanoma	Substitution - Missense
c.892G>A; p.E298K; 3:89340993-89340993	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.676G>T; p.V226F; 3:89210382-89210382	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1813C>T; p.P605S; 3:89413191-89413191	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2950T>C; p.*984Q; 3:89479500-89479500	endometrium	carcinoma; endometrioid_carcinoma	Nonstop extension
c.685T>C; p.S229P; 3:89210391-89210391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.685T>C; p.S229P; 3:89210391-89210391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2121G>A; p.L707L; 3:89429152-89429152	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.68T>C; p.I23T; 3:89107816-89107816	liver	carcinoma	Substitution - Missense
c.685T>C; p.S229P; 3:89210391-89210391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2528T>G; p.L843R; 3:89450208-89450208	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2747C>T; p.T916I; 3:89472520-89472520	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.644C>T; p.T215M; 3:89210350-89210350	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.644C>T; p.T215M; 3:89210350-89210350	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.496A>G; p.T166A; 3:89210202-89210202	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.496A>G; p.T166A; 3:89210202-89210202	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.496A>G; p.T166A; 3:89210202-89210202	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.989G>T; p.R330I; 3:89341773-89341773	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2662C>A; p.L888M; 3:89450342-89450342	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1732G>A; p.E578K; 3:89408101-89408101	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2016C>A; p.S672R; 3:89419332-89419332	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.14T>C; p.L5P; 3:89107762-89107762	pancreas	carcinoma	Substitution - Missense
c.14T>C; p.L5P; 3:89107762-89107762	pancreas	carcinoma	Substitution - Missense
c.1691T>A; p.I564N; 3:89407365-89407365	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.497C>A; p.T166N; 3:89210203-89210203	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.722G>T; p.R241M; 3:89210428-89210428	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.645G>A; p.T215T; 3:89210351-89210351	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2426G>T; p.S809I; 3:89449304-89449304	central_nervous_system; brain	glioma	Substitution - Missense
c.1234G>A; p.V412I; 3:89342018-89342018	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.645G>A; p.T215T; 3:89210351-89210351	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1234G>A; p.V412I; 3:89342018-89342018	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1672G>C; p.V558L; 3:89407346-89407346	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1318G>T; p.V440F; 3:89395848-89395848	oesophagus	carcinoma	Substitution - Missense
c.2770T>C; p.W924R; 3:89472543-89472543	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2918A>G; p.E973G; 3:89479468-89479468	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1616G>A; p.S539N; 3:89407290-89407290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1916G>A; p.R639H; 3:89419232-89419232	liver	carcinoma	Substitution - Missense
c.380C>A; p.S127Y; 3:89210086-89210086	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2174G>A; p.G725E; 3:89431187-89431187	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.750G>A; p.W250*; 3:89210456-89210456	skin	malignant_melanoma	Substitution - Nonsense
c.89-3T>C; p.?; 3:89127206-89127206	pancreas	NS	Unknown
c.793G>A; p.E265K; 3:89210499-89210499	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2306G>A; p.R769H; 3:89431319-89431319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.2306G>A; p.R769H; 3:89431319-89431319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.494A>G; p.N165S; 3:89210200-89210200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2306G>A; p.R769H; 3:89431319-89431319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2306G>A; p.R769H; 3:89431319-89431319	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1303G>T; p.A435S; 3:89342087-89342087	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>T; p.A435S; 3:89342087-89342087	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2781C>T; p.H927H; 3:89472554-89472554	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1326G>A; p.T442T; 3:89395856-89395856	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2739C>T; p.F913F; 3:89472512-89472512	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2236G>A; p.D746N; 3:89431249-89431249	skin	malignant_melanoma	Substitution - Missense
c.1961C>T; p.T654I; 3:89419277-89419277	skin	malignant_melanoma	Substitution - Missense
c.2236G>A; p.D746N; 3:89431249-89431249	skin	malignant_melanoma	Substitution - Missense
c.2701C>T; p.L901F; 3:89472474-89472474	skin	malignant_melanoma	Substitution - Missense
c.2148C>T; p.A716A; 3:89431161-89431161	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.333G>C; p.L111F; 3:89210039-89210039	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.155G>A; p.W52*; 3:89209861-89209861	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.754G>T; p.V252L; 3:89210460-89210460	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.397G>T; p.V133L; 3:89210103-89210103	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1543G>A; p.A515T; 3:89399429-89399429	urinary_tract; bladder	carcinoma	Substitution - Missense
c.17C>A; p.S6Y; 3:89107765-89107765	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1543G>A; p.A515T; 3:89399429-89399429	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.2575G>A; p.D859N; 3:89450255-89450255	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.873G>A; p.P291P; 3:89340974-89340974	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2872G>A; p.V958M; 3:89479422-89479422	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2406G>A; p.T802T; 3:89449284-89449284	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2406G>A; p.T802T; 3:89449284-89449284	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1543G>A; p.A515T; 3:89399429-89399429	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2406G>A; p.T802T; 3:89449284-89449284	pancreas	carcinoma	Substitution - coding silent
c.1854C>A; p.A618A; 3:89413232-89413232	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2242G>A; p.A748T; 3:89431255-89431255	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1363T>G; p.L455V; 3:89395893-89395893	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1730A>T; p.D577V; 3:89408099-89408099	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2702T>G; p.L901R; 3:89472475-89472475	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1812C>A; p.D604E; 3:89413190-89413190	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2698A>C; p.N900H; 3:89472471-89472471	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.517C>T; p.P173S; 3:89210223-89210223	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1896T>C; p.F632F; 3:89419212-89419212	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.953C>A; p.P318Q; 3:89341054-89341054	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1705G>T; p.G569C; 3:89408074-89408074	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1936A>G; p.K646E; 3:89419252-89419252	skin	malignant_melanoma	Substitution - Missense
c.1332G>T; p.K444N; 3:89395862-89395862	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1346C>T; p.S449F; 3:89395876-89395876	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1346C>T; p.S449F; 3:89395876-89395876	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1698G>C; p.R566S; 3:89408067-89408067	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1094A>G; p.K365R; 3:89341878-89341878	skin	malignant_melanoma	Substitution - Missense
c.1346C>T; p.S449F; 3:89395876-89395876	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2142C>T; p.H714H; 3:89431155-89431155	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2725G>A; p.D909N; 3:89472498-89472498	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.682G>A; p.G228R; 3:89210388-89210388	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2073A>T; p.K691N; 3:89419389-89419389	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.485T>G; p.L162R; 3:89210191-89210191	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2088G>A; p.M696I; 3:89429119-89429119	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1668C>T; p.L556L; 3:89407342-89407342	liver	carcinoma	Substitution - coding silent
c.1579G>T; p.E527*; 3:89399465-89399465	central_nervous_system; brain	glioma	Substitution - Nonsense
c.1668C>T; p.L556L; 3:89407342-89407342	liver	carcinoma	Substitution - coding silent
c.2051G>A; p.R684Q; 3:89419367-89419367	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2757G>A; p.W919*; 3:89472530-89472530	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1870G>T; p.D624Y; 3:89413248-89413248	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.462A>T; p.Q154H; 3:89210168-89210168	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.545C>T; p.A182V; 3:89210251-89210251	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1785T>G; p.T595T; 3:89413163-89413163	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2317G>A; p.D773N; 3:89431330-89431330	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1011C>G; p.N337K; 3:89341795-89341795	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.897T>C; p.D299D; 3:89340998-89340998	liver	carcinoma	Substitution - coding silent
c.897T>C; p.D299D; 3:89340998-89340998	liver	carcinoma	Substitution - coding silent
c.2104A>C; p.M702L; 3:89429135-89429135	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1345T>C; p.S449P; 3:89395875-89395875	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2183G>T; p.R728L; 3:89431196-89431196	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.142C>T; p.P48S; 3:89127262-89127262	skin	malignant_melanoma	Substitution - Missense
c.2183G>T; p.R728L; 3:89431196-89431196	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1485C>A; p.T495T; 3:89399371-89399371	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.559G>C; p.G187R; 3:89210265-89210265	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2063T>A; p.V688D; 3:89419379-89419379	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.884C>A; p.S295Y; 3:89340985-89340985	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.847G>A; p.G283S; 3:89340948-89340948	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1846T>C; p.L616L; 3:89413224-89413224	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.406C>T; p.R136*; 3:89210112-89210112	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.406C>T; p.R136*; 3:89210112-89210112	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.138T>C; p.S46S; 3:89127258-89127258	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1694_1695GG>AA; p.G565E; 3:89407368-89407369	skin	malignant_melanoma	Substitution - Missense
c.406C>T; p.R136*; 3:89210112-89210112	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.406C>T; p.R136*; 3:89210112-89210112	skin	malignant_melanoma	Substitution - Nonsense
c.406C>T; p.R136*; 3:89210112-89210112	skin	malignant_melanoma	Substitution - Nonsense
c.1146C>T; p.F382F; 3:89341930-89341930	skin	malignant_melanoma	Substitution - coding silent
c.1256G>C; p.S419T; 3:89342040-89342040	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2847-2A>T; p.?; 3:89479395-89479395	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.127G>T; p.G43C; 3:89127247-89127247	oesophagus	carcinoma	Substitution - Missense
c.1082T>C; p.I361T; 3:89341866-89341866	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1281G>A; p.A427A; 3:89342065-89342065	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1073C>T; p.T358I; 3:89341857-89341857	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2168T>C; p.L723P; 3:89431181-89431181	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1169C>A; p.T390N; 3:89341953-89341953	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1674T>C; p.V558V; 3:89407348-89407348	liver	carcinoma	Substitution - coding silent
c.2297G>A; p.G766E; 3:89431310-89431310	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.2297G>A; p.G766E; 3:89431310-89431310	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.2284G>A; p.V762I; 3:89431297-89431297	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1883G>A; p.G628E; 3:89413261-89413261	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.815-8G>T; p.?; 3:89340908-89340908	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1354A>T; p.S452C; 3:89395884-89395884	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.157G>A; p.E53K; 3:89209863-89209863	skin	malignant_melanoma	Substitution - Missense
c.2717G>T; p.S906I; 3:89472490-89472490	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1153C>T; p.R385*; 3:89341937-89341937	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.485T>C; p.L162P; 3:89210191-89210191	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.485T>C; p.L162P; 3:89210191-89210191	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1422C>A; p.Y474*; 3:89395952-89395952	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.285T>G; p.I95M; 3:89209991-89209991	skin	malignant_melanoma	Substitution - Missense
c.1532C>T; p.A511V; 3:89399418-89399418	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>C; p.K176N; 3:89210234-89210234	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2249G>T; p.R750L; 3:89431262-89431262	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1647G>A; p.A549A; 3:89407321-89407321	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2710G>A; p.D904N; 3:89472483-89472483	skin	malignant_melanoma	Substitution - Missense
c.353A>G; p.E118G; 3:89210059-89210059	skin; neck	malignant_melanoma	Substitution - Missense
c.1647G>A; p.A549A; 3:89407321-89407321	skin	malignant_melanoma	Substitution - coding silent
c.15C>T; p.L5L; 3:89107763-89107763	skin	malignant_melanoma	Substitution - coding silent
c.1643C>A; p.S548*; 3:89407317-89407317	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.753T>G; p.L251L; 3:89210459-89210459	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1029G>A; p.L343L; 3:89341813-89341813	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1150C>T; p.P384S; 3:89341934-89341934	skin	malignant_melanoma	Substitution - Missense
c.1643C>A; p.S548*; 3:89407317-89407317	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Nonsense
c.2184A>T; p.R728R; 3:89431197-89431197	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2249G>A; p.R750Q; 3:89431262-89431262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.165C>T; p.I55I; 3:89209871-89209871	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.362A>G; p.N121S; 3:89210068-89210068	skin	malignant_melanoma	Substitution - Missense
c.58_59GG>AA; p.G20K; 3:89107806-89107807	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2249G>A; p.R750Q; 3:89431262-89431262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2051G>C; p.R684P; 3:89419367-89419367	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1837G>T; p.A613S; 3:89413215-89413215	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.947A>T; p.D316V; 3:89341048-89341048	breast	carcinoma	Substitution - Missense
c.931T>C; p.F311L; 3:89341032-89341032	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.219C>G; p.V73V; 3:89209925-89209925	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.563C>T; p.A188V; 3:89210269-89210269	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1889-2A>T; p.?; 3:89419203-89419203	lung	carcinoma; adenocarcinoma	Unknown
c.1177A>G; p.T393A; 3:89341961-89341961	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.684G>T; p.G228G; 3:89210390-89210390	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1177A>G; p.T393A; 3:89341961-89341961	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1556C>T; p.T519M; 3:89399442-89399442	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1280C>T; p.A427V; 3:89342064-89342064	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1284C>T; p.V428V; 3:89342068-89342068	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.744C>T; p.G248G; 3:89210450-89210450	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.744C>T; p.G248G; 3:89210450-89210450	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1970T>A; p.V657D; 3:89419286-89419286	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.839C>T; p.A280V; 3:89340940-89340940	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2667G>A; p.K889K; 3:89450347-89450347	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.399G>A; p.V133V; 3:89210105-89210105	skin	malignant_melanoma	Substitution - coding silent
c.1137T>G; p.N379K; 3:89341921-89341921	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.559G>T; p.G187C; 3:89210265-89210265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1432-2A>G; p.?; 3:89399316-89399316	ovary	carcinoma; serous_carcinoma	Unknown
c.1432-2A>G; p.?; 3:89399316-89399316	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.1432-2A>G; p.?; 3:89399316-89399316	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.2098G>A; p.E700K; 3:89429129-89429129	skin	malignant_melanoma	Substitution - Missense
c.594C>G; p.Y198*; 3:89210300-89210300	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2811C>G; p.Y937*; 3:89472584-89472584	lung	carcinoma; adenocarcinoma	Substitution - Nonsense

Mutation summary in protein domains

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The non-synonymous (top) and synonymous (bottom) mutational percentage for various cancers

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Loss of Function mutations compare to missense mutations

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The copy number variations for various cancers

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COSMIC somatic mutation [Top]